Comparing WP_028319971.1 NCBI__GCF_000422285.1:WP_028319971.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3dc2A Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis (see paper)
36% identity, 100% coverage: 3:526/526 of query aligns to 4:525/526 of 3dc2A
3ddnB Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis (see paper)
36% identity, 100% coverage: 3:526/526 of query aligns to 5:524/525 of 3ddnB
O43175 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) (see 3 papers)
43% identity, 76% coverage: 2:403/526 of query aligns to 8:409/533 of O43175
Sites not aligning to the query:
6cwaA Crystal structure phgdh in complex with nadh and 3-phosphoglycerate at 1.77 a resolution (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 2:297/299 of 6cwaA
7ewhA Crystal structure of human phgdh in complex with homoharringtonine (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 3:298/302 of 7ewhA
6rihA Crystal structure of phgdh in complex with compound 9 (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 3:298/302 of 6rihA
6rj5A Crystal structure of phgdh in complex with compound 39 (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 3:298/301 of 6rj5A
6plgA Crystal structure of human phgdh complexed with compound 15 (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 3:298/303 of 6plgA
6rj3A Crystal structure of phgdh in complex with compound 15 (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 2:297/297 of 6rj3A
7dkmA Phgdh covalently linked to oridonin (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 4:299/306 of 7dkmA
6plfA Crystal structure of human phgdh complexed with compound 1 (see paper)
49% identity, 56% coverage: 2:298/526 of query aligns to 4:299/305 of 6plfA
6rj2A Crystal structure of phgdh in complex with compound 40 (see paper)
49% identity, 56% coverage: 3:298/526 of query aligns to 1:295/299 of 6rj2A
6plfB Crystal structure of human phgdh complexed with compound 1 (see paper)
47% identity, 56% coverage: 2:298/526 of query aligns to 2:289/292 of 6plfB
7cvpA The crystal structure of human phgdh from biortus.
42% identity, 56% coverage: 2:298/526 of query aligns to 2:252/254 of 7cvpA
1wwkA Crystal structure of phosphoglycerate dehydrogenase from pyrococcus horikoshii ot3
40% identity, 57% coverage: 1:302/526 of query aligns to 1:302/304 of 1wwkA
6rj6A Crystal structure of phgdh in complex with bi-4924 (see paper)
47% identity, 38% coverage: 98:298/526 of query aligns to 3:203/204 of 6rj6A
5ofwA Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-chloro-4-fluorobenzamide (see paper)
49% identity, 37% coverage: 96:287/526 of query aligns to 2:193/195 of 5ofwA
5ofvA Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-fluoro-2-methylbenzoic acid (see paper)
49% identity, 37% coverage: 96:287/526 of query aligns to 2:193/195 of 5ofvA
5ofmA Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-amino-1-methyl-1h-indole
49% identity, 37% coverage: 96:287/526 of query aligns to 2:193/195 of 5ofmA
5nzqA Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-(1,3-oxazol-5-yl)aniline. (see paper)
49% identity, 37% coverage: 96:287/526 of query aligns to 2:193/195 of 5nzqA
>WP_028319971.1 NCBI__GCF_000422285.1:WP_028319971.1
MKVLISDPMSEIGIKVLEETPGIDVDVNTGLTPEELKGIIGQYHGLAIRSATKVTADIIA
AATQLKVIGRAGIGLDNVDIPAASQRGIVVMNTPEGNTITTAEHTIAMMMALTRNIPQAT
GSLREGKWEKKKLKGREVFNKTLGLIGAGHIGRIVADRAKGLKMKVIVYDPYIKPESIEK
MDLEPVSFDELLQRSDYVTIHTPKTNETVNMFNADTFARMKKGAMLINCARGGIVNEADL
YDALVSGQLGGAALDVFASEPPGANKLLELPTFICTPHLGASTTEAQDNVAKDVAEQIAA
YLLHGSVKNAVNVPSISSELMSILRPYVTLVERMGALQSQLAESAVLEVKIHYAGAVSQY
DMAPLTTAVLKGLLTPILKDDVNFVNAPYIASERGIKVVESKSQTSEDFASLVALTVKTL
EGENIVSGTIFGKDRPRILRINNFYMEAIPEGHILLIQNQDSPGVIGQIGMTLGKFGLNI
SRMHVGEEKEKKQNVIILTTSTIVNDDVLEALRGLPNVFAVKRIEL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory