Comparing WP_017597380.1 NCBI__GCF_000341125.1:WP_017597380.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P00897 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Serratia marcescens (see paper)
31% identity, 91% coverage: 41:455/457 of query aligns to 31:450/519 of P00897
Sites not aligning to the query:
1i7qA Anthranilate synthase from s. Marcescens (see paper)
31% identity, 91% coverage: 41:455/457 of query aligns to 29:448/517 of 1i7qA
Sites not aligning to the query:
1i7sA Anthranilate synthase from serratia marcescens in complex with its end product inhibitor l-tryptophan (see paper)
32% identity, 86% coverage: 61:455/457 of query aligns to 43:442/511 of 1i7sA
Sites not aligning to the query:
P00898 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
30% identity, 91% coverage: 41:456/457 of query aligns to 32:452/520 of P00898
Sites not aligning to the query:
1i1qA Structure of the cooperative allosteric anthranilate synthase from salmonella typhimurium (see paper)
30% identity, 91% coverage: 41:456/457 of query aligns to 28:448/512 of 1i1qA
Sites not aligning to the query:
7bvdA Anthranilate synthase component i (trpe)[mycolicibacterium smegmatis]
38% identity, 45% coverage: 251:455/457 of query aligns to 230:431/499 of 7bvdA
Sites not aligning to the query:
A0QX93 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
38% identity, 45% coverage: 251:455/457 of query aligns to 251:456/524 of A0QX93
O94582 Probable anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
31% identity, 66% coverage: 157:456/457 of query aligns to 107:415/489 of O94582
Sites not aligning to the query:
P28820 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Bacillus subtilis (strain 168) (see paper)
32% identity, 66% coverage: 153:455/457 of query aligns to 97:401/470 of P28820
Q94GF1 Anthranilate synthase alpha subunit 1, chloroplastic; OsASA1; EC 4.1.3.27 from Oryza sativa subsp. japonica (Rice) (see paper)
37% identity, 45% coverage: 251:456/457 of query aligns to 291:491/577 of Q94GF1
7pi1DDD Aminodeoxychorismate synthase component 1
31% identity, 66% coverage: 153:455/457 of query aligns to 95:394/459 of 7pi1DDD
Sites not aligning to the query:
5cwaA Structure of anthranilate synthase component i (trpe) from mycobacterium tuberculosis with inhibitor bound (see paper)
37% identity, 45% coverage: 251:455/457 of query aligns to 230:435/505 of 5cwaA
Sites not aligning to the query:
P32068 Anthranilate synthase alpha subunit 1, chloroplastic; Anthranilate synthase component 1-1; Anthranilate synthase component I-1; Protein A-METHYL TRYPTOPHAN RESISTANT 1; Protein JASMONATE-INDUCED DEFECTIVE LATERAL ROOT 1; Protein TRYPTOPHAN BIOSYNTHESIS 5; Protein WEAK ETHYLENE INSENSITIVE 2; EC 4.1.3.27 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
29% identity, 66% coverage: 157:456/457 of query aligns to 192:509/595 of P32068
8hx9A Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae with chorismate (see paper)
29% identity, 71% coverage: 131:455/457 of query aligns to 235:572/632 of 8hx9A
Sites not aligning to the query:
8hx8A Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
29% identity, 71% coverage: 131:455/457 of query aligns to 277:611/673 of 8hx8A
Sites not aligning to the query:
P05041 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Escherichia coli (strain K12) (see 4 papers)
26% identity, 66% coverage: 157:457/457 of query aligns to 105:395/453 of P05041
Sites not aligning to the query:
1k0eA The crystal structure of aminodeoxychorismate synthase from formate grown crystals (see paper)
26% identity, 66% coverage: 157:457/457 of query aligns to 103:379/437 of 1k0eA
Sites not aligning to the query:
5jy9B An iron-bound structure of the salicylate synthase irp9 (see paper)
27% identity, 68% coverage: 148:456/457 of query aligns to 81:365/424 of 5jy9B
Sites not aligning to the query:
2fn1A Crystal structures of yersinia enterocolitica salicylate synthase (irp9) in complex with the reaction products salicylate and pyruvate (see paper)
29% identity, 45% coverage: 250:456/457 of query aligns to 148:349/408 of 2fn1A
Sites not aligning to the query:
2fn0A Crystal structure of yersinia enterocolitica salicylate synthase (irp9) (see paper)
29% identity, 45% coverage: 250:456/457 of query aligns to 148:349/408 of 2fn0A
Sites not aligning to the query:
>WP_017597380.1 NCBI__GCF_000341125.1:WP_017597380.1
MNSSDASTTTYRTQGGVTVRRTAADCDPELLTDLVRSVEHRRGGVLSSGMEYPGRYDRWH
LGYVDPCLEVIARGRRVTATALNARGRVLLPVVADALVSVGAGQDREADADHVAVTVPEP
DAGEFFTEEERSRRPSVFTAVRAVIAAMSSPEDANLGLYGAFGYDLAFQFEPIEAHIDRD
PGDRDLVLHLPDAIVVRDRKRETCVRYTYEFTVPADGDRPEASTDGLERVTEPTPRVVAA
EVPEGPEPGSYARVVAEAKEKFRRGDLFEVVPGHRTYARCSSPARFYELLRERNPAPYEF
FFNLGEGEYLVGASPEMFVRVTGEPGTGQRVETCPISGTISRGEDALGDAENIQELLSSV
KEKSELTMCTDVDRNDKSRVCEPGSVRVIGRRQIEMYSRLIHTVDHIEGTLRRDFDALDA
FLTHMWAVTVTGAPKTWAMRFIERHETSPRRWYGGGG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory