SitesBLAST

Q0QLF3 Nicotinate dehydrogenase small FeS subunit; NDH; Nicotinic acid hydroxylase small FeS subunit; NAH; EC 1.17.1.5 from Eubacterium barkeri (Clostridium barkeri) (see paper)
41% identity, 96% coverage: 4:149/152 of query aligns to 8:154/157 of Q0QLF3

query
sites
Q0QLF3

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C42 (= C38) binding [2Fe-2S] cluster
C47 (= C43) binding [2Fe-2S] cluster
C50 (= C46) binding [2Fe-2S] cluster
C62 (= C58) binding [2Fe-2S] cluster
C101 (= C96) binding [2Fe-2S] cluster
C104 (= C99) binding [2Fe-2S] cluster
C136 (= C131) binding [2Fe-2S] cluster
C138 (= C133) binding [2Fe-2S] cluster

3hrdD Crystal structure of nicotinate dehydrogenase (see paper)
41% identity, 96% coverage: 4:149/152 of query aligns to 8:154/160 of 3hrdD

query
sites
3hrdD

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binding flavin-adenine dinucleotide: E44 (≠ V40), G45 (≠ A41), E46 (≠ Q42)
binding fe2/s2 (inorganic) cluster: E40 (≠ F36), C42 (= C38), S43 (≠ G39), G45 (≠ A41), C47 (= C43), G48 (= G44), C50 (= C46), C62 (= C58), Q100 (= Q95), C101 (= C96), G102 (= G97), C104 (= C99), C136 (= C131), C138 (= C133)
binding pterin cytosine dinucleotide: Q100 (= Q95), C138 (= C133)

8uemC The cryoem structure of the high affinity carbon monoxide dehydrogenase from mycobacterium smegmatis (see paper)
40% identity, 96% coverage: 4:149/152 of query aligns to 5:151/153 of 8uemC

query
sites
8uemC

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binding fe2/s2 (inorganic) cluster: W37 (≠ F36), G38 (= G37), C39 (= C38), S42 (≠ A41), N43 (≠ Q42), C44 (= C43), G45 (= G44), C47 (= C46), K57 (≠ R56), C59 (= C58), C98 (= C96), G99 (= G97), C101 (= C99), C133 (= C131), C135 (= C133)
binding pterin cytosine dinucleotide: Q97 (= Q95), C135 (= C133)

1ffuD Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava which lacks the mo-pyranopterin moiety of the molybdenum cofactor (see paper)
38% identity, 97% coverage: 4:151/152 of query aligns to 7:155/156 of 1ffuD

query
sites
1ffuD

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binding fe2/s2 (inorganic) cluster: C41 (= C38), S44 (≠ A41), H45 (≠ Q42), C46 (= C43), G47 (= G44), C49 (= C46), C61 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C135 (= C131), C137 (= C133)

1ffvA Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava (see paper)
38% identity, 97% coverage: 4:151/152 of query aligns to 6:154/155 of 1ffvA

query
sites
1ffvA

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binding fe2/s2 (inorganic) cluster: I38 (≠ F36), C40 (= C38), S43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), C60 (= C58), C99 (= C96), G100 (= G97), C102 (= C99), C134 (= C131), C136 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q98 (= Q95), C136 (= C133)

1n5wA Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form (see paper)
41% identity, 98% coverage: 4:152/152 of query aligns to 6:156/161 of 1n5wA

query
sites
1n5wA

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binding flavin-adenine dinucleotide: S43 (≠ A41), H44 (≠ Q42)
binding fe2/s2 (inorganic) cluster: I38 (≠ F36), G39 (= G37), C40 (= C38), S43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C135 (= C131), C137 (= C133)

P19921 Carbon monoxide dehydrogenase small chain; CO dehydrogenase subunit S; CO-DH S; EC 1.2.5.3 from Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans) (see 2 papers)
41% identity, 98% coverage: 4:152/152 of query aligns to 8:158/166 of P19921

query
sites
P19921

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G

C42 (= C38) binding [2Fe-2S] cluster
C47 (= C43) binding [2Fe-2S] cluster
C50 (= C46) binding [2Fe-2S] cluster
C62 (= C58) binding [2Fe-2S] cluster
C102 (= C96) binding [2Fe-2S] cluster
C105 (= C99) binding [2Fe-2S] cluster
C137 (= C131) binding [2Fe-2S] cluster
C139 (= C133) binding [2Fe-2S] cluster

1n5wD Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form (see paper)
41% identity, 98% coverage: 4:152/152 of query aligns to 6:156/158 of 1n5wD

query
sites
1n5wD

V

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T

T

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N

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A

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Q

V

Q

G

N

L

L

T

T

G

G

T

A

K

H

F

I

G

G

C
|
C

G

D

V

T

A
x
S

Q
x
H

C
|
C

G
|
G

A

A

C
|
C

T

T

V

V

Y

D

V

L

D

D

G

G

S

M

P

S

V

V

R

K

S

S

C
|
C

Q

T

T

M

F

F

I

A

G

V

D

Q

I

A

E

N

G

G

A

A

K

S

V

I

T

T

I

I

E

E

G

G

L

M

Q

A

G

A

K

P

-

D

-

G

V

T

A

L

E

S

A

A

V

L

Q

Q

A

E

I

G

W

F

A

R

D

M

L

M

D

H

V

G

P

L

Q
|
Q

C
|
C

G
|
G

Y

Y

C
|
C

Q

T

S

P

G

G

Q

M

I

I

M

M

S

R

A

S

T

H

D

R

L

L

V

Q

N

E

N

N

P

P

K

S

P

P

S

T

D

E

E

A

D

E

I

I

D

R

A

F

A

G

M

I

S

G

G

G

N

N

L

L

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

Q

R

N

I

I

R

V

A

K

G

A

I

I

H

Q

E

Y

A

A

K

A

R

K

L

I

E

N

G

G

binding flavin-adenine dinucleotide: S43 (≠ A41), H44 (≠ Q42)
binding fe2/s2 (inorganic) cluster: C40 (= C38), S43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C135 (= C131), C137 (= C133)
binding pterin cytosine dinucleotide: Q99 (= Q95), C137 (= C133)

4usaA Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with trans-cinnamaldehyde (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 4usaA

query
sites
4usaA

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding bicarbonate ion: 460, 531, 532, 535, 539
binding hydrocinnamic acid: 255, 425, 494, 497, 535, 626
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 697, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

4us9A Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with 3- phenylpropionaldehyde (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 4us9A

query
sites
4us9A

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding 3-phenylpropanal: 255, 257, 258, 752
binding bicarbonate ion: 460, 498, 531, 532, 535, 539, 890, 892
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 697, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

4us8A Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with benzaldehyde (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 4us8A

query
sites
4us8A

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding bicarbonate ion: 460, 498, 531, 532, 535, 539
binding benzaldehyde: 255, 255, 394, 425, 425, 425, 425, 497, 497, 501, 531, 535, 535, 626, 626, 626, 694, 696, 697
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 653, 654, 655, 656, 695, 696, 697, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

4c7yA Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with sodium dithionite and sodium sulfide (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 4c7yA

query
sites
4c7yA

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F

V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding bicarbonate ion: 460, 498, 531, 535, 539
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869
binding hydrogen peroxide: 696, 697, 869

3fc4A Ethylene glycol inhibited form of aldehyde oxidoreductase from desulfovibrio gigas (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 3fc4A

query
sites
3fc4A

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding 1,2-ethanediol: 535, 622, 696, 697, 869
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 419, 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

3fahA Glycerol inhibited form of aldehyde oxidoreductase from desulfovibrio gigas (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 3fahA

query
sites
3fahA

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding glycerol: 416, 535, 622, 683, 696, 697, 869, 884, 889, 890, 892
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 419, 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

1sijA Crystal structure of the aldehyde dehydrogenase (a.K.A. Aor or mop) of desulfovibrio gigas covalently bound to [aso3]- (see paper)
39% identity, 99% coverage: 3:152/152 of query aligns to 5:158/907 of 1sijA

query
sites
1sijA

I

V

V

I

T

T

I

V

N

N

G

G

V

I

E

E

H

Q

S

N

V

L

D

F

A

V

E

D

A

A

D

E

M

A

P

L

L

L

L

S

W

D

V

V

I

L

R

R

D

Q

L

Q

V

L

G

G

L

L

T

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

V

Q

A
x
G

Q

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

V

V

Y

I

V

L

D

D

G

G

S

K

P

V

V

V

R
|
R

S

A

C
|
C

Q

V

T

T

F

K

I

M

G

K

D

R

I

V

-

A

E

D

G

G

A

A

K

Q

V

I

T

T

I

I

E

E

G

G

L

V

-

G

Q

Q

G

P

K

E

V

N

A

L

E

H

A

P

V

L

Q

Q

A

K

I

A

W

W

A

V

D

L

L

H

D

G

V

G

P

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

S

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

D

G

L

L

V

D

N

T

N

N

P

A

K

D

P

P

S

S

D

R

E

E

D

D

I

V

D

R

A

D

A

W

M

F

S

Q

G

K

-

H

-

R

N

N

L

A

C
|
C

R

R

C
|
C

A

T

T

G

Y

Y

H

K

R

P

I

L

R

V

A

D

G

A

I

V

H

M

E

D

A

A

K

A

R

V

L

I

E

N

G

G

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (≠ A41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), Q99 (= Q95), C100 (= C96), G101 (= G97), C103 (= C99), C137 (= C131), C139 (= C133)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q95), C139 (= C133)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding arsenite: 535, 696, 697, 869
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 653, 654, 655, 656, 695, 696, 698, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

Query Sequence

>WP_015888271.1 NCBI__GCF_000018545.1:WP_015888271.1
MAIVTINGVEHSVDAEADMPLLWVIRDLVGLTGTKFGCGVAQCGACTVYVDGSPVRSCQT
FIGDIEGAKVTTIEGLQGKVAEAVQAIWADLDVPQCGYCQSGQIMSATDLLVNNPKPSDE
DIDAAMSGNLCRCATYHRIRAGIHEAAKRLEG

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory