Comparing WP_018125987.1 NCBI__GCF_000375485.1:WP_018125987.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
37% identity, 98% coverage: 9:351/351 of query aligns to 6:342/342 of 2ozpA
O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
37% identity, 98% coverage: 9:351/351 of query aligns to 8:344/344 of O50146
5einA Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
36% identity, 98% coverage: 9:351/351 of query aligns to 8:344/344 of 5einA
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
37% identity, 98% coverage: 9:351/351 of query aligns to 9:347/347 of 2i3gA
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
37% identity, 98% coverage: 9:351/351 of query aligns to 6:344/344 of 7npjB
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
37% identity, 98% coverage: 9:351/351 of query aligns to 6:344/344 of 7nphC
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
37% identity, 98% coverage: 9:351/351 of query aligns to 6:344/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
37% identity, 98% coverage: 9:351/351 of query aligns to 6:344/344 of 7nnrA
4dpmA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with coa (see paper)
24% identity, 91% coverage: 4:322/351 of query aligns to 2:333/354 of 4dpmA
4dplA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with NADP (see paper)
24% identity, 91% coverage: 4:322/351 of query aligns to 2:333/354 of 4dplA
Sites not aligning to the query:
4dpkA Structure of malonyl-coenzyme a reductase from crenarchaeota (see paper)
24% identity, 91% coverage: 4:322/351 of query aligns to 2:333/354 of 4dpkA
Q57658 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
25% identity, 94% coverage: 2:332/351 of query aligns to 6:346/354 of Q57658
1ys4A Structure of aspartate-semialdehyde dehydrogenase from methanococcus jannaschii (see paper)
25% identity, 93% coverage: 5:332/351 of query aligns to 3:340/348 of 1ys4A
3hskA Crystal structure of aspartate semialdehyde dehydrogenase with NADP from candida albicans (see paper)
32% identity, 29% coverage: 7:108/351 of query aligns to 5:111/358 of 3hskA
4zicC Crystal structure of aspartate semialdehyde dehydrogenase with NADP from trichophyton rubrum (see paper)
31% identity, 29% coverage: 8:109/351 of query aligns to 5:110/357 of 4zicC
Sites not aligning to the query:
>WP_018125987.1 NCBI__GCF_000375485.1:WP_018125987.1
MKGTIAAGLVGVTGYAGMELARLMTSHPSMELVRVTSRAEAGKKLSDLYPFLQGLGPGEL
EVTEPDPRDLATSCDVVFLAVPHKAAMEIAAVLLEEGVKVVDLSADFRLRDRCTYEQWYD
VPHTRPELLEQAVYGLPELYADRIPLANLIANPGCYPTASVLGLAPALKNGLVETDGVII
DAKSGASGAGRGAKVPNLFCEVHDSFRAYGLPKHRHTPEIEQEAGLLAGTDMVLSFNTHL
LPIDRGILATIYTSLKDGVTMEAVREAYESFYADKPYVRVLPEGKFPETRFVRGTMFCDI
GLVTDPRTGRLIILSAIDNLCRGASGQALANANLMCGLDISLGLPTAPLMP
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory