Comparing WP_034525928.1 NCBI__GCF_000740055.1:WP_034525928.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8c9hA Aqp7_inhibitor (see paper)
37% identity, 95% coverage: 4:226/235 of query aligns to 12:242/253 of 8c9hA
6n1gA Crystal structure of aquaglyceroporin aqp7 (see paper)
37% identity, 95% coverage: 4:226/235 of query aligns to 6:236/249 of 6n1gA
O14520 Aquaporin-7; AQP-7; Aquaglyceroporin-7; Aquaporin adipose; AQPap; Aquaporin-7-like from Homo sapiens (Human) (see 4 papers)
37% identity, 95% coverage: 4:226/235 of query aligns to 37:267/342 of O14520
Sites not aligning to the query:
P0AER0 Glycerol uptake facilitator protein; Aquaglyceroporin; Glycerol facilitator from Escherichia coli (strain K12) (see 3 papers)
36% identity, 95% coverage: 5:228/235 of query aligns to 12:248/281 of P0AER0
I1CR68 Aquaporin-1 from Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar) (see paper)
34% identity, 95% coverage: 4:226/235 of query aligns to 61:291/306 of I1CR68
1fx8A Crystal structure of the e. Coli glycerol facilitator (glpf) with substrate glycerol (see paper)
36% identity, 95% coverage: 5:228/235 of query aligns to 7:243/254 of 1fx8A
P37451 Propanediol uptake facilitator PduF from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
35% identity, 95% coverage: 7:230/235 of query aligns to 12:248/264 of P37451
B1VB61 Propanediol uptake facilitator PduF from Citrobacter freundii (see paper)
34% identity, 96% coverage: 5:230/235 of query aligns to 10:248/269 of B1VB61
Q96PS8 Aquaporin-10; AQP-10; Aquaglyceroporin-10; Small intestine aquaporin from Homo sapiens (Human) (see 2 papers)
34% identity, 94% coverage: 5:226/235 of query aligns to 25:255/301 of Q96PS8
6f7hC Crystal structure of human aqp10 (see paper)
34% identity, 94% coverage: 5:226/235 of query aligns to 10:240/253 of 6f7hC
3c02A X-ray structure of the aquaglyceroporin from plasmodium falciparum (see paper)
34% identity, 95% coverage: 4:226/235 of query aligns to 6:226/242 of 3c02A
8jy8A Structure of tbaqp2 in complex with anti-trypanosomatid drug pentamidine (see paper)
33% identity, 96% coverage: 2:226/235 of query aligns to 2:231/242 of 8jy8A
8jy6A Structure of tbaqp2 in complex with anti-trypanosomatid drug melarsoprol (see paper)
33% identity, 96% coverage: 2:226/235 of query aligns to 2:231/242 of 8jy6A
2evuA Crystal structure of aquaporin aqpm at 2.3a resolution (see paper)
31% identity, 95% coverage: 5:228/235 of query aligns to 9:237/245 of 2evuA
Q6Z2T3 Aquaporin NIP2-1; Low silicon protein 1; NOD26-like intrinsic protein 2-1; OsNIP2;1; Silicon influx transporter LSI1 from Oryza sativa subsp. japonica (Rice) (see paper)
31% identity, 95% coverage: 1:224/235 of query aligns to 48:251/298 of Q6Z2T3
P08995 Nodulin-26; N-26 from Glycine max (Soybean) (Glycine hispida) (see paper)
30% identity, 95% coverage: 1:224/235 of query aligns to 37:241/271 of P08995
Sites not aligning to the query:
Q9SAI4 Aquaporin NIP6-1; NOD26-like intrinsic protein 6-1; AtNIP6;1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
27% identity, 98% coverage: 6:235/235 of query aligns to 84:289/305 of Q9SAI4
P55088 Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4 from Mus musculus (Mouse) (see 2 papers)
27% identity, 95% coverage: 7:230/235 of query aligns to 41:247/323 of P55088
Sites not aligning to the query:
P47863 Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4 from Rattus norvegicus (Rat) (see 4 papers)
27% identity, 95% coverage: 7:230/235 of query aligns to 41:247/323 of P47863
Sites not aligning to the query:
3nkaA Crystal structure of aqpz h174g,t183f (see paper)
31% identity, 64% coverage: 40:190/235 of query aligns to 41:192/230 of 3nkaA
Sites not aligning to the query:
>WP_034525928.1 NCBI__GCF_000740055.1:WP_034525928.1
MNGFMGEFLGTMILIVLGAGSGAGLNLNKTYAKGQNWLFVSLAWGLAVTMGVYVAGMLGS
DGHLNPAVTIGFAAFGFFPWSQVLPYLLGQFLGAFIGAALVIIQFTPHFKATTNEAEGNS
VGIFATRPAIKAPFFNFLSELITTFVFVFILLNLGNFTEGLKPFIVGMLIAVIGMGLGTT
TGFAINPARDWGPRLAYTILPVPNKGGAEWSYSWVPMVGPLAGGLIAAGLEVLVN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory