SitesBLAST
Comparing WP_037155072.1 NCBI__GCF_000359745.1:WP_037155072.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4yo7A Crystal structure of an abc transporter solute binding protein (ipr025997) from bacillus halodurans c-125 (bh2323, target efi- 511484) with bound myo-inositol
43% identity, 93% coverage: 21:308/309 of query aligns to 7:286/287 of 4yo7A
- binding 1,2,3,4,5,6-hexahydroxy-cyclohexane: D17 (= D31), N94 (= N109), R95 (= R110), R147 (= R165), N197 (= N217), D223 (= D244), Q243 (= Q264)
- binding magnesium ion: L214 (≠ M235), V217 (≠ I238)
2ioyA Crystal structure of thermoanaerobacter tengcongensis ribose binding protein (see paper)
35% identity, 92% coverage: 21:303/309 of query aligns to 1:274/274 of 2ioyA
- binding beta-D-ribopyranose: N12 (≠ D32), F14 (= F34), F15 (≠ L35), D88 (≠ N109), R89 (= R110), A136 (= A161), R140 (= R165), F164 (≠ W191), N190 (= N217), D215 (= D244), Q235 (= Q264)
P0AEE5 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Escherichia coli (strain K12) (see 4 papers)
36% identity, 99% coverage: 2:308/309 of query aligns to 4:332/332 of P0AEE5
- D37 (= D32) binding beta-D-glucose
- N114 (= N109) binding beta-D-glucose
- D157 (vs. gap) binding Ca(2+)
- N159 (vs. gap) binding Ca(2+)
- D161 (vs. gap) binding Ca(2+)
- Q163 (≠ K147) binding Ca(2+)
- Q165 (≠ K149) binding Ca(2+)
- H175 (≠ N159) binding beta-D-glucose
- D177 (≠ A161) binding beta-D-glucose
- R181 (= R165) binding beta-D-glucose
- E228 (≠ D211) binding Ca(2+)
- N234 (= N217) binding beta-D-glucose
- D259 (= D244) binding beta-D-glucose
- N279 (≠ Q264) binding beta-D-glucose
Sites not aligning to the query:
8fxuA Thermoanaerobacter thermosaccharolyticum periplasmic glucose-binding protein glucose complex: badan conjugate attached at f17c (see paper)
36% identity, 91% coverage: 23:304/309 of query aligns to 6:308/310 of 8fxuA
- binding beta-D-glucopyranose: D15 (= D32), N90 (= N109), R91 (= R110), D153 (≠ A161), R157 (= R165), W182 (= W191), N209 (= N217), D237 (= D244)
- binding calcium ion: D133 (≠ C141), N135 (≠ I143), D137 (≠ G145), V139 (≠ K147), Q141 (≠ K149), E203 (≠ D211)
- binding 2-bromo-1-[6-(dimethylamino)naphthalen-2-yl]ethan-1-one: C17 (≠ F34), D237 (= D244), A238 (= A245), T239 (= T246), N257 (≠ Q264)
P23905 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
34% identity, 99% coverage: 2:308/309 of query aligns to 4:332/332 of P23905
- D37 (= D32) binding beta-D-galactose
- N114 (= N109) binding beta-D-galactose
- D157 (vs. gap) binding Ca(2+)
- N159 (vs. gap) binding Ca(2+)
- D161 (≠ G145) binding Ca(2+)
- K163 (= K147) binding Ca(2+)
- Q165 (≠ K149) binding Ca(2+)
- H175 (≠ N159) binding beta-D-galactose
- D177 (≠ A161) binding beta-D-galactose
- R181 (= R165) binding beta-D-galactose
- E228 (≠ D211) binding Ca(2+)
- N234 (= N217) binding beta-D-galactose
- D259 (= D244) binding beta-D-galactose
- N279 (≠ Q264) binding beta-D-galactose
2gbpA Sugar and signal-transducer binding sites of the escherichia coli galactose chemoreceptor protein (see paper)
36% identity, 93% coverage: 23:308/309 of query aligns to 5:309/309 of 2gbpA
- binding beta-D-glucopyranose: D14 (= D32), N91 (= N109), K92 (≠ R110), H152 (≠ N159), D154 (≠ A161), R158 (= R165), W183 (= W191), N211 (= N217), D236 (= D244), N256 (≠ Q264)
- binding calcium ion: D134 (vs. gap), N136 (vs. gap), D138 (vs. gap), Q140 (≠ K147), Q142 (≠ K149), E205 (≠ D211)
5kwsA Crystal structure of galactose binding protein from yersinia pestis in the complex with beta d glucose
35% identity, 92% coverage: 23:305/309 of query aligns to 5:306/307 of 5kwsA
- binding beta-D-glucopyranose: D14 (= D32), N91 (= N109), K92 (≠ R110), H152 (≠ N159), D154 (≠ A161), R158 (= R165), W183 (= W191), N211 (= N217), D236 (= D244), N256 (≠ Q264)
- binding calcium ion: D134 (vs. gap), N136 (vs. gap), D138 (≠ G145), K140 (= K147), Q142 (≠ K149), E205 (≠ D211)
7e7mC Crystal structure analysis of the streptococcus agalactiae ribose binding protein rbsb
31% identity, 92% coverage: 23:305/309 of query aligns to 11:282/284 of 7e7mC
2qw1A Glucose/galactose binding protein bound to 3-o-methyl d-glucose (see paper)
36% identity, 92% coverage: 23:305/309 of query aligns to 4:305/305 of 2qw1A
1gcaA The 1.7 angstroms refined x-ray structure of the periplasmic glucose(slash)galactose receptor from salmonella typhimurium (see paper)
34% identity, 93% coverage: 23:308/309 of query aligns to 5:309/309 of 1gcaA
- binding calcium ion: D134 (vs. gap), N136 (vs. gap), D138 (≠ G145), K140 (= K147), Q142 (≠ K149), E205 (≠ D211)
- binding beta-D-galactopyranose: D14 (= D32), F16 (= F34), N91 (= N109), K92 (≠ R110), H152 (≠ N159), D154 (≠ A161), R158 (= R165), N211 (= N217), D236 (= D244), N256 (≠ Q264)
A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
35% identity, 97% coverage: 4:302/309 of query aligns to 8:307/349 of A0QYB5
- Y42 (≠ F30) binding D-threitol
- N121 (= N109) binding D-threitol
- R173 (= R165) binding D-threitol
- N224 (= N217) binding D-threitol
- D249 (= D244) binding D-threitol
- Q269 (= Q264) binding D-threitol
3ga5A X-ray structure of glucose/galactose receptor from salmonella typhimurium in complex with (2r)-glyceryl-beta-d-galactopyranoside (see paper)
34% identity, 92% coverage: 23:305/309 of query aligns to 3:304/305 of 3ga5A
- binding calcium ion: D132 (vs. gap), N134 (vs. gap), D136 (≠ G145), K138 (= K147), Q140 (≠ K149), E203 (≠ D211)
- binding (2R)-2,3-dihydroxypropyl beta-D-galactopyranoside: D12 (= D32), F14 (= F34), N89 (= N109), K90 (≠ R110), T108 (≠ S127), H150 (≠ N159), D152 (≠ A161), R156 (= R165), W181 (= W191), N209 (= N217), D234 (= D244), N254 (≠ Q264), Q259 (= Q269)
8fxtA Escherichia coli periplasmic glucose-binding protein glucose complex: acrylodan conjugate attached at w183c (see paper)
35% identity, 93% coverage: 20:305/309 of query aligns to 1:305/305 of 8fxtA
- binding beta-D-glucopyranose: D12 (= D31), D12 (= D31), D13 (= D32), N14 (= N33), D39 (= D58), Q41 (= Q60), N90 (= N109), D120 (≠ K138), K124 (≠ R142), H151 (≠ N159), D153 (≠ A161), R157 (= R165), D183 (≠ Q192), T184 (≠ R193), K188 (≠ A197), D189 (= D198), N210 (= N217), D235 (= D244), N255 (≠ Q264), G296 (≠ L296), D298 (≠ T298), N301 (= N301)
- binding calcium ion: D133 (vs. gap), N135 (vs. gap), D137 (vs. gap), Q139 (≠ K147), Q141 (≠ K149), E204 (≠ D211)
- binding alpha-D-glucopyranose: D13 (= D32), N90 (= N109), H151 (≠ N159), D153 (≠ A161), R157 (= R165), N210 (= N217), D235 (= D244), N255 (≠ Q264)
- binding 1-[6-(dimethylamino)naphthalen-2-yl]propan-1-one: Y9 (≠ A28), N42 (= N61), E148 (= E156), M181 (≠ N190), C182 (≠ W191)
4z0nA Crystal structure of a periplasmic solute binding protein (ipr025997) from streptobacillus moniliformis dsm-12112 (smon_0317, target efi- 511281) with bound d-galactose
34% identity, 93% coverage: 22:307/309 of query aligns to 3:307/307 of 4z0nA
- active site: T7 (≠ S26), Q45 (≠ V63), S46 (≠ A64), L89 (≠ Y107), V96 (= V115), Y107 (≠ F124), G109 (≠ A126), M192 (= M200), S221 (≠ A227)
- binding calcium ion: D134 (vs. gap), N136 (≠ G145), D138 (≠ K147), V140 (vs. gap), Q142 (≠ K149), E205 (≠ D211)
- binding beta-D-galactopyranose: D13 (= D32), F15 (= F34), N91 (= N109), K92 (≠ R110), Q152 (≠ N159), D154 (≠ A161), R158 (= R165), W183 (= W191), N211 (= N217), D235 (= D244), Q255 (= Q264)
A0QYB3 Xylitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
34% identity, 93% coverage: 16:302/309 of query aligns to 28:307/349 of A0QYB3