Comparing WP_020173422.1 NCBI__GCF_000385335.1:WP_020173422.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 14 hits to proteins with known functional sites (download)
1v72A Crystal structure of phenylserine aldolase from pseudomonas putida
44% identity, 98% coverage: 1:347/355 of query aligns to 5:338/345 of 1v72A
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
39% identity, 86% coverage: 3:309/355 of query aligns to 6:310/344 of 5vyeB
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
39% identity, 86% coverage: 3:309/355 of query aligns to 8:312/346 of O50584
1jg8D Crystal structure of threonine aldolase (low-specificity)
27% identity, 51% coverage: 1:181/355 of query aligns to 3:179/344 of 1jg8D
Sites not aligning to the query:
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
27% identity, 51% coverage: 1:181/355 of query aligns to 2:178/343 of 1lw5B
Sites not aligning to the query:
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
27% identity, 51% coverage: 1:181/355 of query aligns to 2:178/343 of 1lw4B
Sites not aligning to the query:
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
27% identity, 71% coverage: 30:280/355 of query aligns to 32:273/338 of O07051
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
27% identity, 71% coverage: 30:280/355 of query aligns to 31:272/333 of 3wgcB
Sites not aligning to the query:
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
26% identity, 80% coverage: 30:313/355 of query aligns to 30:303/324 of 3wgbD
Sites not aligning to the query:
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
28% identity, 52% coverage: 1:185/355 of query aligns to 2:180/331 of 3wlxA
Sites not aligning to the query:
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
27% identity, 52% coverage: 1:185/355 of query aligns to 2:180/332 of 4rjyA
Sites not aligning to the query:
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
27% identity, 52% coverage: 1:185/355 of query aligns to 2:180/332 of 4lnlA
Sites not aligning to the query:
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
27% identity, 52% coverage: 1:185/355 of query aligns to 2:180/332 of 4lnjA
Sites not aligning to the query:
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
27% identity, 52% coverage: 1:185/355 of query aligns to 2:180/331 of 4lnmA
Sites not aligning to the query:
>WP_020173422.1 NCBI__GCF_000385335.1:WP_020173422.1
MDFTSDNTFGAHPKILEAIVATNSGPVASYGEDPFTQKAAARLSEIFEHETSVFFVATGT
AANALALGAVCPPWGAVFCHEDAHISEDECGAPEMFTAGAKIVGIPGFAGKISTANFKKA
LASFPRGQVKQVQPAVLSLSQLTEAGTAYACEDIASLAALAHEAGLKVHMDGARFANALV
AQNCSPAAMSWQAGIDVLSLGATKNGALACEAVIFFDPAMAEAFAYQRKRSGHTVSKGRF
LGAQMLAYLDAGLWLGLAKIANDHAARLAAGLAKIPGVRLPWLPDANEIFVIIPGAIDNR
LKAAGAAYYEWGLRDYPPEVIPPSEGEVFVRLVTSYATASADIDRLIAIAQGIAK
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory