Comparing WP_017179233.1 NCBI__GCF_000295095.1:WP_017179233.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12) (see 5 papers)
41% identity, 96% coverage: 8:437/448 of query aligns to 4:404/477 of P69786
Sites not aligning to the query:
P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see paper)
44% identity, 95% coverage: 14:437/448 of query aligns to 8:387/648 of P09323
Sites not aligning to the query:
8qsrA Cryo-em structure of the glucose-specific pts transporter iicb from e. Coli in the inward-facing conformation (see paper)
42% identity, 92% coverage: 9:419/448 of query aligns to 2:383/383 of 8qsrA
6bvgA Crystal structure of bcmalt t280c-e54c crosslinked by divalent mercury (see paper)
30% identity, 91% coverage: 14:419/448 of query aligns to 6:442/447 of 6bvgA
>WP_017179233.1 NCBI__GCF_000295095.1:WP_017179233.1
MSQKKKGGAFAAAQRLGRSLMLPIATLPAASLLLRFGQADMLGADGVAKRLSWMQPVADV
LAQAGDAVFSHLPLIFAVGVAVGFAKKSDGSTGVAGLFGYLVLEGVLKALAPYLGAGGDG
DPAKSTINYGVLGGIIIGITAALLWQRFYRIKLPDWLAFFGGRRFVPIITSLAALAIGVV
LALIYPAFNWLINEQLGGWLMEAGTKGGAAAVIASFVFGTINRLLIPFGLHHLLNSIPWF
QLGDCTNASGQTVHGDLTCFFSGVDGTNAWTGSFMTGFFPIMMFALPGAALAIWRTARPE
KRKATGALMASVALTAFVTGITEPLEYAFAYVAFPLYAIHAVLTGTSLALVNALGIKDGF
GFSAGGIDYLLNFGKSADLSAQGVMGPVLLVVIGLAYALVYYALFRFLIIRLGFATPGRE
EDETDAFSAAQSAAAESTGKKAPGEQRR
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory