Comparing WP_035237315.1 NCBI__GCF_000745975.1:WP_035237315.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
P0AFK9 Spermidine/putrescine-binding periplasmic protein; SPBP from Escherichia coli (strain K12) (see 3 papers)
57% identity, 95% coverage: 17:344/347 of query aligns to 18:345/348 of P0AFK9
Sites not aligning to the query:
1poy1 Spermidine/putrescine-binding protein complexed with spermidine (dimer form) (see paper)
58% identity, 91% coverage: 28:344/347 of query aligns to 4:320/323 of 1poy1
7xjnA Structure of vcpotd1 in complex with norspermidine
54% identity, 93% coverage: 26:346/347 of query aligns to 3:322/322 of 7xjnA
4eqbA 1.5 angstrom crystal structure of spermidine/putrescine abc transporter substrate-binding protein potd from streptococcus pneumoniae strain canada mdr_19a in complex with calcium and hepes
39% identity, 92% coverage: 25:342/347 of query aligns to 1:306/323 of 4eqbA
Sites not aligning to the query:
Q9I6J0 Spermidine-binding periplasmic protein SpuE from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
33% identity, 100% coverage: 1:346/347 of query aligns to 1:364/365 of Q9I6J0
Q9I6J1 Putrescine-binding periplasmic protein SpuD from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
35% identity, 93% coverage: 1:322/347 of query aligns to 1:341/367 of Q9I6J1
3ttnA Crystal structures of polyamine receptors spud and spue from pseudomonas aeruginosa (see paper)
36% identity, 85% coverage: 28:322/347 of query aligns to 2:312/335 of 3ttnA
3ttmA Crystal structure of spud in complex with putrescine (see paper)
36% identity, 85% coverage: 28:322/347 of query aligns to 5:316/341 of 3ttmA
7oywA E.Coli's putrescine receptor variant potf/d (4jdf) with mutations e39d f88l s247d in complex with spermidine (see paper)
33% identity, 84% coverage: 28:319/347 of query aligns to 4:313/348 of 7oywA
Sites not aligning to the query:
7oyvA E.Coli's putrescine receptor variant potf/d (4jdf) with mutations e39d f88a s247d in complex with spermidine (see paper)
33% identity, 84% coverage: 28:319/347 of query aligns to 4:313/341 of 7oyvA
Sites not aligning to the query:
7oyxB E.Coli's putrescine receptor variant potf/d (4jdf) with mutations e39d y87s f88y s247d in complex with spermidine (see paper)
33% identity, 84% coverage: 28:319/347 of query aligns to 4:313/347 of 7oyxB
Sites not aligning to the query:
8aszA Potf with mutations s87y and a182d in complex with agmatine
33% identity, 84% coverage: 28:319/347 of query aligns to 6:315/343 of 8aszA
P31133 Putrescine-binding periplasmic protein PotF from Escherichia coli (strain K12) (see 3 papers)
32% identity, 89% coverage: 10:319/347 of query aligns to 12:341/370 of P31133
Sites not aligning to the query:
6ye7A E.Coli's putrescine receptor potf complexed with cadaverine (see paper)
32% identity, 84% coverage: 28:319/347 of query aligns to 4:313/341 of 6ye7A
6ye6A E.Coli's putrescine receptor potf complexed with agmatine (see paper)
32% identity, 84% coverage: 28:319/347 of query aligns to 4:313/341 of 6ye6A
Sites not aligning to the query:
6ye0B E.Coli's putrescine receptor potf complexed with putrescine (see paper)
32% identity, 84% coverage: 28:319/347 of query aligns to 4:313/341 of 6ye0B
Sites not aligning to the query:
1a99A Putrescine receptor (potf) from e. Coli (see paper)
32% identity, 84% coverage: 28:319/347 of query aligns to 4:313/341 of 1a99A
4euoA Structure of atu4243-gaba sensor (see paper)
25% identity, 77% coverage: 43:310/347 of query aligns to 21:279/313 of 4euoA
Sites not aligning to the query:
6hlyA Structure in p212121 form of the pbp agtb in complex with agropinic acid from a.Tumefacien r10 (see paper)
24% identity, 80% coverage: 39:315/347 of query aligns to 21:285/320 of 6hlyA
Sites not aligning to the query:
4r74B Structure of the periplasmic binding protein afua from actinobacillus pleuropneumoniae (exogenous fructose-6-phosphate bound) (see paper)
23% identity, 73% coverage: 27:281/347 of query aligns to 5:258/320 of 4r74B
>WP_035237315.1 NCBI__GCF_000745975.1:WP_035237315.1
MKTRFKPLIILAAVLLLAALQAQAAEKIFIYNWTEYLPESVLEQFTKETGIEVVYTTYDS
NETMYAKLKLIKKDGYDVAVPSTYFVSKMGREGMLMKLDHALLPNMKNLDPELLNKDYDP
DNAYSIPYMWGSTGIAVNTDEIPKEQITSWKDLWKPEFKGKLLLQDDLREVFHMALRIKG
FSGNTTNPKEIEQAYLLLKDLMPNVLLFNSDSPRLPFLAGEVSIGMIWNGEAWMAREENP
AIQYVYPKEGASFWVDSFVIPQGARNPKGAHAFINFMMTPEVAKACVEEYGYPTPVTPAI
ALLDTDISSSRTIFPDAGIIKQGEFQNDVGQAIEIYQKYWEKLRTSN
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory