Comparing WP_028990559.1 NCBI__GCF_000423825.1:WP_028990559.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4grsA Crystal structure of a chimeric dah7ps (see paper)
35% identity, 93% coverage: 1:352/377 of query aligns to 1:326/333 of 4grsA
3pg9A Thermotoga maritima dah7p synthase in complex with inhibitor (see paper)
35% identity, 94% coverage: 1:355/377 of query aligns to 1:332/338 of 3pg9A
1rzmA Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahps) from thermotoga maritima complexed with cd2+, pep and e4p (see paper)
35% identity, 94% coverage: 1:355/377 of query aligns to 1:332/338 of 1rzmA
1zcoB Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase (see paper)
39% identity, 72% coverage: 83:352/377 of query aligns to 5:255/262 of 1zcoB
1zcoA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase (see paper)
39% identity, 72% coverage: 83:352/377 of query aligns to 5:255/262 of 1zcoA
4c1kA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase (see paper)
38% identity, 72% coverage: 83:352/377 of query aligns to 5:255/262 of 4c1kA
5j6fA Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
37% identity, 70% coverage: 89:352/377 of query aligns to 103:348/352 of 5j6fA
Sites not aligning to the query:
1vs1D Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase) from aeropyrum pernix in complex with mn2+ and pep
39% identity, 74% coverage: 79:356/377 of query aligns to 10:269/271 of 1vs1D
P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168) (see paper)
36% identity, 73% coverage: 78:352/377 of query aligns to 94:350/358 of P39912
Sites not aligning to the query:
3nvtA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
34% identity, 72% coverage: 78:348/377 of query aligns to 82:334/345 of 3nvtA
3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate (see paper)
34% identity, 72% coverage: 78:348/377 of query aligns to 81:333/343 of 3tfcA
2nx3D Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
25% identity, 56% coverage: 141:352/377 of query aligns to 47:248/262 of 2nx3D
Sites not aligning to the query:
3e0iA Cu2+ substituted aquifex aeolicus kdo8ps in complex with pep (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:249/263 of 3e0iA
2a21A Aquifex aeolicus kdo8ps in complex with pep, po4, and zn2+ (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:249/263 of 2a21A
1jcyA Aquifex aeolicus kdo8p synthase in complex with r5p, pep and cadmium (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:249/263 of 1jcyA
1fwwA Aquifex aeolicus kdo8p synthase in complex with pep, a5p and cadmium (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:249/263 of 1fwwA
1fwtA Aquifex aeolicus kdo8p synthase in complex with pep, e4p and cadmium (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:249/263 of 1fwtA
1jcxA Aquifex aeolicus kdo8p synthase in complex with api and cadmium (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:241/255 of 1jcxA
3e12A Cu2+ substituted aquifex aeolicus kdo8ps in complex with kdo8p (see paper)
23% identity, 67% coverage: 101:352/377 of query aligns to 1:244/258 of 3e12A
1gg0A Crystal structure analysis of kdop synthase at 3.0 a (see paper)
31% identity, 30% coverage: 237:350/377 of query aligns to 150:256/275 of 1gg0A
Sites not aligning to the query:
>WP_028990559.1 NCBI__GCF_000423825.1:WP_028990559.1
MILILAPNIDQNSPEYRQLMDYVSKLPKIQARVHQEHGAQQVLTEVYLVGDTASLSVEDM
KSLPCVERVVRVSEEYRVLGRHKDDQRPTAFEYNGVRFGQDNLNVFAGLCAVDTPEHVEL
MMKALREHGQVCTRMGAYKPRTNPYSFQGHGKACLPYVFELAGKYGIRVIAMEITHEAHV
DEIREALRQTGNPTGVMLQIGTRNTQNFELLKSVGRQREFPVLLKRGFGITLEESLNAAE
YLASEGNTRVIFGLRGMKTNMGDPHRNFVDFAHVPVVKRLTRMPVCIDPSHSVGSRERAP
DGILDVMHVTAQGVIAGANMILVDFHPNPQKALVDGPQALLLEELPQFLEDVAIARAAYE
QRVALAQRQRAGSAPAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory