SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_043531902.1 NCBI__GCF_000759345.1:WP_043531902.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
37% identity, 92% coverage: 9:213/222 of query aligns to 9:213/214 of 4ymwC

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4ymwC
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Y
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E
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R
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A
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G
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A
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I
N
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D
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E
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S
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H
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S
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L
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R

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
37% identity, 92% coverage: 9:213/222 of query aligns to 9:213/215 of 4ymtC

query
sites
4ymtC
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K
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L
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L
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C
 
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R

Query Sequence

>WP_043531902.1 NCBI__GCF_000759345.1:WP_043531902.1
MLEFIEFGIEWLPRLLQGVPVTLLLWIIAITLGFFLGLMLCWARVYGNRLFYWISTAYVE
LFRGTPMLVQMFFIYLGLPHVGIVFDAFTAAVIAITLNSAAYQAEYFRGSVLSVPKGQLV
AARACGMSQWQAIRHIMLPQALRRVIPQWSNEAIIELKFTSIAYTIGVVEITAIASDIGS
RTFDFFQVFLWAGIIYLVLTSTVASLLGLLERRTYVPGVTNI

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory