Comparing WP_028487974.1 NCBI__GCF_000621325.1:WP_028487974.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
42% identity, 87% coverage: 31:252/255 of query aligns to 38:245/252 of 3qdfA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
34% identity, 98% coverage: 3:253/255 of query aligns to 3:273/277 of 6iymA
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
35% identity, 89% coverage: 25:252/255 of query aligns to 32:264/269 of 4dbhA
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
34% identity, 84% coverage: 41:255/255 of query aligns to 77:302/303 of 8sutA
O06724 Oxaloacetate tautomerase YisK; Oxaloacetate decarboxylase YisK; EC 5.3.2.2; EC 4.1.1.112 from Bacillus subtilis (strain 168) (see paper)
34% identity, 84% coverage: 41:255/255 of query aligns to 76:301/301 of O06724
Sites not aligning to the query:
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
34% identity, 84% coverage: 41:255/255 of query aligns to 76:301/303 of 8skyB
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
32% identity, 78% coverage: 54:253/255 of query aligns to 67:275/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
32% identity, 78% coverage: 54:253/255 of query aligns to 67:275/280 of 6j5xA
Q6P587 Oxaloacetate tautomerase FAHD1, mitochondrial; Acylpyruvase FAHD1; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; ODx; YisK-like protein; EC 5.3.2.2; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 4 papers)
34% identity, 69% coverage: 77:251/255 of query aligns to 37:213/221 of Q6P587
Sites not aligning to the query:
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
34% identity, 68% coverage: 78:251/255 of query aligns to 36:211/218 of 6fogA
Sites not aligning to the query:
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
28% identity, 90% coverage: 2:231/255 of query aligns to 6:247/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
28% identity, 90% coverage: 2:231/255 of query aligns to 6:247/290 of 8gsrA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
32% identity, 79% coverage: 54:254/255 of query aligns to 69:275/279 of 6v77B
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
31% identity, 83% coverage: 40:250/255 of query aligns to 61:256/264 of 6jvwB
Q1NEI7 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase; L-2,4-diketo-3-deoxyrhamnonate hydrolase; L-DKDR hydrolase; SpLRA6; EC 3.7.1.26 from Sphingomonas sp. (strain SKA58) (see paper)
30% identity, 69% coverage: 56:231/255 of query aligns to 67:242/285 of Q1NEI7
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
34% identity, 67% coverage: 77:247/255 of query aligns to 34:206/216 of 6sbiA
Sites not aligning to the query:
Q8R0F8 Oxaloacetate tautomerase FAHD1, mitochondrial; Acylpyruvase FAHD1; Acylpyruvate hydrolase; ApH; Fumarylacetoacetate hydrolase domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; ODx; EC 5.3.2.2; EC 3.7.1.5; EC 4.1.1.112 from Mus musculus (Mouse) (see paper)
34% identity, 70% coverage: 77:254/255 of query aligns to 37:214/221 of Q8R0F8
Sites not aligning to the query:
1gttA Crystal structure of hpce (see paper)
36% identity, 70% coverage: 76:254/255 of query aligns to 236:414/421 of 1gttA
P76004 Oxaloacetate tautomerase YcgM; EC 5.3.2.2 from Escherichia coli (strain K12)
28% identity, 78% coverage: 55:253/255 of query aligns to 17:217/219 of P76004
6j5yA Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
30% identity, 69% coverage: 79:253/255 of query aligns to 49:229/233 of 6j5yA
Sites not aligning to the query:
>WP_028487974.1 NCBI__GCF_000621325.1:WP_028487974.1
MAQWVRFTAEGETRFGTLAHGIITEYTGDMFAGSTLSGREFALAAVKLLRPCEPSKLIGL
WNNFQERAVVENLHKPDHPLYFLKAANSFAADGELIPRPAGYSGMVVFEGELGIVIGKRC
KGIALEQAPEYIFGYTCVNDVTARELLKLDPAFVHWTRAKSFDQFGVFGPSIATGLDPAT
LRVRVELNGVEKQNYPVADMFFSPYEIVSRISHDMTLEAGDVIACGTSVGVCGMADGDTV
VVSIAGVGELTNRFG
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory