SitesBLAST
Comparing WP_037575401.1 NCBI__GCF_000744815.1:WP_037575401.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
7omlA Bacillus subtilis phosphoglucomutase glmm (metal bound) (see paper)
47% identity, 99% coverage: 2:454/456 of query aligns to 1:444/445 of 7omlA
7ojrA Bacillus subtilis phosphoglucomutase glmm (phosphate bound) (see paper)
47% identity, 99% coverage: 2:454/456 of query aligns to 1:444/445 of 7ojrA
P31120 Phosphoglucosamine mutase; EC 5.4.2.10 from Escherichia coli (strain K12) (see 3 papers)
44% identity, 98% coverage: 3:451/456 of query aligns to 5:443/445 of P31120
- S100 (= S102) mutation to A: 2% of wild-type activity.; mutation to T: 20-fold increase in the non-specific phosphoglucomutase activity towards glucose-phosphate substrates (non aminated).
- S102 (= S104) active site, Phosphoserine intermediate; modified: Phosphoserine; by autocatalysis; mutation to A: Loss of activity in the absence or presence of glucosamine-1,6-diP.
Sites not aligning to the query:
- 1 modified: Initiator methionine, Removed
3i3wA Structure of a phosphoglucosamine mutase from francisella tularensis
39% identity, 99% coverage: 3:454/456 of query aligns to 1:440/441 of 3i3wA
- active site: R9 (= R11), S99 (= S104), H100 (= H105), K109 (= K114), D237 (= D249), D239 (= D251), D241 (= D253), R242 (= R254), H324 (= H338)
- binding zinc ion: S99 (= S104), D237 (= D249), D239 (= D251), D241 (= D253)
1wqaA Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
34% identity, 96% coverage: 1:440/456 of query aligns to 1:440/455 of 1wqaA
- active site: R11 (= R11), S101 (= S104), H102 (= H105), K111 (= K114), D243 (= D249), D245 (= D251), D247 (= D253), R248 (= R254), G330 (≠ H338), R340 (≠ G348)
- binding magnesium ion: S101 (= S104), D243 (= D249), D245 (= D251), D247 (= D253)
6mlwA Crystal structure of x. Citri phosphoglucomutase in complex with 2- fluoro mannosyl-1-methyl-phosphonic acid (see paper)
30% identity, 98% coverage: 5:451/456 of query aligns to 7:448/449 of 6mlwA
- active site: R13 (= R11), S98 (= S104), H99 (= H105), K108 (= K114), D238 (= D249), D240 (= D251), D242 (= D253), R243 (= R254), H325 (= H338)
- binding 2,6-anhydro-5,7-dideoxy-5-fluoro-7-phosphono-D-glycero-D-manno-heptitol: G303 (= G316), H304 (≠ D317), E321 (= E334), S323 (= S336), H325 (= H338), R415 (= R419), S417 (= S421), N418 (≠ G422), T419 (= T423), R424 (= R428)
- binding magnesium ion: S98 (= S104), D238 (= D249), D240 (= D251), D242 (= D253)
5bmpA Crystal structure of phosphoglucomutase from xanthomonas citri complexed with glucose-1-phosphate (see paper)
30% identity, 98% coverage: 5:451/456 of query aligns to 7:448/449 of 5bmpA
- active site: R13 (= R11), S98 (= S104), H99 (= H105), K108 (= K114), D238 (= D249), D240 (= D251), D242 (= D253), R243 (= R254), H325 (= H338)
- binding 1-O-phosphono-alpha-D-glucopyranose: R281 (vs. gap), G303 (= G316), E321 (= E334), S323 (= S336), H325 (= H338), R415 (= R419), S417 (= S421), N418 (≠ G422), T419 (= T423), R424 (= R428)
- binding magnesium ion: S98 (= S104), D238 (= D249), D240 (= D251), D242 (= D253)
6nqhA Xanthomonas citri dephospho-pgm in complex with xylose-1-phosphate
30% identity, 98% coverage: 5:451/456 of query aligns to 6:447/448 of 6nqhA
- active site: R12 (= R11), S97 (= S104), H98 (= H105), K107 (= K114), D237 (= D249), D239 (= D251), D241 (= D253), R242 (= R254), H324 (= H338)
- binding magnesium ion: D237 (= D249), D239 (= D251), D241 (= D253)
- binding 1-O-phosphono-alpha-D-xylopyranose: R12 (= R11), S97 (= S104), H98 (= H105), K107 (= K114), D239 (= D251), R242 (= R254), R280 (vs. gap), S301 (≠ A314), G302 (= G316), E320 (= E334), S322 (= S336), H324 (= H338), R414 (= R419), S416 (= S421), N417 (≠ G422), T418 (= T423), R423 (= R428)
6np8A Xanthomonas citri phospho-pgm in complex with mannose-6-phosphate (see paper)
30% identity, 98% coverage: 5:451/456 of query aligns to 6:447/448 of 6np8A
- active site: R12 (= R11), S97 (= S104), H98 (= H105), K107 (= K114), D237 (= D249), D239 (= D251), D241 (= D253), R242 (= R254), H324 (= H338)
- binding calcium ion: S97 (= S104), D237 (= D249), D239 (= D251), D241 (= D253)
- binding 6-O-phosphono-alpha-D-mannopyranose: Y9 (≠ D8), R280 (vs. gap), G302 (= G316), H303 (≠ D317), E320 (= E334), S322 (= S336), H324 (= H338), R414 (= R419), S416 (= S421), N417 (≠ G422), T418 (= T423), R423 (= R428)
6nolA Xanthomonas citri dephospho-pgm in complex with mannose-1-phosphate (see paper)
30% identity, 98% coverage: 5:451/456 of query aligns to 6:447/448 of 6nolA