SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_037577568.1 NCBI__GCF_000744815.1:WP_037577568.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 5 hits to proteins with known functional sites (download)

7bywA Crystal structure of acidovorax avenae l-fucose mutarotase (l-fucose- bound form) (see paper)
49% identity, 99% coverage: 2:107/107 of query aligns to 1:108/108 of 7bywA

query
sites
7bywA
E
 
Q
R
 
R
H
 
M
A
 
G
Q
 
M
I
 
V
V
 
I
R
 
G
L
 
I
R
 
K
P
 
P
E
 
E
H
 
H
E
 
I
A
 
D
E
 
E
Y
|
Y
R
 
K
R
 
R
I
 
L
H
|
H
Q
 
A
Q
 
A
V
 
V
W
 
W
P
 
P
A
 
A
V
 
V
L
 
L
R
 
A
T
 
R
I
 
L
H
 
A
A
 
E
C
 
A
N
 
H
I
 
V
R
 
R
N
 
N
Y
|
Y
S
 
S
I
 
I
F
 
F
L
 
L
N
 
R
D
 
E
-
 
P
-
 
E
G
 
N
V
 
L
L
 
L
F
 
F
A
 
G
Y
 
Y
Y
 
W
E
 
E
Y
 
Y
V
 
H
G
 
G
E
 
T
D
 
D
H
 
Y
A
 
A
A
 
A
D
 
D
M
 
M
A
 
E
K
 
A
M
 
I
A
 
A
E
 
Q
D
 
D
P
 
P
E
 
E
T
 
T
Q
 
R
R
 
R
W
|
W
W
|
W
K
 
T
I
 
F
T
 
C
D
 
G
P
 
P
M
 
C
Q
 
Q
S
 
E
P
 
P
L
 
L
D
 
A
G
 
S
T
 
R
P
 
Q
E
 
P
G
 
G
Q
 
E
W
 
H
W
 
W
A
 
A
P
 
H
A
 
M
E
 
E
E
 
E
V
 
V
F
 
F
H
 
H
T
 
V
D
 
D

2qlxA Crystal structure of rhamnose mutarotase rhau of rhizobium leguminosarum in complex with l-rhamnose (see paper)
33% identity, 86% coverage: 1:92/107 of query aligns to 5:96/108 of 2qlxA

query
sites
2qlxA
M
 
L
E
 
E
R
 
K
H
 
H
A
 
A
Q
 
F
I
 
K
V
x
M
R
 
Q
L
 
L
R
 
N
P
 
P
E
 
G
H
 
M
E
 
E
A
 
A
E
 
E
Y
|
Y
R
 
R
R
 
K
I
 
R
H
|
H
Q
 
D
Q
 
E
V
 
I
W
 
W
P
 
P
A
 
E
V
 
L
L
 
V
R
 
D
T
 
L
I
 
L
H
 
H
A
 
Q
C
 
S
N
 
G
I
 
A
R
 
S
N
 
D
Y
|
Y
S
 
S
I
 
I
F
 
H
L
 
L
N
 
D
-
 
R
-
 
E
D
 
T
G
 
N
V
 
T
L
 
L
F
 
F
A
 
G
Y
 
V
Y
 
L
E
 
T
Y
 
R
V
 
-
G
 
P
E
 
K
D
 
D
H
 
H
A
 
T
A
 
-
D
 
-
M
 
M
A
 
A
K
 
S
M
 
L
A
 
P
E
 
D
D
 
H
P
 
P
E
 
V
T
 
M
Q
 
K
R
 
K
W
|
W
W
|
W
K
 
A
-
 
H
I
 
M
T
 
A
D
 
D
P
 
I
M
 
M
Q
 
A
S
 
T
P
 
N
L
 
P
D
 
D
G
 
N
T
 
S
P
 
P

2qlwB Crystal structure of rhamnose mutarotase rhau of rhizobium leguminosarum (see paper)
33% identity, 86% coverage: 1:92/107 of query aligns to 5:96/108 of 2qlwB

query
sites
2qlwB
M
 
L
E
 
E
R
 
K
H
 
H
A
 
A
Q
 
F
I
 
K
V
 
M
R
 
Q
L
 
L
R
 
N
P
 
P
E
 
G
H
 
M
E
 
E
A
 
A
E
 
E
Y
 
Y
R
 
R
R
 
K
I
 
R
H
 
H
Q
 
D
Q
 
E
V
 
I
W
 
W
P
 
P
A
 
E
V
 
L
L
 
V
R
 
D
T
 
L
I
 
L
H
 
H
A
 
Q
C
 
S
N
 
G
I
 
A
R
 
S
N
 
D
Y
 
Y
S
 
S
I
 
I
F
 
H
L
 
L
N
 
D
-
 
R
-
 
E
D
 
T
G
 
N
V
 
T
L
 
L
F
 
F
A
 
G
Y
 
V
Y
 
L
E
 
T
Y
 
R
V
 
-
G
 
P
E
 
K
D
 
D
H
 
H
A
 
T
A
 
-
D
 
-
M
 
M
A
 
A
K
 
S
M
 
L
A
 
P
E
 
D
D
 
H
P
 
P
E
 
V
T
 
M
Q
 
K
R
 
K
W
 
W
W
 
W
K
 
A
-
 
H
I
 
M
T
x
A
D
 
D
P
 
I
M
|
M
Q
 
A
S
x
T
P
 
N
L
 
P
D
 
D
G
 
N
T
 
S
P
 
P

1x8dA Crystal structure of e. Coli yiil protein containing l-rhamnose (see paper)
31% identity, 98% coverage: 1:105/107 of query aligns to 1:102/104 of 1x8dA

query
sites
1x8dA
M
 
M
E
 
I
R
 
R
H
 
K
A
 
A
Q
 
F
I
 
V
V
 
M
R
 
Q
L
 
V
R
 
N
P
 
P
E
 
D
H
 
A
E
 
H
A
 
E
E
 
E
Y
|
Y
R
 
Q
R
 
R
I
 
R
H
|
H
Q
 
N
Q
 
P
V
 
I
W
 
W
P
 
P
A
 
E
V
 
L
L
 
E
R
 
A
T
 
V
I
 
L
H
 
K
A
 
S
C
 
H
N
 
G
I
 
A
R
 
H
N
 
N
Y
|
Y
S
 
A
I
 
I
F
 
Y
L
 
L
N
 
D
D
 
K
G
 
A
-
 
R
-
 
N
V
 
L
L
 
L
F
 
F
A
 
A
Y
 
M
Y
 
V
E
 
E
Y
 
I
V
 
E
G
 
S
E
 
E
D
 
E
H
 
R
A
 
-
A
 
-
D
 
-
M
 
W
A
 
N
K
 
A
M
 
V
A
 
A
E
 
S
D
 
T
P
 
D
E
 
V
T
 
C
Q
 
Q
R
 
R
W
|
W
W
|
W
K
 
K
-
 
Y
I
 
M
T
 
T
D
 
D
P
 
V
M
 
M
Q
 
P
S
 
A
P
 
N
L
 
P
D
 
D
G
 
N
T
 
S
P
 
P
E
 
V
G
 
S
Q
 
-
W
 
-
W
 
-
A
 
S
P
 
E
A
 
L
E
 
Q
E
 
E
V
 
V
F
 
F
H
 
Y

P32156 L-rhamnose mutarotase; Rhamnose 1-epimerase; Type-3 mutarotase; EC 5.1.3.32 from Escherichia coli (strain K12) (see paper)
31% identity, 98% coverage: 1:105/107 of query aligns to 1:102/104 of P32156

query
sites
P32156
M
 
M
E
 
I
R
 
R
H
 
K
A
 
A
Q
 
F
I
 
V
V
 
M
R
 
Q
L
 
V
R
 
N
P
 
P
E
 
D
H
 
A
E
 
H
A
 
E
E
 
E
Y
|
Y
R
 
Q
R
 
R
I
 
R
H
 
H
Q
 
N
Q
 
P
V
 
I
W
 
W
P
 
P
A
 
E
V
 
L
L
 
E
R
 
A
T
 
V
I
 
L
H
 
K
A
 
S
C
 
H
N
 
G
I
 
A
R
 
H
N
 
N
Y
 
Y
S
 
A
I
 
I
F
 
Y
L
 
L
N
 
D
D
 
K
G
 
A
-
 
R
-
 
N
V
 
L
L
 
L
F
 
F
A
 
A
Y
 
M
Y
 
V
E
 
E
Y
 
I
V
 
E
G
 
S
E
 
E
D
 
E
H
 
R
A
 
-
A
 
-
D
 
-
M
 
W
A
 
N
K
 
A
M
 
V
A
 
A
E
 
S
D
 
T
P
 
D
E
 
V
T
 
C
Q
 
Q
R
 
R
W
 
W
W
 
W
K
 
K
-
 
Y
I
 
M
T
 
T
D
 
D
P
 
V
M
 
M
Q
 
P
S
 
A
P
 
N
L
 
P
D
 
D
G
 
N
T
 
S
P
 
P
E
 
V
G
 
S
Q
 
-
W
 
-
W
 
-
A
 
S
P
 
E
A
 
L
E
 
Q
E
 
E
V
 
V
F
 
F
H
 
Y

Query Sequence

>WP_037577568.1 NCBI__GCF_000744815.1:WP_037577568.1
MERHAQIVRLRPEHEAEYRRIHQQVWPAVLRTIHACNIRNYSIFLNDGVLFAYYEYVGED
HAADMAKMAEDPETQRWWKITDPMQSPLDGTPEGQWWAPAEEVFHTD

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory