Comparing WP_037573048.1 NCBI__GCF_000744815.1:WP_037573048.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q9K4B1 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
75% identity, 100% coverage: 1:263/264 of query aligns to 1:263/266 of Q9K4B1
P95189 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
60% identity, 98% coverage: 5:264/264 of query aligns to 3:259/260 of P95189
5zonA Histidinol phosphate phosphatase from mycobacterium tuberculosis (see paper)
60% identity, 98% coverage: 5:263/264 of query aligns to 1:256/256 of 5zonA
5yhtA Crystal structure of a phosphatase from mycobacterium tuberculosis in complex with its substrate (see paper)
60% identity, 98% coverage: 6:263/264 of query aligns to 1:255/255 of 5yhtA
Q6NPM8 Bifunctional phosphatase IMPL2, chloroplastic; Histidinol-phosphatase; Histidinol-phosphate phosphatase; HPP; Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Protein HISTIDINE BIOSYNTHESIS 7; Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 2; EC 3.1.3.15; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 87% coverage: 10:239/264 of query aligns to 89:310/346 of Q6NPM8
2p3nA Thermotoga maritima impase tm1415 (see paper)
32% identity, 85% coverage: 33:256/264 of query aligns to 28:240/256 of 2p3nA
O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
32% identity, 85% coverage: 33:256/264 of query aligns to 28:240/256 of O33832
5eq9B Crystal structure of medicago truncatula histidinol-phosphate phosphatase (mthpp) in complex with l-histidinol phosphate and mg2+ (see paper)
32% identity, 77% coverage: 38:239/264 of query aligns to 31:225/260 of 5eq9B
5eq8A Crystal structure of medicago truncatula histidinol-phosphate phosphatase (mthpp) in complex with l-histidinol (see paper)
32% identity, 77% coverage: 38:239/264 of query aligns to 30:224/259 of 5eq8A
5t3jA Histidinol phosphate phosphatase(hpp) soaked with selenourea for 10 min (see paper)
32% identity, 76% coverage: 40:239/264 of query aligns to 30:222/257 of 5t3jA
Sites not aligning to the query:
8wdqA Crystal structure of pseudomonas aeruginosa suhb in complex with d- myo-inositol-1-phosphate
33% identity, 92% coverage: 22:263/264 of query aligns to 24:264/273 of 8wdqA
4as5A Structure of mouse inositol monophosphatase 1 (see paper)
31% identity, 89% coverage: 5:240/264 of query aligns to 4:240/274 of 4as5A
3luzB Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
32% identity, 80% coverage: 42:251/264 of query aligns to 28:221/234 of 3luzB
Sites not aligning to the query:
Q19420 Inositol monophosphatase ttx-7; IMP; IMPase; Abnormal thermotaxis protein 7; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase; EC 3.1.3.25; EC 3.1.3.94 from Caenorhabditis elegans (see paper)
30% identity, 86% coverage: 14:240/264 of query aligns to 20:252/285 of Q19420
3luzA Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
31% identity, 80% coverage: 42:251/264 of query aligns to 27:225/238 of 3luzA
Sites not aligning to the query:
3lv0A Crystal structure of extragenic suppressor protein suhb from bartonella henselae, native
31% identity, 84% coverage: 30:251/264 of query aligns to 27:243/258 of 3lv0A
Q9M8S8 Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Myo-inositol monophosphatase; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
33% identity, 85% coverage: 32:256/264 of query aligns to 34:260/271 of Q9M8S8
O55023 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Mus musculus (Mouse) (see paper)
31% identity, 89% coverage: 5:240/264 of query aligns to 6:242/277 of O55023
1imdA Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis (see paper)
30% identity, 89% coverage: 5:240/264 of query aligns to 2:238/266 of 1imdA
2bjiA High resolution structure of myo-inositol monophosphatase, the target of lithium therapy (see paper)
30% identity, 89% coverage: 5:240/264 of query aligns to 4:240/274 of 2bjiA
>WP_037573048.1 NCBI__GCF_000744815.1:WP_037573048.1
MPDFHDDLRLAHVLADHADSVTTERFKALDLRVETKPDLTPVSDADKAAEDVVRSVLSRA
RPRDAVMGEEHGVTGHGPRRWVIDPIDGTKNYVRGVPVWATLISLLELGPGGEEPVVGLV
SAPALGKRWWSAKGSGAFTGRSLARATRLQVSDVSRLSDASLSYSSLTGWEERGLLPNFV
DLSRKVWRTRAFGDFWSYMMVAEGAVDLAAEPELSLWDMAAPCAIVTEAGGRFTDLQGRP
GVHGPNAVASNGLLHEALLGSLNA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory