SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_043765527.1 NCBI__GCF_000733765.1:WP_043765527.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

4yerA Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
41% identity, 69% coverage: 1:213/309 of query aligns to 1:215/285 of 4yerA

query
sites
4yerA

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binding adenosine-5'-diphosphate: F14 (≠ Y14), F17 (= F18), N39 (= N40), G40 (= G41), G42 (= G43), K43 (= K44), T44 (= T45), T45 (= T46), T135 (= T134), F136 (≠ L135), S137 (= S136)

7e7oA Cryo-em structure of human abca4 in nrpe-bound state (see paper)
34% identity, 98% coverage: 5:306/309 of query aligns to 823:1118/2003 of 7e7oA

query
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7e7oA

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Sites not aligning to the query:

binding [(2S)-3-[2-[(E)-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenylidene]amino]ethoxy-oxidanyl-phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxy-propyl] (Z)-octadec-9-enoate: 285, 290, 526, 527, 589, 592, 1454

7lkpA Structure of atp-free human abca4 (see paper)
32% identity, 99% coverage: 1:306/309 of query aligns to 743:1044/1941 of 7lkpA

query
sites
7lkpA

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binding Digitonin: H819 (≠ A91), Q863 (≠ M133)

Sites not aligning to the query:

binding Digitonin: 522, 526, 530, 533, 616
binding cholesterol: 9, 10, 13, 617, 1073, 1074, 1076, 1402, 1436, 1487, 1492, 1495, 1496, 1499, 1603

7e7qA Cryo-em structure of human abca4 in atp-bound state (see paper)
33% identity, 97% coverage: 5:303/309 of query aligns to 792:1090/1958 of 7e7qA

query
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7e7qA

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binding adenosine-5'-triphosphate: F801 (≠ Y14), C804 (vs. gap), A808 (= A20), N828 (= N40), G831 (= G43), K832 (= K44), T833 (= T45), T834 (= T46), Q873 (= Q85), S926 (= S136), G928 (= G138)
binding magnesium ion: T833 (= T45), Q873 (= Q85)

Sites not aligning to the query:

binding adenosine-5'-triphosphate: 1671, 1698, 1701, 1702, 1703, 1704, 1743, 1794, 1796
binding magnesium ion: 1703, 1743

8f5bA Human abca4 structure in complex with amp-pnp
33% identity, 97% coverage: 5:303/309 of query aligns to 721:1028/1924 of 8f5bA

query
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8f5bA

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R

T

V

V

L

L

A

V

D

G

G

G

H

R

D

D

V

I

V

E

R

T

E

S

F

L

R

D

A

A

A

V

R

R

S

Q

R

S

I

L

G

G

L

M

V

C

P

P

Q
|
Q

E

H

L

N

T

I

T

L

D

F

A

H

F

H

E

L

T

T

V

V

W

A

A

E

A

H

V

M

R

L

F

F

S

Y

R

A

G

Q

L

L

F

K

G

G

K

K

P

S

R

Q

D

E

A

A

H

Q

L

L

-

E

-

M

E

E

K

A

V

M

L

L

R

E

A

D

L

T

S

G

L

L

W

H

D

H

K

K

R

R

D

N

S

E

Q

E

L

A

M

Q

T
x
D

L

L

S

S

G

G

M

M

K

Q

R

R

R

K

L

L

M

S

I

V

A

A

K

I

A

A

L

F

S

V

H

G

E

D

P

A

K

K

I

V

L

V

F

I

L

L

D

D

E

E

P

P

T

T

A

S

G

G

V

V

D

D

V

P

E

Y

L

S

R

R

D

S

M

I

W

W

E

D

M

L

V

L

R

L

G

K

L

Y

R

R

E

-

T

S

G

G

V

R

T

T

V

I

I

I

L

M

T

S

T

T

H

H

Y

H

I

M

E

D

E

E

A

A

E

D

E

L

M

L

A

G

D

D

R

R

I

I

G

A

I

I

N

A

R

Q

G

G

R

R

I

L

L

Y

L

C

V

S

D

G

E

T

T

P

R

L

A

F

L

L

M

K

D

N

K

C

L

F

G

G

A

T

-

G

-

L

-

Y

-

L

-

T

-

L

-

V

-

R

-

D

R

G

E

D

L

V

R

N

L

E

H

L

L

M

Q

D

E

V

P

V

L

L

P

H

T

H

I

V

P

P

E

E

A

A

V

K

A

L

Q

V

E

E

N

C

L

I

T

-

L

-

S

-

E

-

D

-

G

G

S

Q

E

E

L

L

I

I

F

F

R

L

F

L

-

P

D

N

A

K

S

N

A

F

E

K

Q

H

T

R

G

A

V

Y

A

A

A

S

L

L

L

F

R

R

K

E

L

L

D

E

A

E

-

T

-

L

A

A

G

D

I

L

A

G

F

L

R

S

D

S

L

F

N

G

T

I

R

S

E

D

S

T

S

P

L

L

E

E

I

I

F

F

V

L

S

K

L

V

binding phosphoaminophosphonic acid-adenylate ester: N757 (= N40), G758 (= G41), G760 (= G43), K761 (= K44), T762 (= T45), T763 (= T46), Q802 (= Q85), D853 (≠ T134)
binding magnesium ion: T762 (= T45), Q802 (= Q85)

Sites not aligning to the query:

binding phosphoaminophosphonic acid-adenylate ester: 1652, 1653, 1654, 1655, 1656, 1657, 1697, 1748, 1750
binding magnesium ion: 1657, 1697

5x40A Structure of a cbio dimer bound with amppcp (see paper)
40% identity, 69% coverage: 1:213/309 of query aligns to 1:219/280 of 5x40A

query
sites
5x40A

M

M

S

T

S

P

I

I

I

L

S

A

V

A

E

E

R

A

L

L

N

T

K

Y

T

A

Y
x
F

A

P

S

G

G

G

F
x
V

R

K

A
|
A

L

L

R

D

D

D

I

L

D

S

L

L

A

A

I

V

E

P

E

K

G

G

E

E

I

S

F

L

A

A

L

I

L

L

G

G

P

P

N
|
N

G
|
G

A

A

G
|
G

K
|
K

T
x
S

T
|
T

L

L

I

L

S

L

I

H

I

L

C

N

G

G

L

T

V

L

N

R

P

P

S

Q

G

S

G

G

R

R

V

V

L

L

-

L

-

G

-

T

A

A

D

T

G

G

H

H

D

S

V

R

V

-

R

K

E

D

F

L

R

T

A

G

A

W

R

R

S

R

R

R

I

V

G

G

L

L

V

V

P

L

Q
|
Q

E

D

L

A

T

D

D

Q

A

L

F

F

E

A

T

T

-

T

V

V

W

F

A

E

A

D

V

V

R

S

F

F

S

G

R

P

G

L

L

N

F

L

G

G

K

L

P

S

R

E

D

A

D

E

A

A

H

R

-

A

-

R

L

V

E

E

K

E

V

A

L

L

R

A

A

A

L

L

S

S

L

I

W

S

D

D

K

L

R

R

D

D

S

R

Q

P

L

T

M
x
H

T
x
M

L
|
L

S
|
S

G

G

G
|
G

M
x
Q

K

K

R

R

L

V

M

A

I

I

A

A

K

G

A

A

L

V

S

A

H

M

E

R

P

P

K

E

I

V

L

L

F

L

L

L

D

D

E
x
Q

P

P

T

T

A

A

G

G

V

L

D

D

V

L

E

A

L

G

R

T

R

E

D

Q

M

L

W

L

E

T

M

L

V

L

R

R

G

G

L

L

R

R

E

A

T

A

G

G

V

M

T

T

V

L

I

V

L

F

T

S

T

T

H
|
H

Y

D

I

V

E

E

E

L

A

A

E

A

M

L

A

A

D

D

R

R

I

V

G

A

I

L

I

F

N

R

R

T

G

G

R

R

I

V

L

L

binding phosphomethylphosphonic acid adenylate ester: F14 (≠ Y14), V18 (≠ F18), A20 (= A20), N40 (= N40), G41 (= G41), G43 (= G43), K44 (= K44), S45 (≠ T45), T46 (= T46), Q88 (= Q85), H139 (≠ M133), M140 (≠ T134), L141 (= L135), S142 (= S136), G144 (= G138), Q145 (≠ M139), Q166 (≠ E160), H198 (= H192)
binding magnesium ion: S45 (≠ T45), Q88 (= Q85)

7m1qA Human abca4 structure in complex with n-ret-pe (see paper)
33% identity, 91% coverage: 24:303/309 of query aligns to 825:1099/1911 of 7m1qA

query
sites
7m1qA

I

L

D

N

L

I

A

T

I

F

E

Y

E

E

G

N

E

Q

I

I

F

T

A

A

L

F

L

L

G

G

P

H

N

N

G

G

A

A

G

G

K

K

T

T

L

T

I

L

S

S

I

I

I

L

C

T

G

G

L

L

V

L

N

P

P

P

S

T

G

S

G

G

R

T

V

V

L

L

A

V

D

G

G

G

H

R

D

D

V

I

V

E

R

T

E

S

F

L

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D

A

A

A

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R

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Q

R

S

I

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G

G

L

M

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P

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Q

E

H

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N

T

I

T

L

D

F

A

H

F

H

E

L

T

T

V

V

W

A

A

E

A

H

V

M

R

L

F

F

S

Y

R

A

G

Q

L

L

F

K

G

G

K

K

P

S

R

Q

D

E

A

A

H

Q

L

L

-

E

-

M

E

E

K

A

V

M

L

L

R

E

A

D

L

T

S

G

L

L

W

H

D

H

K

K

R

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N

S

E

Q

E

L

A

M

Q

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D

L

L

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S

G

G

M

M

K

Q

R

R

R

K

L

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M

S

I

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A

A

K

I

A

A

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F

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V

H

G

E

D

P

A

K

K

I

V

L

V

F

I

L

L

D

D

E

E

P

P

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T

A

S

G

G

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I

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M

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K

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Y

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E

-

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I

I

I

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T

S

T

T

H

H

Y

H

I

M

E

D

E

E

A

A

E

D

E

L

M

L

A

G

D

D

R

R

I

I

G

A

I

I

N

A

R

Q

G

G

R

R

I

L

-

Y

-

C

-

S

-

G

-

T

-

P

-

L

-

F

-

L

-

K

-

N

-

C

-

G

-

L

-

Y

-

L

-

T

L

L

V

D

D

G

E

D

T

V

R

N

A

E

L

L

M

M

D

D

K

V

L

V

G

-

A

-

R

-

E

-

L

-

R

-

L

-

H

-

L

-

Q

-

E

-

P

-

L

L

P

H

T

H

I

V

P

P

E

E

A

C

V

I

A

G

Q

Q

E

-

N

-

L

-

T

-

L

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-

E

-

D

-

G

-

S

-

E

E

L

L

I

I

F

F

R

K

F

-

D

-

A

-

S

N

A

F

E

K

Q

H

T

R

G

A

V

Y

A

A

A

S

L

L

L

F

R

R

K

E

L

L

D

E

A

E

-

T

-

L

A

A

G

D

I

L

A

G

F

L

R

S

D

S

L

F

N

G

T

I

R

S

E

D

S

T

S

P

L

L

E

E

I

I

F

F

V

L

S

K

L

V

Sites not aligning to the query:

7lkzA Structure of atp-bound human abca4 (see paper)
33% identity, 97% coverage: 5:303/309 of query aligns to 709:1022/1920 of 7lkzA

query
sites
7lkzA

I

V

S

C

V

V

E

K

R

N

L

L

N

V

K

K

T

I

Y
x
F

A

E

S

P

-

C

G

G

F

R

R

P

A
|
A

L

V

R

D

D

R

I

L

D

N

L

I

A

T

I

F

E

Y

E

E

G

N

E

Q

I

I

F

T

A

A

L

F

L

L

G

G

P

H

N
|
N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

T

T

L

T

I

L

S

S

I

I

I

L

C

T

G

G

L

L

V

L

N

P

P

P

S

T

G

S

G

G

R

T

V

V

L

L

A

V

D

G

G

G

H

R

D

D

V

I

V

E

R

T

E

S

F

L

R

D

A

A

A

V

R

R

S

Q

R

S

I

L

G

G

L

M

V

C

P

P

Q
|
Q

E

H

L

N

T

I

T

L

D

F

A

H

F

H

E

L

T

T

V

V

W

A

A

E

A

H

V

M

R

L

F

F

S

Y

R

A

G

Q

L

L

F

K

G

G

K

K

P

S

R

Q

D

E

A

A

H

Q

L

L

-

E

-

M

E

E

K

A

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M

L

L

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E

A

D

L

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S

G

L

L

W

H

D

H

K
|
K

R

R

D

N

S

E

Q

E

L

A

M

Q

T
x
D

L

L

S
|
S

G

G

M

M

K

Q

R

R

R

K

L

L

M

S

I

V

A

A

K

I

A

A

L

F

S

V

H

G

E

D

P

A

K

K

I

V

L

V

F

I

L

L

D

D

E

Q

P

P

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T

A

S

G

G

V

V

D

D

V

P

E

Y

L

S

R

R

D

S

M

I

W

W

E

D

M

L

V

L

R

L

G

K

L

Y

R

R

E

-

T

S

G

G

V

R

T

T

V

I

I

I

L

M

T

S

T

T

H

H

Y

H

I

M

E

D

E

E

A

A

E

D

E

L

M

L

A

G

D

D

R

R

I

I

G

A

I

I

N

A

R

Q

G

G

R

R

I

L

L

Y

L

C

V

S

D

G

E

T

T

P

R

L

A

F

L

L

M

K

D

N

K

C

L

F

G

G

A

T

-

G

-

L

-

Y

-

L

-

T

-

L

-

V

R

R

E

K

L

M

R

K

L

Q

H

V

L

L

Q

D

E

G

P

D

-

V

-

N

-

E

-

L

-

M

-

D

-

V

L

L

P

H

T

H

I

V

P

P

E

E

A

A

V

K

A

L

Q

V

E

E

N

C

L

I

T

-

L

-

S

-

E

-

D

-

G

G

S

Q

E

E

L

L

I

I

F

F

R

L

F

L

-

P

D

N

A

K

S

N

A

F

E

K

Q

H

T

R

G

A

V

Y

A

A

A

S

L

L

L

F

R

R

K

E

L

L

D

E

A

E

-

T

-

L

A

A

G

D

I

L

A

G

F

L

R

S

D

S

L

F

N

G

T

I

R

S

E

D

S

T

S

P

L

L

E

E

I

I

F

F

V

L

S

K

L

V

binding adenosine-5'-triphosphate: F718 (≠ Y14), A725 (= A20), N745 (= N40), G746 (= G41), G748 (= G43), K749 (= K44), T750 (= T45), K834 (= K127), D841 (≠ T134), S843 (= S136)
binding magnesium ion: T750 (= T45), Q790 (= Q85)

Sites not aligning to the query:

binding [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate: 22, 465, 566, 567, 568, 572, 592, 593, 595, 1076, 1355, 1362, 1470, 1471
binding adenosine-5'-triphosphate: 1619, 1646, 1647, 1649, 1650, 1651, 1652, 1742, 1744, 1745

Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see paper)
34% identity, 96% coverage: 5:301/309 of query aligns to 530:837/1704 of Q8R420

query
sites
Q8R420

I

I

S

K

V

I

E

K

R

H

L

L

N

S

K

K

T

V

Y

F

A

Q

S

V

G

G

F

N

R

K

-

D

-

K

-

M

A

G

L

I

R

R

D

D

I

L

D

T

L

L

A

N

I

L

E

Y

E

E

G

G

E

Q

I

I

F

T

A

V

L

L

G

G

P

H

N

N

G

G

A

A

G

G

K

K

T

T

L

T

I

M

S

S

I

L

C

T

G

G

L

L

V

F

N

P

P

P

S

T

G

S

G

G

R

H

V

A

L

Y

A

I

D

H

G

G

H

Y

D

E

V

I

V

S

R

Q

E

D

F

M

R

A

A

Q

A

I

R

R

S

K

R

S

I

L

G

G

L

L

V

C

P

P

Q

Q

E

H

L

D

T

V

T

L

D

F

A

D

F

N

E

L

T

T

V

V

W

A

A

E

A

H

V

L

R

Y

F

F

S

Y

R

A

G

Q

L

L

F

K

G

G

K

L

P

S

R

L

D

Q

D

K

A

C

-

P

-

E

H

E

L

V

E

K

K

Q

V

M

L

L

R

H

A

I

L

L

S

S

L

L

W

E

D

D

K

K

R

R

D

D

S

L

Q

R

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Sites not aligning to the query:

292 E→V: Knockin new born mice are healthy and survive into adulthood without overt signs of respiratory distress. Knockin mice show a severe lung phenotype that begins with alveolar inflammatory cell infiltration at the early stage of the mouse life followed by aberrant lung remodeling with characteristics of diffuse parenchymal lung disease (DPLD)- and emphysema-like alveolar disruption in older mice.

8ee6A Cryo-em structure of human abca7 in pe/ch nanodiscs (see paper)
36% identity, 98% coverage: 1:304/309 of query aligns to 620:932/1808 of 8ee6A

query
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binding phosphothiophosphoric acid-adenylate ester: F633 (≠ Y14), A640 (= A20), N660 (= N40), G661 (= G41), G663 (= G43), K664 (= K44), T665 (= T45), T666 (= T46)

Sites not aligning to the query:

binding phosphothiophosphoric acid-adenylate ester: 607, 608, 1507, 1514, 1535, 1536, 1537, 1538, 1539

Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 15 papers)
34% identity, 96% coverage: 5:301/309 of query aligns to 530:837/1704 of Q99758

query
sites
Q99758

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N568 (= N40) to D: in SMDP3; does not affect location in intracellular vesicle membrane; does not affect proteolytic cleavage; does not affect N-glycosylation; loss of ATP hydrolysis activity; decreases ATP binding in vitro; does not affect protein expression; does not affect multivesicular bodies and lamellar bodies location; affects multivesicular bodies and lamellar bodies development; loss of phosphatidylcholine transport; does not affect cholesterol transport; dbSNP:rs121909184
L579 (≠ I51) to P: in SMDP3; uncertain significance
R605 (= R77) to Q: in SMDP3; uncertain significance; dbSNP:rs760006956
S693 (≠ A163) mutation to L: Does not affect protein oligomerization.
P766 (= P237) to S: in dbSNP:rs45592239
E801 (≠ F263) to D: in a breast cancer sample; somatic mutation

Sites not aligning to the query:

43 R → L: in SMDP3; uncertain significance
53 N→Q: Does not affect N-glycosylation. Does not affect protein expression. Does not affect lamellar body membrane location.
101 L → P: in SMDP3; loss of intracellular vesicle membrane location; loss of proteolytic cleavage; does not affect N-glycosylation; loss of ATP hydrolysis activity; decreases ATP binding in vitro; dbSNP:rs121909182
124 modified: carbohydrate, N-linked (GlcNAc...) asparagine; N→Q: Loss of N-glycosylation. Reduces protein expression by 50%. Affects anterograde trafficking; when associated with Q-140. Reduces protein expression by 85%; when associated with Q-140. Does not affect lamellar body membrane location.
140 modified: carbohydrate, N-linked (GlcNAc...) asparagine; N → H: in dbSNP:rs45447801; N→Q: Loss of N-glycosylation. Reduces protein expression by 50%. Affects anterograde trafficking; when associated with Q-124. Reduces protein expression by 85%; when associated with Q-140. Does not affect lamellar body membrane location.
173:174 LK→AA: Loss of proteolytic processing.
174:175 Cleavage; by CTSL
215 Q → K: in SMDP3; loss of lamellar bodies membrane location; loss of proteolytic cleavage; increases cellular free cholesterol and phosphatidylcholine transport; loss of vesicles formation; increases free cholesterol induced cell death; loss of protein oligomerization; dbSNP:rs879159551
280 R → C: in SMDP3; uncertain significance; does not affect protein oligomerization; dbSNP:rs201299260
288 R → K: in SMDP3; uncertain significance; does not affect protein oligomerization; dbSNP:rs117603931
290 L → M: in a breast cancer sample; somatic mutation
292 E → V: in SMDP3; uncertain significance; does not affect lamellar bodies membrane location; does not affect proteolytic cleavage; affects lamellar bodies formation; does not affect cholesterol and phosphatidylcholine transport; decreases vesicles formation; does not affect free cholesterol induced cell death; dbSNP:rs149989682
945 N→Q: Does not affect lamellar body membrane location. Does not affect protein expression. Does not affect proteolytic processing.
982 L → P: in SMDP3; loss of intracellular vesicle membrane location; loss of proteolytic cleavage; does not affect N-glycosylation; dbSNP:rs1402761450
1069 H → Q: in a breast cancer sample; somatic mutation
1076 N → K: in SMDP3; uncertain significance
1221 G → S: in SMDP3; does not affect intracellular vesicle membrane location; does not affect proteolytic cleavage; does not affect N-glycosylation; loss of ATP hydrolysis activity; G→A: Decreases ATP hydrolysis activity of 15% compared to the wild-type.; G→T: Decreases ATP hydrolysis activity of 36% compared to the wild-type.; G→V: Decreases ATP hydrolysis activity of 18% compared to the wild-type.
1302 G → E: in SMDP3; uncertain significance
1388 K → N: in SMDP3; decreases phosphatidylcholine transport; increases protein abundance; does not affect folding in the endoplasmic reticulum; decreases proteolytic processing; affects lamellar bodies development; reduces free cholesterol transport
1553 L → P: in SMDP3; loss of intracellular vesicle membrane location; loss of proteolytic cleavage; does not affect N-glycosylation; dbSNP:rs121909183
1580 L → P: in SMDP3; does not affect location in intracellular vesicle membrane; does not affect proteolytic cleavage; does not affect N-glycosylation; loss of ATP hydrolysis activity; decreases ATP binding in vitro; affects the intracellular vesicles development; decreases phosphatidylcholine transport; L→A: Decreases ATP hydrolysis activity of 13% compared to the wild-type.; L→F: Decreases ATP hydrolysis activity of 13% compared to the wild-type.; L→V: Decreases ATP hydrolysis activity of 56% compared to the wild-type.
1591 Q → P: in SMDP3; loss of intracellular vesicle membrane location; loss of proteolytic cleavage; does not affect N-glycosylation; dbSNP:rs28936691

7w02A Cryo-em structure of atp-bound abca3 (see paper)
33% identity, 96% coverage: 5:301/309 of query aligns to 495:802/1566 of 7w02A

query
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K

K

K

L

Q

D

K

A

E

A

L

G

G

I

I

A

A

F

-

R

-

D

S

L

F

N

G

T

A

R

S

E

I

S

T

L

M

E

E

I

V

F

F

V

L

binding adenosine-5'-triphosphate: F504 (≠ Y14), N533 (= N40), G534 (= G41), G536 (= G43), K537 (= K44), T538 (= T45), T539 (= T46), Q578 (= Q85), L630 (= L135), S631 (= S136)
binding magnesium ion: T538 (= T45), Q578 (= Q85)

Sites not aligning to the query:

binding adenosine-5'-triphosphate: 1277, 1305, 1306, 1307, 1308, 1309, 1310, 1344, 1395, 1398
binding magnesium ion: 1310, 1344

P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 43 papers)
38% identity, 67% coverage: 5:212/309 of query aligns to 929:1138/2273 of P78363

query
sites
P78363

I
x
V

S
x
C

V
|
V

E
x
K

R
x
N

L
|
L

N
x
V

K
|
K

T
x
I

Y
x
F

A
x
E

S
x
P

-
x
C

G
|
G

F
x
R

R
x
P

A
|
A

L
x
V

R
x
D

D
x
R

I
x
L

D
x
N

L
x
I

A
x
T

I
x
F

E
x
Y

E
|
E

G
x
N

E
x
Q

I
|
I

F
x
T

A
|
A

L
x
F

L
|
L

G
|
G

P
x
H

N
|
N

G
|
G

A
|
A