SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_038018225.1 NCBI__GCF_000757425.2:WP_038018225.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

P46318 Lichenan-specific phosphotransferase enzyme IIB component; EIIB-Lic; PTS system lichenan-specific EIIB component; EC 2.7.1.- from Bacillus subtilis (strain 168) (see paper)
47% identity, 95% coverage: 3:96/99 of query aligns to 2:95/102 of P46318

query
sites
P46318
N
 
N
I
 
I
L
 
L
L
 
L
C
 
V
C
 
C
A
 
A
A
 
A
G
 
G
M
 
M
S
 
S
T
 
T
S
 
S
M
 
L
L
 
L
V
 
V
S
 
S
R
 
K
M
 
M
Q
 
E
K
 
K
Y
 
S
A
 
A
A
 
Q
D
 
E
Q
 
Q
A
 
G
I
 
K
D
 
D
V
 
Y
E
 
T
I
 
I
N
 
W
A
 
A
I
 
V
S
|
S
I
 
G
N
 
D
E
 
S
L
 
V
D
 
Q
S
 
N
H
 
H
L
 
I
A
 
D
N
 
K
I
 
A
D
 
D
C
 
V
C
 
L
L
 
L
L
 
L
G
 
G
P
 
P
Q
 
Q
V
 
V
K
 
R
Y
 
Y
K
 
M
L
 
L
A
 
P
E
 
Q
V
 
L
Q
 
K
Q
 
K
K
 
L
L
 
G
A
 
E
P
 
S
L
 
K
N
 
G
I
 
V
P
 
P
V
 
V
A
 
D
V
 
V
I
 
I
D
 
N
I
 
T
R
 
V
D
 
H
Y
 
Y
G
 
G
M
 
T
M
 
C
R
 
N
G
 
G
D
 
A
K
 
E
V
 
V
L
 
L
E
 
K
S
 
S
A
 
A

2wy2D Nmr structure of the iiachitobiose-iibchitobiose phosphoryl transition state complex of the n,n'-diacetylchitoboise brance of the e. Coli phosphotransferase system. (see paper)
45% identity, 93% coverage: 2:93/99 of query aligns to 2:91/103 of 2wy2D

query
sites
2wy2D
K
 
K
N
 
H
I
 
I
L
 
Y
L
 
L
C
 
F
C
|
C
A
x
S
A
|
A
G
|
G
M
|
M
S
|
S
T
 
T
S
 
S
M
 
L
L
 
L
V
 
V
S
 
S
R
 
K
M
 
M
Q
 
R
K
 
A
Y
 
Q
A
 
A
A
 
E
D
 
K
Q
 
Y
A
 
E
I
 
V
D
 
P
V
 
V
E
 
I
I
 
I
N
 
E
A
 
A
I
 
F
S
 
P
I
 
E
N
 
T
E
 
L
L
 
A
D
 
G
S
 
E
H
 
K
L
 
G
A
 
Q
N
 
N
I
 
A
D
 
D
C
 
V
C
 
V
L
 
L
L
 
L
G
 
G
P
 
P
Q
 
Q
V
 
I
K
 
A
Y
 
Y
K
 
M
L
 
L
A
 
P
E
 
E
V
 
I
Q
 
Q
Q
 
R
K
 
L
L
 
L
A
 
P
P
 
-
L
 
-
N
 
N
I
 
K
P
 
P
V
 
V
A
 
E
V
 
V
I
 
I
D
 
D
I
 
S
R
 
L
D
 
L
Y
 
Y
G
 
G
M
 
K
M
 
V
R
 
D
G
 
G
D
 
L
K
 
G
V
 
V
L
 
L

P69795 PTS system N,N'-diacetylchitobiose-specific EIIB component; EIIB-Chb; IVcel; N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component; EC 2.7.1.196 from Escherichia coli (strain K12) (see 2 papers)
45% identity, 93% coverage: 2:93/99 of query aligns to 4:93/106 of P69795

query
sites
P69795
K
 
K
N
 
H
I
 
I
L
 
Y
L
 
L
C
 
F
C
|
C
A
 
S
A
 
A
G
 
G
M
 
M
S
 
S
T
 
T
S
 
S
M
 
L
L
 
L
V
 
V
S
 
S
R
 
K
M
 
M
Q
 
R
K
 
A
Y
 
Q
A
 
A
A
 
E
D
 
K
Q
 
Y
A
 
E
I
 
V
D
 
P
V
 
V
E
 
I
I
 
I
N
 
E
A
 
A
I
 
F
S
 
P
I
 
E
N
 
T
E
 
L
L
 
A
D
 
G
S
 
E
H
 
K
L
 
G
A
 
Q
N
 
N
I
 
A
D
 
D
C
 
V
C
 
V
L
 
L
L
 
L
G
 
G
P
 
P
Q
 
Q
V
 
I
K
 
A
Y
 
Y
K
 
M
L
 
L
A
 
P
E
 
E
V
 
I
Q
 
Q
Q
 
R
K
 
L
L
 
L
A
 
P
P
 
-
L
 
-
N
 
N
I
 
K
P
 
P
V
 
V
A
 
E
V
 
V
I
 
I
D
 
D
I
 
S
R
 
L
D
 
L
Y
 
Y
G
 
G
M
 
K
M
 
V
R
 
D
G
 
G
D
 
L
K
 
G
V
 
V
L
 
L

Query Sequence

>WP_038018225.1 NCBI__GCF_000757425.2:WP_038018225.1
MKNILLCCAAGMSTSMLVSRMQKYAADQAIDVEINAISINELDSHLANIDCCLLGPQVKY
KLAEVQQKLAPLNIPVAVIDIRDYGMMRGDKVLESALAM

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory