SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_034874955.1 NCBI__GCF_001583435.1:WP_034874955.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

1us4A Putative glur0 ligand binding core with l-glutamate (see paper)
31% identity, 91% coverage: 26:302/305 of query aligns to 6:292/297 of 1us4A

query
sites
1us4A
S
 
T
I
 
I
G
 
G
T
 
S
G
 
G
G
 
S
Q
 
T
S
 
T
G
 
G
I
x
V
Y
|
Y
Y
 
F
P
 
P
F
 
V
G
 
A
G
 
T
A
 
G
L
 
I
A
 
A
K
 
K
V
 
L
W
 
V
S
 
N
D
 
D
Q
 
A
I
 
N
D
 
V
G
 
G
V
 
I
N
 
R
V
 
A
K
 
N
A
 
A
E
 
R
V
 
S
T
 
T
A
 
G
A
 
G
S
|
S
V
 
V
E
 
A
N
 
N
T
 
I
I
 
N
K
 
A
V
 
I
V
 
N
R
 
A
G
 
G
D
 
E
M
 
F
I
 
E
A
 
M
G
 
A
L
 
L
A
 
A
M
x
Q
G
 
N
N
 
D
V
 
I
V
 
A
L
 
Y
D
 
Y
A
 
A
Y
 
Y
K
 
Q
G
 
G
-
 
C
-
 
C
-
 
I
-
 
P
-
 
A
-
 
F
E
 
E
G
 
G
K
 
K
F
 
-
P
 
P
A
 
V
K
 
K
M
 
T
P
 
-
V
 
I
N
 
R
V
 
A
L
 
L
F
 
A
A
 
A
L
 
L
Y
 
Y
P
 
P
N
x
E
L
 
V
V
 
V
H
 
H
A
 
V
V
 
V
T
 
A
T
 
R
A
 
K
K
 
D
S
 
A
D
 
G
I
 
I
K
 
R
S
 
T
L
 
V
A
 
A
D
 
D
L
 
L
N
 
K
G
 
G
Q
 
K
R
 
R
V
 
V
S
 
V
L
 
V
G
 
G
A
 
D
P
 
V
G
 
G
S
|
S
G
|
G
T
|
T
A
 
E
V
 
Q
T
 
N
S
 
A
A
 
R
A
 
Q
L
 
I
L
 
L
E
 
E
S
 
A
L
 
Y
G
 
G
V
 
L
D
 
T
V
 
F
N
 
D
-
 
D
-
 
L
-
 
G
-
 
Q
A
 
A
V
 
I
Y
 
R
L
 
V
N
 
S
F
 
A
S
 
S
E
 
Q
T
 
G
T
 
I
N
 
Q
A
 
L
L
 
M
A
 
Q
N
 
D
G
 
K
Q
 
R
I
 
A
D
 
D
A
 
A
G
 
L
F
 
F
I
 
Y
V
x
T
G
x
V
G
 
G
Q
 
L
G
 
G
V
 
A
G
 
S
A
 
A
V
 
I
T
 
Q
Q
 
Q
L
 
L
A
 
A
L
 
L
T
 
T
H
 
T
D
 
P
I
 
I
R
 
A
I
 
L
L
 
V
D
 
A
V
 
V
S
 
D
A
 
L
Q
 
N
Q
 
R
Q
 
I
A
 
Q
T
 
A
F
 
I
K
 
A
S
 
K
K
 
K
Y
 
Y
P
 
P
A
 
F
Y
 
Y
S
 
V
S
 
G
Y
 
F
T
 
N
I
 
I
P
 
P
E
 
G
G
 
G
I
 
T
Y
 
Y
N
 
K
K
 
G
V
 
V
G
 
D
-
 
V
S
 
T
V
 
T
D
 
P
T
 
T
L
 
V
S
 
A
V
 
V
W
 
Q
N
 
A
V
 
M
I
 
L
V
 
I
V
 
A
K
 
S
A
 
E
D
 
R
L
 
L
S
 
S
E
 
E
D
 
E
M
 
T
A
 
V
Y
 
Y
E
 
K
L
 
F
T
 
M
R
 
K
T
 
A
A
 
V
F
 
F
E
 
G
N
 
N
I
 
L
D
 
E
Q
 
A
V
 
F
R
 
K
K
 
K
V
 
I
V
 
H
K
 
P
A
 
N
A
 
L
D
 
E
A
 
R
T
 
F
T
 
F
-
 
G
L
 
L
A
 
E
N
 
K
A
 
A
D
 
V
S
 
K
L
 
G
N
 
L
G
 
P
V
 
I
P
 
P
L
 
L
H
 
H
P
 
P
G
 
G
A
 
A
L
 
E
K
 
R
Y
 
F
L
 
Y
K
 
K

Sites not aligning to the query:

Query Sequence

>WP_034874955.1 NCBI__GCF_001583435.1:WP_034874955.1
MRKLLLSLAVLILPVLSVSVSADNYSIGTGGQSGIYYPFGGALAKVWSDQIDGVNVKAEV
TAASVENTIKVVRGDMIAGLAMGNVVLDAYKGEGKFPAKMPVNVLFALYPNLVHAVTTAK
SDIKSLADLNGQRVSLGAPGSGTAVTSAALLESLGVDVNAVYLNFSETTNALANGQIDAG
FIVGGQGVGAVTQLALTHDIRILDVSAQQQATFKSKYPAYSSYTIPEGIYNKVGSVDTLS
VWNVIVVKADLSEDMAYELTRTAFENIDQVRKVVKAADATTLANADSLNGVPLHPGALKY
LKTVQ

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory