Comparing WP_019557049.1 NCBI__GCF_000381085.1:WP_019557049.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 13 hits to proteins with known functional sites (download)
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
38% identity, 99% coverage: 6:349/349 of query aligns to 2:344/344 of 7npjB
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
38% identity, 99% coverage: 6:349/349 of query aligns to 2:344/344 of 7nphC
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
38% identity, 99% coverage: 6:349/349 of query aligns to 2:344/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
38% identity, 99% coverage: 6:349/349 of query aligns to 2:344/344 of 7nnrA
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
38% identity, 99% coverage: 6:349/349 of query aligns to 5:347/347 of 2i3gA
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
37% identity, 99% coverage: 5:349/349 of query aligns to 1:342/342 of 2ozpA
O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
37% identity, 99% coverage: 4:349/349 of query aligns to 2:344/344 of O50146
5einA Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
37% identity, 99% coverage: 4:349/349 of query aligns to 2:344/344 of 5einA
Q04797 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Bacillus subtilis (strain 168) (see paper)
23% identity, 93% coverage: 6:328/349 of query aligns to 5:335/346 of Q04797
Q57658 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
24% identity, 53% coverage: 5:188/349 of query aligns to 8:190/354 of Q57658
Sites not aligning to the query:
1ys4A Structure of aspartate-semialdehyde dehydrogenase from methanococcus jannaschii (see paper)
24% identity, 53% coverage: 5:188/349 of query aligns to 2:184/348 of 1ys4A
Sites not aligning to the query:
P23247 Aspartate-semialdehyde dehydrogenase 2; ASA dehydrogenase 2; ASADH 2; Aspartate-beta-semialdehyde dehydrogenase 2; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
24% identity, 59% coverage: 3:207/349 of query aligns to 2:183/337 of P23247
2r00C Crystal structure of aspartate semialdehyde dehydrogenase ii complexed with asa from vibrio cholerae (see paper)
24% identity, 59% coverage: 3:207/349 of query aligns to 1:182/336 of 2r00C
Sites not aligning to the query:
>WP_019557049.1 NCBI__GCF_000381085.1:WP_019557049.1
MTNQKVQVGIVGGTGYTGVELLRSLANHPFAEVTMITSRSEQGVAVADMYPNLRGIYRLQ
FSVPDIEKLKNCDLVFFATPHGVATSMAFELIEAGVKVIDLAADFRIEDLAVWQKWYGIE
PASEALMAEAVYGLPEYYREKIKHAKVIANPGCYPTSILLGILPLLKADLVKVDSIIADG
KSGVSGAGKGASVAMLGAEMSESFKAYGVNGHRHLPEMQEKMSLLTGQEVGLTFVPHLLP
MVRGMESTIYATLKIDKTQAELQALYEAAYENEPFVDVMPAGSLPETRMVKGSNMCRMAI
YCPPGGNIVVITSVIDNLVKGAAGQAIQNMNIMFNLPETAGLNQVALLP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory