Comparing WP_041099981.1 NCBI__GCF_000828635.1:WP_041099981.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q8K4H1 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Mus musculus (Mouse) (see paper)
34% identity, 97% coverage: 2:275/282 of query aligns to 16:298/305 of Q8K4H1
4po3X Crystal structure of a c4-c4 sn3 tributyrin phosphonate inhibited by esterase b from lactobacillus rhamnosis
34% identity, 44% coverage: 29:153/282 of query aligns to 26:154/309 of 4po3X
Sites not aligning to the query:
4n5iX Crystal structure of a c8-c4 sn3 inhibited esterase b from lactobacillus rhamnosis
34% identity, 44% coverage: 29:153/282 of query aligns to 23:151/311 of 4n5iX
Sites not aligning to the query:
4oukX Crystal structure of a c6-c4 sn3 inhibited esterase b from lactobacillus rhamnosis
34% identity, 44% coverage: 29:153/282 of query aligns to 23:151/309 of 4oukX
Sites not aligning to the query:
5hc0A Structure of esterase est22 with p-nitrophenol (see paper)
29% identity, 43% coverage: 30:149/282 of query aligns to 38:187/338 of 5hc0A
Sites not aligning to the query:
6ieyA Crystal structure of chloramphenicol-metabolizaing enzyme estdl136- chloramphenicol complex (see paper)
35% identity, 30% coverage: 66:151/282 of query aligns to 67:153/307 of 6ieyA
Sites not aligning to the query:
5aobA The structure of a novel thermophilic esterase from the planctomycetes species, thermogutta terrifontis, est2-butyrate bound (see paper)
31% identity, 35% coverage: 55:154/282 of query aligns to 33:132/278 of 5aobA
5aocA The structure of a novel thermophilic esterase from the planctomycetes species, thermogutta terrifontis, est2-valerate bound (see paper)
31% identity, 35% coverage: 55:154/282 of query aligns to 37:136/277 of 5aocA
Sites not aligning to the query:
5hc2A Structure of esterase est22 mutant-s188a with p-nitrophenol (see paper)
29% identity, 43% coverage: 30:149/282 of query aligns to 43:192/343 of 5hc2A
Sites not aligning to the query:
7bfrA Thermogutta terrifontis esterase 2 phosphorylated by paraoxon (see paper)
31% identity, 35% coverage: 55:154/282 of query aligns to 33:132/260 of 7bfrA
Sites not aligning to the query:
1qz3A Crystal structure of mutant m211s/r215l of carboxylesterase est2 complexed with hexadecanesulfonate (see paper)
33% identity, 31% coverage: 65:152/282 of query aligns to 74:162/309 of 1qz3A
Sites not aligning to the query:
4ob6A Complex structure of esterase rppe s159a/w187h and substrate (s)-ac- cpa (see paper)
29% identity, 32% coverage: 65:153/282 of query aligns to 80:169/319 of 4ob6A
Sites not aligning to the query:
7auyA Structure of estd11 in complex with fluorescein (see paper)
33% identity, 43% coverage: 66:187/282 of query aligns to 68:182/277 of 7auyA
Sites not aligning to the query:
P15304 Hormone-sensitive lipase; HSL; Monoacylglycerol lipase LIPE; Retinyl ester hydrolase; REH; EC 3.1.1.79; EC 3.1.1.23 from Rattus norvegicus (Rat) (see 2 papers)
32% identity, 32% coverage: 60:150/282 of query aligns to 638:729/1068 of P15304
Sites not aligning to the query:
P24484 Lipase 2; Triacylglycerol lipase; EC 3.1.1.3 from Moraxella sp. (strain TA144) (see paper)
33% identity, 31% coverage: 67:153/282 of query aligns to 161:248/433 of P24484
Q7M370 Arylacetamide deacetylase; 50 kDa microsomal esterase/N-deacetylase; EC 3.1.1.3 from Oryctolagus cuniculus (Rabbit) (see 3 papers)
33% identity, 30% coverage: 67:151/282 of query aligns to 106:195/398 of Q7M370
Sites not aligning to the query:
7w1jA Crystal structure of carboxylesterase from thermobifida fusca with j1k
29% identity, 32% coverage: 65:155/282 of query aligns to 98:195/494 of 7w1jA
Sites not aligning to the query:
7w1iA Crystal structure of carboxylesterase mutant from thermobifida fusca with c8x and c9c
29% identity, 32% coverage: 65:155/282 of query aligns to 99:196/497 of 7w1iA
Sites not aligning to the query:
7atqA Structure of estd11 in complex with cyclohexane carboxylic acid (see paper)
32% identity, 42% coverage: 66:183/282 of query aligns to 68:177/295 of 7atqA
Sites not aligning to the query:
7atfA Structure of estd11 in complex with p-nitrophenol (see paper)
32% identity, 42% coverage: 66:183/282 of query aligns to 68:177/295 of 7atfA
Sites not aligning to the query:
>WP_041099981.1 NCBI__GCF_000828635.1:WP_041099981.1
MLTPEQLDREYNARAAIPEHPRIFERWRAESRAARDQLRCETDYHFGPSPAESLDLYPAA
ARNAPLLVFIHGGYWRSLDKQDFSFLAPAFVRAGVAVAMPNYDLAPAASIESMVQQMLRA
MAWLYRTVPQLGIDAQRIVVAGHSAGAHLAAMMLAADWPAWARDLPPDLLSGAVCISGIY
DLQPLVRAPFLRADLKLDDETAQRVSPVRYQPGLATPLITAVGGDESGEFRRQNRLIRQA
WPQCFHRDLPLPGRHHLASVEALGEPDHPLFQATLHLLGKTP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory