SitesBLAST
Comparing WP_043920125.1 NCBI__GCF_000877395.1:WP_043920125.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3lxdA Crystal structure of ferredoxin reductase arr from novosphingobium aromaticivorans (see paper)
33% identity, 41% coverage: 29:359/810 of query aligns to 31:368/409 of 3lxdA
- active site: R44 (= R42), P45 (≠ I43), N302 (≠ Y290)
- binding flavin-adenine dinucleotide: R36 (≠ A34), E37 (= E35), R44 (= R42), P45 (≠ I43), S48 (= S46), K49 (≠ P47), E81 (≠ R78), V82 (= V79), T109 (= T106), I157 (≠ L152), G278 (= G273), D279 (≠ E274), S297 (vs. gap), V298 (= V286), F325 (= F307), W326 (≠ A308)
Sites not aligning to the query:
6pfzA Structure of a NAD-dependent persulfide reductase from a. Fulgidus (see paper)
33% identity, 33% coverage: 60:327/810 of query aligns to 66:346/541 of 6pfzA
- binding calcium ion: D306 (= D291), T332 (≠ A313)
- binding coenzyme a: K76 (≠ G70), R313 (≠ K294)
- binding flavin-adenine dinucleotide: A86 (vs. gap), A115 (= A105), T116 (= T106), G117 (= G107), L136 (≠ Y126), G286 (= G273), D287 (≠ E274), P303 (= P288), F304 (≠ L289), G305 (≠ Y290)
Sites not aligning to the query:
- active site: 37, 42, 455, 456
- binding calcium ion: 427, 428
- binding coenzyme a: 14, 18, 21, 38, 40, 42, 430, 447, 512, 513, 516
- binding flavin-adenine dinucleotide: 7, 11, 32, 33, 41, 42
3kljA Crystal structure of nadh:rubredoxin oxidoreductase from clostridium acetobutylicum (see paper)
28% identity, 46% coverage: 2:377/810 of query aligns to 2:359/378 of 3kljA
- active site: P12 (≠ M12), R41 (= R42), P42 (≠ I43), N274 (≠ Y290)
- binding flavin-adenine dinucleotide: L8 (≠ V8), G9 (= G9), G11 (= G11), P12 (≠ M12), A13 (= A13), N32 (= N33), S33 (≠ A34), E34 (= E35), R41 (= R42), P42 (≠ I43), F77 (≠ R78), A78 (≠ V79), S105 (≠ T106), G106 (= G107), L123 (≠ V123), Y124 (≠ I124), L150 (= L152), G257 (= G273), D258 (≠ E274), G268 (= G284), L269 (= L285), I270 (≠ V286), A273 (≠ L289), K301 (= K317)
Q9AL95 NADH-rubredoxin oxidoreductase; NROR; NADH:rubredoxin oxidoreductase; EC 1.18.1.1 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W) (see paper)
28% identity, 46% coverage: 2:377/810 of query aligns to 3:360/379 of Q9AL95
- C26 (≠ G25) modified: Disulfide link with 286
- NSE 33:35 (≠ NAE 33:35) binding FAD
- R42 (= R42) binding FAD
- A79 (≠ V79) binding FAD
- Y125 (≠ I124) binding FAD
- C137 (≠ R133) modified: Disulfide link with 216
- C216 (≠ L231) modified: Disulfide link with 137
- D259 (≠ E274) binding FAD
- C286 (≠ A301) modified: Disulfide link with 26
8c0zE Cryoem structure of a tungsten-containing aldehyde oxidoreductase from aromatoleum aromaticum (see paper)
30% identity, 48% coverage: 6:394/810 of query aligns to 4:405/424 of 8c0zE
Q9HTK9 Rubredoxin-NAD(+) reductase; RdxR; EC 1.18.1.1 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
33% identity, 39% coverage: 5:323/810 of query aligns to 7:326/384 of Q9HTK9
- TGLA 12:15 (≠ GGMA 10:13) binding FAD
- TA 36:37 (≠ NA 33:34) binding FAD
- K45 (≠ R42) binding FAD
- V83 (= V79) binding FAD
- E159 (= E155) binding FAD
- D277 (≠ E274) binding FAD
- V289 (= V286) binding FAD
- K320 (= K317) binding FAD
2v3aA Crystal structure of rubredoxin reductase from pseudomonas aeruginosa. (see paper)
33% identity, 39% coverage: 5:323/810 of query aligns to 4:323/381 of 2v3aA
- active site: L11 (≠ M12), K42 (≠ R42), P43 (≠ I43), M290 (≠ Y290)
- binding flavin-adenine dinucleotide: I7 (≠ V8), G8 (= G9), T9 (≠ G10), G10 (= G11), A12 (= A13), T33 (≠ N33), A34 (= A34), D35 (≠ E35), K42 (≠ R42), P43 (≠ I43), R79 (= R78), V80 (= V79), A105 (= A105), W106 (≠ T106), G107 (= G107), I153 (≠ L152), F157 (≠ A156), D274 (≠ E274), L284 (≠ G284), Y285 (≠ L285), V286 (= V286), K317 (= K317)
6rvhA Nadh-dependent coenzyme a disulfide reductase soaked with menadione (see paper)
33% identity, 36% coverage: 39:330/810 of query aligns to 40:335/443 of 6rvhA
- active site: C44 (≠ I43), E53 (≠ D52), E58 (= E56), Y159 (≠ L151), E163 (= E155)
- binding coenzyme a: S40 (≠ T39), Y41 (= Y40), C44 (≠ I43), R63 (≠ H61), N303 (vs. gap), R307 (≠ K294)
- binding flavin-adenine dinucleotide: A43 (≠ R42), C44 (≠ I43), V81 (= V79), T113 (= T106), G114 (= G107), R134 (= R127), Y159 (≠ L151), G280 (= G273), D281 (≠ E274), P297 (= P288), L298 (= L289), G299 (≠ Y290)
Sites not aligning to the query:
- active site: 39, 425, 430
- binding coenzyme a: 20, 23, 359, 431, 437, 441, 442
- binding flavin-adenine dinucleotide: 8, 11, 12, 13, 34, 35, 424, 425
- binding menadione: 364, 365, 430, 431
6rvbA Nadh-dependent coenzyme a disulfide reductase soaked with nadh (see paper)
33% identity, 36% coverage: 39:330/810 of query aligns to 40:335/443 of 6rvbA
- active site: C44 (≠ I43), E53 (≠ D52), E58 (= E56), Y159 (≠ L151), E163 (= E155)
- binding coenzyme a: S40 (≠ T39), Y41 (= Y40), C44 (≠ I43), R63 (≠ H61), N303 (vs. gap), R307 (≠ K294)
- binding flavin-adenine dinucleotide: A43 (≠ R42), C44 (≠ I43), E80 (≠ R78), V81 (= V79), T113 (= T106), G114 (= G107), L133 (≠ Y126), R134 (= R127), I160 (≠ L152), G280 (= G273), D281 (≠ E274), L298 (= L289), G299 (≠ Y290)
- binding nicotinamide-adenine-dinucleotide: G156 (= G148), G158 (= G150), Y159 (≠ L151), I160 (≠ L152), E179 (≠ H171), A180 (≠ L172), A240 (= A235), T241 (≠ V236), G242 (= G237), P297 (= P288), I328 (≠ L323), F329 (= F324)
Sites not aligning to the query:
- active site: 39, 425, 430
- binding coenzyme a: 15, 20, 23, 359, 437, 441, 442
- binding flavin-adenine dinucleotide: 8, 11, 12, 13, 33, 34, 35, 36, 424, 425
6ruzA Nadh-dependent coenzyme a disulfide reductase (see paper)
33% identity, 36% coverage: 39:330/810 of query aligns to 40:335/443 of 6ruzA
- active site: C44 (≠ I43), E53 (≠ D52), E58 (= E56), Y159 (≠ L151), E163 (= E155)
- binding coenzyme a: S40 (≠ T39), Y41 (= Y40), C44 (≠ I43), R63 (≠ H61), N303 (vs. gap), R307 (≠ K294)
- binding flavin-adenine dinucleotide: A43 (≠ R42), C44 (≠ I43), E80 (≠ R78), V81 (= V79), T113 (= T106), G114 (= G107), A115 (≠ S108), L133 (≠ Y126), R134 (= R127), Y159 (≠ L151), G280 (= G273), D281 (≠ E274), P297 (= P288), L298 (= L289), G299 (≠ Y290)
Sites not aligning to the query:
- active site: 39, 425, 430
- binding coenzyme a: 15, 19, 20, 23, 359, 441, 442
- binding flavin-adenine dinucleotide: 8, 11, 12, 13, 33, 34, 35, 424, 425
3fg2P Crystal structure of ferredoxin reductase for the cyp199a2 system from rhodopseudomonas palustris (see paper)
32% identity, 37% coverage: 6:302/810 of query aligns to 4:309/404 of 3fg2P
- binding flavin-adenine dinucleotide: G8 (= G10), G10 (≠ M12), H11 (≠ A13), A12 (= A14), D34 (≠ A34), E35 (= E35), R42 (= R42), P43 (≠ I43), S46 (= S46), K47 (≠ P47), R78 (= R78), M79 (≠ V79), T106 (= T106), R127 (= R127), I153 (≠ L152), D275 (≠ E274), S292 (≠ L285), V293 (= V286)
Sites not aligning to the query:
1q1wA Crystal structure of putidaredoxin reductase from pseudomonas putida (see paper)
31% identity, 44% coverage: 4:360/810 of query aligns to 5:372/422 of 1q1wA
- active site: L13 (≠ M12), L44 (≠ R42), P45 (≠ I43), L305 (≠ Y290)
- binding flavin-adenine dinucleotide: G10 (= G9), G12 (= G11), L13 (≠ M12), A14 (= A13), G35 (≠ N33), D36 (≠ A34), L44 (≠ R42), P45 (≠ I43), K49 (≠ P47), V82 (= V79), A108 (= A105), T109 (= T106), G110 (= G107), R133 (vs. gap), I159 (≠ L152), D283 (≠ E274), S300 (vs. gap), V301 (= V286), W329 (≠ A308)
P16640 Putidaredoxin reductase CamA; Pdr; Putidaredoxin--NAD(+) reductase; EC 1.18.1.5 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
31% identity, 44% coverage: 4:360/810 of query aligns to 6:373/422 of P16640