Comparing WP_025272347.1 NCBI__GCF_000527155.1:WP_025272347.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5dx5A Crystal structure of methionine gamma-lyase from clostridium sporogenes (see paper)
41% identity, 98% coverage: 7:379/380 of query aligns to 10:394/399 of 5dx5A
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
40% identity, 98% coverage: 7:379/380 of query aligns to 10:392/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
40% identity, 98% coverage: 7:379/380 of query aligns to 10:392/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
40% identity, 98% coverage: 7:379/380 of query aligns to 10:392/396 of 3jwaA
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine (see paper)
40% identity, 98% coverage: 7:379/380 of query aligns to 10:392/396 of 3jw9A
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine (see paper)
40% identity, 98% coverage: 7:379/380 of query aligns to 9:391/395 of 5m3zA
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
40% identity, 98% coverage: 7:379/380 of query aligns to 10:392/396 of 4hf8A
6egrA Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
39% identity, 98% coverage: 7:379/380 of query aligns to 10:392/396 of 6egrA
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate (see paper)
40% identity, 87% coverage: 50:379/380 of query aligns to 15:381/386 of 3mkjA
1e5fA Methionine gamma-lyase (mgl) from trichomonas vaginalis
37% identity, 98% coverage: 7:379/380 of query aligns to 7:389/393 of 1e5fA
1e5eA Methionine gamma-lyase (mgl) from trichomonas vaginalis in complex with propargylglycine
37% identity, 98% coverage: 7:379/380 of query aligns to 7:389/394 of 1e5eA
7d7oB Crystal structure of cystathionine gamma-lyase from bacillus cereus atcc 14579 (see paper)
40% identity, 84% coverage: 60:379/380 of query aligns to 44:376/377 of 7d7oB
1pg8A Crystal structure of l-methionine alpha-, gamma-lyase
38% identity, 98% coverage: 7:379/380 of query aligns to 12:394/398 of 1pg8A
P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
38% identity, 98% coverage: 7:379/380 of query aligns to 12:394/398 of P13254
5x2xA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-homocysteine intermediates (see paper)
38% identity, 98% coverage: 7:379/380 of query aligns to 6:388/392 of 5x2xA
5x2wA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-methionine intermediates (see paper)
38% identity, 98% coverage: 7:379/380 of query aligns to 6:388/392 of 5x2wA
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine (see paper)
38% identity, 98% coverage: 7:379/380 of query aligns to 11:393/397 of 3vk3A
5x30C Crystal structure of pseudomonas putida methionine gamma-lyase c116h mutant with l-homocysteine intermediates. (see paper)
38% identity, 98% coverage: 7:379/380 of query aligns to 7:389/393 of 5x30C
7mcyH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl3 (see paper)
40% identity, 84% coverage: 60:379/380 of query aligns to 45:377/380 of 7mcyH
Sites not aligning to the query:
7mcuH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl2 (see paper)
40% identity, 84% coverage: 60:379/380 of query aligns to 45:377/380 of 7mcuH
Sites not aligning to the query:
>WP_025272347.1 NCBI__GCF_000527155.1:WP_025272347.1
MTDDLFTRAVHAGREDLLEAGVHVPPIDLSTTYPAVDSAAEAERMDQYAAGQQPDGSPIY
ARLHNPTVARFEKALAELEHSEAAVAFASGMAAMSASLLAATSGGKREIVAVRPVYGGTD
LVLSTGLLGTEVTWTDADSVADAITSNTALVIVETPANPTLHELSIRDIATACGDVPLLV
DNTLATPALQNPIREGASIALHSATKALGGYGDVVGGVVACDEAFAQKMRSVRIATGGVL
HPLAAYMLQRGLATLPLRVERMSRTAHDLAVRLQDDPRVSAVHYPGLNSNRPSQMTSGGT
MVSFETTEDARDVIKKVSLITPAVSLGSVDSLIQHPASLTHHVVDPDARETCGISDHLIR
LSVGLESPDDLWADLDTALG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory