Comparing WP_042119339.1 NCBI__GCF_000092045.1:WP_042119339.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5gupE structure of mammalian respiratory supercomplex I1III2IV1 (see paper)
45% identity, 84% coverage: 5:151/174 of query aligns to 39:187/197 of 5gupE
7dgq9 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (see paper)
45% identity, 84% coverage: 5:151/174 of query aligns to 22:170/207 of 7dgq9
Sites not aligning to the query:
7v2cO Active state complex i from q10 dataset (see paper)
45% identity, 84% coverage: 5:151/174 of query aligns to 29:177/217 of 7v2cO
P04394 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH dehydrogenase subunit II; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Bos taurus (Bovine) (see 2 papers)
45% identity, 84% coverage: 5:151/174 of query aligns to 61:209/249 of P04394
Sites not aligning to the query:
Q9D6J6 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Mus musculus (Mouse) (see paper)
46% identity, 84% coverage: 5:151/174 of query aligns to 60:208/248 of Q9D6J6
P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NDUFV2; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Homo sapiens (Human) (see 2 papers)
44% identity, 84% coverage: 5:151/174 of query aligns to 61:209/249 of P19404
Sites not aligning to the query:
7zmbH Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 2) (see paper)
43% identity, 94% coverage: 7:169/174 of query aligns to 29:190/221 of 7zmbH
7b0nE 3.7-angstrom structure of Yarrowia lipolytica complex I with an R121M mutation in NUCM. (see paper)
41% identity, 98% coverage: 5:174/174 of query aligns to 26:187/216 of 7b0nE
8eswV2 NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A (see paper)
41% identity, 90% coverage: 4:159/174 of query aligns to 25:182/214 of 8eswV2
8b9zE Drosophila melanogaster complex i in the active state (dm1) (see paper)
41% identity, 90% coverage: 4:159/174 of query aligns to 25:182/214 of 8b9zE
3iam2 Crystal structure of the hydrophilic domain of respiratory complex i from thermus thermophilus, reduced, 2 mol/asu, with bound nadh (see paper)
44% identity, 86% coverage: 7:155/174 of query aligns to 10:161/179 of 3iam2
Q56221 NADH-quinone oxidoreductase subunit 2; NADH dehydrogenase I chain 2; NDH-1 subunit 2; EC 7.1.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
44% identity, 86% coverage: 7:155/174 of query aligns to 11:162/181 of Q56221
Sites not aligning to the query:
3i9v2 Crystal structure of the hydrophilic domain of respiratory complex i from thermus thermophilus, oxidized, 2 mol/asu (see paper)
44% identity, 86% coverage: 7:155/174 of query aligns to 9:160/178 of 3i9v2
8b6fAI ndutt15 (see paper)
38% identity, 95% coverage: 5:169/174 of query aligns to 26:196/231 of 8b6fAI
P29914 NADH-quinone oxidoreductase chain 2; NADH dehydrogenase I, chain 2; NDH-1, chain 2; EC 7.1.1.- from Paracoccus denitrificans (see paper)
41% identity, 79% coverage: 13:150/174 of query aligns to 29:169/239 of P29914
8qbyE Respiratory complex i from paracoccus denitrificans in msp2n2 nanodiscs
41% identity, 79% coverage: 13:150/174 of query aligns to 29:169/236 of 8qbyE
8e73V2 qcr9 (see paper)
35% identity, 93% coverage: 4:164/174 of query aligns to 24:197/222 of 8e73V2
8x9vO Crystal structure of xanthomonas oryzae pv. Oryzae nadh-quinone oxidoreductase subunits nuoe and nuof
40% identity, 84% coverage: 4:150/174 of query aligns to 12:162/163 of 8x9vO
7a23B Plant mitochondrial respiratory complex i (see paper)
34% identity, 90% coverage: 4:159/174 of query aligns to 24:192/219 of 7a23B
7t2rC Structure of electron bifurcating ni-fe hydrogenase complex hydabcsl in fmn-free apo state (see paper)
38% identity, 83% coverage: 5:149/174 of query aligns to 6:150/152 of 7t2rC
>WP_042119339.1 NCBI__GCF_000092045.1:WP_042119339.1
MTMREKIEEAAARYPDQRSAIMPALRIAQTEHGHLPGPVLEEVANILGVERIWVYELATF
YTLFHTEPVGMFHLQLCDNVSCMLCRSEDLLRHLEEVLGIKKGETTPDRLFTLSTVECLG
ACEMAPVMQVGDDYHGDLDIARIDALLDRLRTEARQPTGADLALAAPPGDYRHV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory