Comparing WP_028486581.1 NCBI__GCF_000483485.1:WP_028486581.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
41% identity, 97% coverage: 17:491/491 of query aligns to 17:495/496 of 8g1yA
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
35% identity, 87% coverage: 1:428/491 of query aligns to 2:416/464 of 4f4fA
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 90% coverage: 1:440/491 of query aligns to 5:467/514 of Q42598
1kl7A Crystal structure of threonine synthase from yeast (see paper)
31% identity, 88% coverage: 7:440/491 of query aligns to 8:464/509 of 1kl7A
1vb3A Crystal structure of threonine synthase from escherichia coli
31% identity, 79% coverage: 16:405/491 of query aligns to 12:360/428 of 1vb3A
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine (see paper)
23% identity, 67% coverage: 99:429/491 of query aligns to 112:404/444 of 2c2bA
Sites not aligning to the query:
Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
23% identity, 67% coverage: 99:429/491 of query aligns to 187:479/526 of Q9S7B5
Sites not aligning to the query:
2c2gA Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
23% identity, 67% coverage: 99:429/491 of query aligns to 130:406/448 of 2c2gA
>WP_028486581.1 NCBI__GCF_000483485.1:WP_028486581.1
MNFTETRGNDGQFPLEMTFSQAILSPMSSFGGLYSPKSLPDLGLPFLEKHLQSDYKTLAT
AILAEFEVDIEQSIIDEALSLYDQFDDPQNPVPVVKVRDDLYVSELYHGPTRAFKDMALQ
PFGTVLSAIAKARNEKYLILAATSGDTGPAALDTFRNRENVQVACLYPEGGTSDVQRLQM
VTENAPNLKVIGIKGDFDDAQSALKKLLTSDSFKAKLQENQISLSAANSVNFGRIIFQTI
YHLHSYLELIRQGAIQMGEKVYLNVPSGNFGNALGGYYAFKMGLPVEKILIASNSNNVLT
QFIQTGVYDLRDLNVIPTSSPAMDILKSSNIERILFDLFGAQRTKELMLALDKEKHYALT
QSELAEIQAVFSADFCTDDEGEAYIKQAFSEGYLMDPHTATCFKSYDTCRQHPELKTIVY
STAEWTKFSPIIANALTGKSGLHDIEALKVISEQAGVSIPAKIQKLFETEISQSTVIDKR
DIEQEILNFLG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory