SitesBLAST
Comparing WP_018371667.1 NCBI__GCF_000341525.1:WP_018371667.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7omlA Bacillus subtilis phosphoglucomutase glmm (metal bound) (see paper)
63% identity, 99% coverage: 2:448/450 of query aligns to 1:445/445 of 7omlA
7ojrA Bacillus subtilis phosphoglucomutase glmm (phosphate bound) (see paper)
63% identity, 99% coverage: 2:448/450 of query aligns to 1:445/445 of 7ojrA
P31120 Phosphoglucosamine mutase; EC 5.4.2.10 from Escherichia coli (strain K12) (see 3 papers)
44% identity, 99% coverage: 3:446/450 of query aligns to 5:445/445 of P31120
- S100 (= S99) mutation to A: 2% of wild-type activity.; mutation to T: 20-fold increase in the non-specific phosphoglucomutase activity towards glucose-phosphate substrates (non aminated).
- S102 (= S101) active site, Phosphoserine intermediate; modified: Phosphoserine; by autocatalysis; mutation to A: Loss of activity in the absence or presence of glucosamine-1,6-diP.
Sites not aligning to the query:
- 1 modified: Initiator methionine, Removed
3i3wA Structure of a phosphoglucosamine mutase from francisella tularensis
39% identity, 97% coverage: 3:439/450 of query aligns to 1:436/441 of 3i3wA
- active site: R9 (= R11), S99 (= S101), H100 (= H102), K109 (= K111), D237 (= D240), D239 (= D242), D241 (= D244), R242 (= R245), H324 (= H329)
- binding zinc ion: S99 (= S101), D237 (= D240), D239 (= D242), D241 (= D244)
1wqaA Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
34% identity, 97% coverage: 1:437/450 of query aligns to 1:444/455 of 1wqaA
- active site: R11 (= R11), S101 (= S101), H102 (= H102), K111 (= K111), D243 (= D240), D245 (= D242), D247 (= D244), R248 (= R245), G330 (≠ H329), R340 (≠ G339)
- binding magnesium ion: S101 (= S101), D243 (= D240), D245 (= D242), D247 (= D244)
1pcjX Enzyme-ligand complex of p. Aeruginosa pmm/pgm (see paper)
28% identity, 97% coverage: 10:445/450 of query aligns to 14:445/458 of 1pcjX
- active site: R15 (= R11), S103 (= S101), H104 (= H102), K113 (= K111), D237 (= D240), D239 (= D242), D241 (= D244), R242 (= R245), H324 (= H329), D335 (≠ G339)
- binding 1-O-phosphono-alpha-D-mannopyranose: S103 (= S101), T301 (≠ V306), G302 (= G307), E320 (= E325), S322 (= S327), H324 (= H329), R416 (= R412), S418 (= S414), N419 (≠ G415), T420 (= T416)
- binding zinc ion: S103 (= S101), D237 (= D240), D239 (= D242), D241 (= D244)
Sites not aligning to the query:
2h5aX Complex of the enzyme pmm/pgm with xylose 1-phosphate (see paper)
28% identity, 97% coverage: 10:445/450 of query aligns to 11:442/455 of 2h5aX
- active site: H101 (= H102), D234 (= D240), D236 (= D242), D238 (= D244), R239 (= R245), D332 (≠ G339)
- binding 1-O-phosphono-alpha-D-xylopyranose: T298 (≠ V306), G299 (= G307), H300 (≠ D308), E317 (= E325), S319 (= S327), H321 (= H329), R413 (= R412), S415 (= S414), N416 (≠ G415), T417 (= T416)
- binding zinc ion: S100 (= S101), D234 (= D240), D236 (= D242), D238 (= D244)
Sites not aligning to the query:
2h4lX Complex of pmm/pgm with ribose 1-phosphate (see paper)
28% identity, 97% coverage: 10:445/450 of query aligns to 11:442/455 of 2h4lX
- active site: H101 (= H102), D234 (= D240), D236 (= D242), D238 (= D244), R239 (= R245), D332 (≠ G339)
- binding 1-O-phosphono-alpha-D-ribofuranose: R12 (= R11), S100 (= S101), T298 (≠ V306), E317 (= E325), R413 (= R412), S415 (= S414), N416 (≠ G415), T417 (= T416)
- binding zinc ion: S100 (= S101), D234 (= D240), D236 (= D242), D238 (= D244)
Sites not aligning to the query:
2fkfA Phosphomannomutase/phosphoglucomutase from pseudomonas aeruginosa with alpha-d-glucose 1,6-bisphosphate bound (see paper)
28% identity, 97% coverage: 10:445/450 of query aligns to 11:442/455 of 2fkfA
- active site: R12 (= R11), S100 (= S101), H101 (= H102), K110 (= K111), D234 (= D240), D236 (= D242), D238 (= D244), R239 (= R245), H321 (= H329), D332 (≠ G339)
- binding 1,6-di-O-phosphono-alpha-D-glucopyranose: H101 (= H102), S319 (= S327), R413 (= R412), S415 (= S414), N416 (≠ G415), T417 (= T416)
- binding zinc ion: S100 (= S101), D234 (= D240), D236 (= D242), D238 (= D244)
Sites not aligning to the query:
1pcmX Enzyme-ligand complex of p. Aeruginosa pmm/pgm (see paper)
28% identity, 97% coverage: 10:445/450 of query aligns to 11:442/455 of 1pcmX
- active site: R12 (= R11), S100 (= S101), H101 (= H102), K110 (= K111), D234 (= D240), D236 (= D242), D238 (= D244), R239 (= R245), H321 (= H329), D332 (≠ G339)
- binding 6-O-phosphono-alpha-D-mannopyranose: S100 (= S101), T298 (≠ V306), G299 (= G307), H300 (≠ D308), E317 (= E325), S319 (= S327), H321 (= H329), R413 (= R412), S415 (= S414)
- binding zinc ion: S100 (= S101), D234 (= D240), D236 (= D242), D238 (= D244)
Sites not aligning to the query:
1p5gX Enzyme-ligand complex of p. Aeruginosa pmm/pgm (see paper)
28% identity, 97% coverage: 10:445/450 of query aligns to 11:442/455 of 1p5gX