SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_042443297.1 NCBI__GCF_000010725.1:WP_042443297.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

6j2lA Crystal structure of bi-functional enzyme (see paper)
64% identity, 44% coverage: 36:90/126 of query aligns to 124:178/200 of 6j2lA

query
sites
6j2lA
R
 
R
K
 
K
G
 
Y
A
 
A
D
 
D
P
 
P
E
 
E
T
 
T
S
 
S
Y
 
Y
T
 
T
A
 
A
K
 
K
L
 
L
Y
 
Y
S
 
A
R
 
S
G
 
G
T
 
T
A
 
K
K
 
R
I
 
I
A
 
A
Q
 
Q
K
 
K
V
 
V
G
 
G
E
 
E
E
|
E
A
 
G
V
 
V
E
 
E
A
 
T
I
 
A
L
 
L
E
 
A
A
 
A
V
 
T
R
 
V
G
 
H
D
 
D
K
 
R
A
 
F
A
 
E
L
 
L
A
 
T
A
 
N
E
|
E
S
 
A
A
 
S
D
|
D
L
 
L
L
 
M
Y
 
Y
H
 
H

Sites not aligning to the query:

6j2lB Crystal structure of bi-functional enzyme (see paper)
55% identity, 35% coverage: 47:90/126 of query aligns to 120:163/185 of 6j2lB

query
sites
6j2lB
A
 
A
K
 
D
L
 
L
Y
 
Y
S
 
A
R
 
S
G
 
G
T
 
T
A
 
K
K
 
R
I
 
I
A
 
A
Q
 
Q
K
 
K
V
 
V
G
 
G
E
 
E
E
|
E
A
 
G
V
 
V
E
|
E
A
 
T
I
 
A
L
 
L
E
 
A
A
 
A
V
 
T
R
 
V
G
 
H
D
 
D
K
 
R
A
 
F
A
 
E
L
 
L
A
 
T
A
 
N
E
|
E
S
 
A
A
 
S
D
|
D
L
 
L
L
 
M
Y
 
Y
H
 
H

Sites not aligning to the query:

Query Sequence

>WP_042443297.1 NCBI__GCF_000010725.1:WP_042443297.1
MADKKTAAQSAPLSAPLSAPLSAEVLDRLYVTVLARKGADPETSYTAKLYSRGTAKIAQK
VGEEAVEAILEAVRGDKAALAAESADLLYHLLVLWADAGLDPAEVWSRLAHREGTSGIDE
KKSRKA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory