SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_044621547.1 NCBI__GCF_000940995.1:WP_044621547.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

1g6hA Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
30% identity, 86% coverage: 42:283/283 of query aligns to 4:254/254 of 1g6hA

query
sites
1g6hA

L

I

L

L

Y

R

V

T

E

E

G

N

V

I

N

V

K

K

S

Y

F
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F

D

G

G

E

F
|
F

K

K

A

A

I

L

D

D

D

G

L

V

N

S

L

I

Y

S

V

V

R

N

E

K

G

G

E

D

L

V

R

T

C

L

I

I

G

G

P

P

N
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N

G
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G

A

S

G
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G

K
|
K

T
x
S

T
|
T

M

L

M

I

D

N

I

V

I

I

T

T

G

G

K

F

T

L

K

K

P

A

D

D

S

E

G

G

Q

R

V

V

W

Y

L

F

G

-

A

E

N

N

I

K

N

D

L

I

L

T

T

N

M

K

N

E

E

P

S

A

Q

E

I

L

A

Y

N

H

A

Y

G

G

V

I

G

V

R

R

K

T

F

F

Q

Q

K

T

P

P

T

Q

V

P

I

L

E

K

C

E

L

M

S

T

V

V

W

L

Q

E

N

N

L

L

E

L

L

I

A

G

-

E

-

I

M

C

S

P

G

G

V

E

R

S

T

P

V

L

W

N

A

S

T

L

Y

F

R

Y

A

K

R

K

L

W

T

I

T

P

E

K

Q

E

K

E

D

E

K

M

L

V

E

E

S

K

V

A

L

F

A

K

L

I

I

L

N

E

L

F

A

L

D

K

N

L

A

S

A

H

L

L

L

Y

-

D

-

R

-

K

A

A

G

G

N

E

L

L

S

S

H

G

G

G

Q

Q

K

M

Q

K

W

L

L

V

E

E

I

I

G

G

M

R

L

A

L

L

M

M

Q

T

N

N

P

P

K

K

L

M

L

I

L

V

V

M

D

D

E

E

P

P

V

I

A

A

-

G

-

V

-

A

-

P

G

G

M

L

T

A

H

H

Q

D

E

I

M

F

D

N

K

H

T

V

A

L

E

E

L

L

L

-

N

-

S

-

L

K

A

A

G

K

K

G

H

I

S

T

V

F

V

L

V

I

E

E

H

H

D

R

M

L

D

D

F

I

V

V

R

L

S

N

I

Y

A

I

S

D

E

H

V

L

T

Y

V

V

L

M

H

F

Q

N

G

G

H

Q

V

I

L

I

A

A

E

E

G

G

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R

-

G

-

E

T

E

M

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K

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N

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V

Q

L

N

S

H

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P

P

E

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V

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Y

Y

L

I

G

G

E

E

binding adenosine-5'-diphosphate: F14 (= F52), F17 (= F55), N39 (= N77), G40 (= G78), G42 (= G80), K43 (= K81), S44 (≠ T82), T45 (= T83)

1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter (see paper)
30% identity, 85% coverage: 42:282/283 of query aligns to 4:253/253 of 1g9xB

query
sites
1g9xB

L

I

L

L

Y

R

V

T

E

E

G

N

V

I

N

V

K

K

S

Y

F
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F

D

G

G

E

F
|
F

K

K

A

A

I

L

D

D

D

G

L

V

N

S

L

I

Y

S

V

V

R

C

E

K

G

G

E

D

L

V

R

T

C

L

I

I

G

G

P

P

N

N

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

M

L

M

I

D

N

I

V

I

I

T

T

G

G

K

F

T

L

K

K

P

A

D

D

S

E

G

G

Q

R

V

V

W

Y

L

F

G

-

A

E

N

N

I

K

N

D

L

I

L

T

T

N

M

K

N

E

E

P

S

A

Q

E

I

L

A

Y

N

H

A

Y

G

G

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I

G

V

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R

K

T

F

F

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Q

K

T

P

P

T

Q

V

P

I

L

E

K

C

E

L

M

S

T

V

V

W

L

Q

E

N

N

L

L

E

L

L

I

A

G

M

E

-

I

-

N

S

P

G

G

V

E

R

S

T

P

V

L

W

N

A

S

T

L

Y

F

R

Y

A

K

R

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L

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T

I

T

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E

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M

L

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E

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A

L

F

A

K

L

I

I

L

N

E

L

F

A

L

D

K

N

L

A

S

A

H

L

L

L

Y

-

D

-

R

-

K

A

A

G

G

N

E

L

L

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S

H

G

G

G

Q

Q

K

M

Q

K

W

L

L

V

E

E

I

I

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G

M

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L

A

L

L

M

M

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T

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N

P

P

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K

L

M

L

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L

V

V

M

D

D

E
|
E

P

P

V

I

A

A

-

G

-

V

-

A

-

P

G

G

M

L

T

A

H

H

Q

D

E

I

M

F

D

N

K

H

T

V

A

L

E

E

L

L

L

-

N

-

S

-

L

K

A

A

G

K

K

G

H

I

S

T

V

F

V

L

V

I

E

E

H

H

D

R

M

L

D

D

F

I

V

V

R

L

S

N

I

Y

A

I

S

D

E

H

V

L

T

Y

V

V

L

M

H

F

Q

N

G

G

H

Q

V

I

L

I

A

A

E

E

G

G

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R

-

G

-

E

T

E

M

I

D

K

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N

V

V

Q

L

N

S

H

D

P

P

E

K

V

V

K

V

R

E

V

I

Y

Y

L

I

G

G

binding adenosine-5'-diphosphate: F14 (= F52), F17 (= F55), G40 (= G78), S41 (≠ A79), G42 (= G80), K43 (= K81), S44 (≠ T82), T45 (= T83)
binding magnesium ion: S44 (≠ T82), E176 (= E210)

6mjpA Lptb(e163q)fgc from vibrio cholerae (see paper)
30% identity, 86% coverage: 42:283/283 of query aligns to 2:236/240 of 6mjpA

query
sites
6mjpA

L

I

L

L

Y

K

V

A

E

Q

G

H

V

L

N

A

K

K

S

S

F

Y

D

K

G

K

F

R

K

K

A

V

I

V

D

S

D

D

L

V

N

S

L

L

Y

Q

V

V

R

E

E

S

G

G

E

Q

L

I

R

V

C

G

I

L

G

G

P

P

N

N

G

G

A

A

G

G

K

K

T

T

M

S

M

F

D

Y

I

M

I

I

T

V

G

G

K

L

T

V

K

A

P

R

D

D

S

E

G

G

Q

T

V

I

W

T

L

I

G

D

A

D

N

N

-

D

I

I

N

S

L

I

L

L

T

P

M

M

N

H

E

S

S

R

Q

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I

-

A

S

N

R

A

M

G

G

V

I

G

G

R

Y

K

L

F

P

Q

Q

K

E

P

A

T

S

V

I

I

F

E

R

C

K

L

L

S

S

V

V

W

E

Q

D

N

N

L

I

E

-

L

-

A

-

M

M

S

A

G

V

V

L

R

Q

T

T

V

-

W

-

A

-

T

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Y

-

R

R

A

E

R

E

L

L

T

T

T

H

E
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E

Q

E

K

R

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Q

D
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D

K

K

L

L

E

E

S

D

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L

L

L

A

E

L

E

I

F

N

H

L

I

A

Q

D

H

N

I

A

R

A

K

L

S

L

A

A

G

G

M

N

A

L

L

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G

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R

L

V

E

E

I

I

G

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R

L

A

L

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M

A

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A

N

N

P

P

K

Q

L

F

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L

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L

D

D

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P

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F

A

A

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G

M

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H

P

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K

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A

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E

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L

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R

G

D

K

R

H

G

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L

S

G

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V

V

L

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E

D

H

H

D

N

M

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D

R

F

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A

C

S

E

E

K

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A

T

Y

V

I

L

V

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S

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Q

G

G

H

R

V

L

L

I

A

A

E

E

G

G

T

T

M

P

D

Q

Q

D

V

V

Q

L

N

N

H

N

P

E

E

Q

V

V

K

K

R

Q

V

V

Y

Y

L

L

G

G

E

E

binding calcium ion: E111 (= E160), D115 (= D163)

P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
32% identity, 79% coverage: 42:264/283 of query aligns to 4:222/501 of P04983

query
sites
P04983

L

L

Y

Q

V

L

E

K

G

G

V

I

N

D

K

K

S

A

F

F

D

P

G

G

F

V

K

K

A

A

I

L

D

S

D

G

L

A

N

A

L

L

Y

N

V

V

R

Y

E

P

G

G

E

R

L

V

R

M

C

A

I

L

I

V

G

G

P

E

N

N

G

G

A

A

G

G

K
|
K

T

S

T

T

M

M

D

K

I

V

I

L

T

T

G

G

K

I

T

Y

K

T

P

R

D

D

S

A

G

G

Q

T

-

L

V

L

W

W

L

L

G

G

A

K

N

E

I

T

N

T

L

F

L

T

T

G

M

P

N

K

E

S

S

S

Q

Q

I

-

A

-

N

E

A

A

G

G

V

I

G

G

R

I

K

I

F

H

Q

Q

K

E

P

L

T

N

V

L

I

I

E

P

C

Q

L

L

S

T

V

I

W

A

Q

E

N

N

L

I

E

F

L

L

A

G

M

R

S

E

G

F

V

V

-

N

-

R

-

F

-

G

R

K

T

I

V

D

W

W

A

K

T

T

Y

M

R

Y

A

A

R

-

L

-

T

-

E

-

Q

E

K

A

D

D

K

K

L

L

E

-

S

-

V

-

L

L

A

A

L

K

I

L

N

N

L

L

A

R

D

F

N

K

A

S

A

D

L

K

L

L

A

V

G

G

N

D

L

L

S

S

H

I

G

G

Q

D

K

Q

Q

Q

W

M

L

V

E

E

I

I

G

A

M

K

L

V

L

L

M

S

Q

F

N

E

P

S

K

K

L

V

L

I

V

M

D

D

E

E

P

P

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T

A

D

G

A

M

L

T

T

H

D

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T

E

E

M

T

D

E

K

S

T

L

A

F

E

R

L

V

L

I

N

R

S

E

L

L

A

K

G

S

K

Q

-

G

H

R

S

G

V

I

V

V

V

Y

V

I

E

S

H

H

D

R

M

M

D

K

F

E

V

I

R

F

S

E

I

I

A

C

S

D

E

D

V

V

T

T

V

V

L

F

H

R

Q

D

G

G

H

Q

V

F

L

I

A

A

E

E

K43 (= K81) mutation to R: Loss of transport.

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide (see paper)
28% identity, 85% coverage: 43:283/283 of query aligns to 3:236/238 of 6s8nB

query
sites
6s8nB

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F

Y

D

K

G

G

F

R

K

R

A

V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N

N

G

G

A

A

G

G

K

K

T

T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M

L

N

H

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A

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Q

-

I

-

A

A

N

R

A

R

G

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G

R

Y

K

L

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K

E

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A

T

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V

I

I

F

E
x
R

C

R

L

L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A

V

M

L

S

Q

G

-

V

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R

-

T

-

V

-

W

-

A

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T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

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Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L
x
M

A
x
G

G
x
Q

N

S

L

L

S

S

H

G

G

G

Q

E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M

R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E

E

P

P

V

F

A

A

G

G

M

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D

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P

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D

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D

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A

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N

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H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

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E

D

H

H

D

N

M

V

D

R

F

E

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T

R

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S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

L

L

G

G

E

E

binding 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione: R90 (≠ E131), M133 (≠ L181), G134 (≠ A182), Q135 (≠ G183)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp (see paper)
28% identity, 85% coverage: 43:283/283 of query aligns to 3:236/238 of 6s8gA

query
sites
6s8gA

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F
x
Y

D

K

G

G

F
x
R

K

R

A

V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N
|
N

G

G

A

A

G
|
G

K
|
K

T
|
T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M

L

N

H

E

A

S

R

Q

-

I

-

A

A

N

R

A

R

G

G

V

I

G

G

R

Y

K

L

F

P

Q
|
Q

K

E

P

A

T

S

V

I

I

F

E

R

C

R

L

L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A

V

M

L

S

Q

G

-

V

-

R

-

T

-

V

-

W

-

A

-

T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

Q

Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L

M

A

G

G

Q

N
x
S

L

L

S
|
S

H

G

G

G

Q
x
E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M

R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E

E

P

P

V

F

A

A

G

G

M

V

T

D

H

P

Q

I

E

S

M

V

D

I

K

D

T

I

A

K

E

R

L

I

N

E

S

H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

I

V

T

E

D

H

H

D

N

M

V

D

R

F

E

V

T

R

L

S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

L

L

G

G

E

E

binding phosphoaminophosphonic acid-adenylate ester: Y12 (≠ F52), R15 (≠ F55), N37 (= N77), G40 (= G80), K41 (= K81), T42 (= T82), T43 (= T83), Q84 (= Q125), S136 (≠ N184), S138 (= S186), E141 (≠ Q189)

3c4jA Abc protein artp in complex with atp-gamma-s
28% identity, 84% coverage: 42:278/283 of query aligns to 3:233/242 of 3c4jA

query
sites
3c4jA

L

M

L

I

Y

D

V

V

E

H

G

Q

V

L

N

K

K

K

S

S

F
|
F

D

G

G

S

F

L

K

E

A
x
V

I

L

D

K

D

G

L

I

N

N

L

V

Y

H

V

I

R

R

E

E

G

G

E

E

L

V

R

V

C

V

I

V

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

M

F

M

L

D

R

I

C

I

L

T

N

G

L

K

L

T

E

K

D

P

F

D

D

S

E

G

G

Q

E

V

I

W

I

L

I

-

D

G

G

A

I

N

N

I

L

N

K

L

A

L

K

T

D

M

T

N

N

E

L

S

N

Q

K

I

V

A

R

N

E

A

E

G

-

V

V

G

G

R

M

K

V

F

F

Q

Q

K

R

P

F

T

N

V

L

I

F

E

P

C

H

L

M

S

T

V

V

W

L

Q

N

N

N

L

I

E

T

L

L

A

A

M

P

S

M

G

K

V

V

R

R

T

K

V

-

W

W

A

P

T

R

Y

E

R

K

A

A

R

-

L

-

T

-

E

-

Q

-

K

E

D

A

K

K

L

A

E

M

S

E

V

L

L

L

A

D

L

K

I

V

N

G

L

L

A

K

D

D

N

K

A

A

A

H

L

A

L

Y

A

P

G

D

N

S

L

L

S

S

H

G

G

G

Q

Q

K

A

Q

Q

W

R

L

V

E

A

I

I

G

A

M

R

L

A

L

L

M

A

Q

M

N

E

P

P

K

K

L

I

L

M

L

L

V

F

D

D

E

E

P

P

V

T

A

S

G

A

M

L

T

D

H

P

Q

E

E

M

M

V

D

G

K

E

T

V

A

L

E

S

L

V

L

M

N

K

S

Q

L

L

A

A

G

N

K

E

-

G

H

M

S

T

V

M

V

V

E

T

H

H

D

E

M

M

D

G

F

F

V

A

R

R

S

E

I

V

A

G

S

D

E

R

V

V

T

L

V

F

L

M

H

D

Q

G

G

G

H

Y

V

I

L

I

A

E

E

E

G

G

T

K

M

P

D

E

Q

D

V

L

Q

F

N

D

H

R

P

P

E

Q

V

H

K

E

R

R

binding phosphothiophosphoric acid-adenylate ester: F13 (= F52), V18 (≠ A57), S38 (≠ N77), G39 (= G78), S40 (≠ A79), G41 (= G80), K42 (= K81), S43 (≠ T82), T44 (= T83)

3c41J Abc protein artp in complex with amp-pnp/mg2+
28% identity, 84% coverage: 42:278/283 of query aligns to 3:233/242 of 3c41J

query
sites
3c41J

L

M

L

I

Y

D

V

V

E

H

G

Q

V

L

N

K

K

K

S

S

F
|
F

D

G

G

S

F

L

K

E

A
x
V

I

L

D

K

D

G

L

I

N

N

L

V

Y

H

V

I

R

R

E

E

G

G

E

E

L

V

R

V

C

V

I

V

I

I

G

G

P

P

N
x
S

G
|
G

A

S

G
|
G

K
|
K

T
x
S

T
|
T

M

F

M

L

D

R

I

C

I

L

T

N

G

L

K

L

T

E

K

D

P

F

D

D

S

E

G

G

Q

E

V

I

W

I

L

I

-

D

G

G

A

I

N

N

I

L

N

K

L

A

L

K

T

D

M

T

N

N

E

L

S

N

Q

K

I

V

A

R

N

E

A

E

G

-

V

V

G

G

R

M

K

V

F

F

Q

Q

K

R

P

F

T

N

V

L

I

F

E

P

C

H

L

M

S

T

V

V

W

L

Q

N

N

N

L

I

E

T

L

L

A

A

M

P

S

M

G

K

V

V

R

R

T

K

V

-

W

W

A

P

T

R

Y

E

R

K

A

A

R

-

L

-

T

-

E

-

Q

-

K

E

D

A

K

K

L

A

E

M

S

E

V

L

L

L

A

D

L

K

I

V

N

G

L

L

A

K

D

D

N

K

A

A

A

H

L

A

L

Y

A

P

G

D

N

S

L

L

S

S

H

G

G

G

Q

Q

K

A

Q

Q

W

R

L

V

E

A

I

I

G

A

M

R

L

A

L

L

M

A

Q

M

N

E

P

P

K

K

L

I

L

M

L

L

V

F

D
|
D

E

E

P

P

V

T

A

S

G

A

M

L

T

D

H

P

Q

E

E

M

M

V

D

G

K

E

T

V

A

L

E

S

L

V

L

M

N

K

S

Q

L

L

A

A

G

N

K

E

-

G

H

M

S

T

V

M

V

V

E

T

H

H

D

E

M

M

D

G

F

F

V

A

R

R

S

E

I

V

A

G

S

D

E

R

V

V

T

L

V

F

L

M

H

D

Q

G

G

G

H

Y

V

I

L

I

A

E

E

E

G

G

T

K

M

P

D

E

Q

D

V

L

Q

F

N

D

H

R

P

P

E

Q

V

H

K

E

R

R

binding phosphoaminophosphonic acid-adenylate ester: F13 (= F52), V18 (≠ A57), S38 (≠ N77), G39 (= G78), G41 (= G80), K42 (= K81), S43 (≠ T82), T44 (= T83)
binding magnesium ion: S43 (≠ T82), D163 (= D209)

2olkA Abc protein artp in complex with adp-beta-s
28% identity, 84% coverage: 42:278/283 of query aligns to 3:233/242 of 2olkA

query
sites
2olkA

L

M

L

I

Y

D

V

V

E

H

G

Q

V

L

N

K

K

K

S

S

F
|
F

D

G

G

S

F

L

K

E

A
x
V

I

L

D

K

D

G

L

I

N

N

L

V

Y

H

V

I

R

R

E

E

G

G

E

E

L

V

R

V

C

V

I

V

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

M

F

M

L

D

R

I

C

I

L

T

N

G

L

K

L

T

E

K

D

P

F

D

D

S

E

G

G

Q

E

V

I

W

I

L

I

-

D

G

G

A

I

N

N

I

L

N

K

L

A

L

K

T

D

M

T

N

N

E

L

S

N

Q

K

I

V

A

R

N

E

A

E

G

-

V

V

G

G

R

M

K

V

F

F

Q

Q

K

R

P

F

T

N

V

L

I

F

E

P

C

H

L

M

S

T

V

V

W

L

Q

N

N

N

L

I

E

T

L

L

A

A

M

P

S

M

G

K

V

V

R

R

T

K

V

-

W

W

A

P

T

R

Y

E

R

K

A

A

R

-

L

-

T

-

E

-

Q

-

K

E

D

A

K

K

L

A

E

M

S

E

V

L

L

L

A

D

L

K

I

V

N

G

L

L

A

K

D

D

N

K

A

A

A

H

L

A

L

Y

A

P

G

D

N

S

L

L

S

S

H

G

G

G

Q

Q

K

A

Q

Q

W

R

L

V

E

A

I

I

G

A

M

R

L

A

L

L

M

A

Q

M

N

E

P

P

K

K

L

I

L

M

L

L

V

F

D

D

E

E

P

P

V

T

A

S

G

A

M

L

T

D

H

P

Q

E

E

M

M

V

D

G

K

E

T

V

A

L

E

S

L

V

L

M

N

K

S

Q

L

L

A

A

G

N

K

E

-

G

H

M

S

T

V

M

V

V

E

T

H

H

D

E

M

M

D

G

F

F

V

A

R

R

S

E

I

V

A

G

S

D

E

R

V

V

T

L

V

F

L

M

H

D

Q

G

G

G

H

Y

V

I

L

I

A

E

E

E

G

G

T

K

M

P

D

E

Q

D

V

L

Q

F

N

D

H

R

P

P

E

Q

V

H

K

E

R

R

binding 5'-o-[(r)-hydroxy(thiophosphonooxy)phosphoryl]adenosine: F13 (= F52), V18 (≠ A57), S38 (≠ N77), G39 (= G78), S40 (≠ A79), G41 (= G80), K42 (= K81), S43 (≠ T82), T44 (= T83)

2oljA Abc protein artp in complex with adp/mg2+
28% identity, 84% coverage: 42:278/283 of query aligns to 3:233/242 of 2oljA

query
sites
2oljA

L

M

L

I

Y

D

V

V

E

H

G

Q

V

L

N

K

K

K

S

S

F
|
F

D

G

G

S

F

L

K

E

A
x
V

I

L

D

K

D

G

L

I

N

N

L

V

Y

H

V

I

R

R

E

E

G

G

E

E

L

V

R

V

C

V

I

V

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

M

F

M

L

D

R

I

C

I

L

T

N

G

L

K

L

T

E

K

D

P

F

D

D

S

E

G

G

Q

E

V

I

W

I

L

I

-

D

G

G

A

I

N

N

I

L

N

K

L

A

L

K

T

D

M

T

N

N

E

L

S

N

Q

K

I

V

A

R

N

E

A

E

G

-

V

V

G

G

R

M

K

V

F

F

Q

Q

K

R

P

F

T

N

V

L

I

F

E

P

C

H

L

M

S

T

V

V

W

L

Q

N

N

N

L

I

E

T

L

L

A

A

M

P

S

M

G

K

V

V

R

R

T

K

V

-

W

W

A

P

T

R

Y

E

R

K

A

A

R

-

L

-

T

-

E

-

Q

-

K

E

D

A

K

K

L

A

E

M

S

E

V

L

L

L

A

D

L

K

I

V

N

G

L

L

A

K

D

D

N

K

A

A

A

H

L

A

L

Y

A

P

G

D

N

S

L

L

S

S

H

G

G

G

Q

Q

K

A

Q

Q

W

R

L

V

E

A

I

I

G

A

M

R

L

A

L

L

M

A

Q

M

N

E

P

P

K

K

L

I

L

M

L

L

V

F

D

D

E

E

P

P

V

T

A

S

G

A

M

L

T

D

H

P

Q

E

E

M

M

V

D

G

K

E

T

V

A

L

E

S

L

V

L

M

N

K

S

Q

L

L

A

A

G

N

K

E

-

G

H

M

S

T

V

M

V

V

E

T

H

H

D

E

M

M

D

G

F

F

V

A

R

R

S

E

I

V

A

G

S

D

E

R

V

V

T

L

V

F

L

M

H

D

Q

G

G

G

H

Y

V

I

L

I

A

E

E

E

G

G

T

K

M

P

D

E

Q

D

V

L

Q

F

N

D

H

R

P

P

E

Q

V

H

K

E

R

R

binding adenosine-5'-diphosphate: F13 (= F52), V18 (≠ A57), S38 (≠ N77), G39 (= G78), S40 (≠ A79), G41 (= G80), K42 (= K81), S43 (≠ T82), T44 (= T83)

6mbnA Lptb e163q in complex with atp (see paper)
28% identity, 85% coverage: 43:283/283 of query aligns to 4:237/241 of 6mbnA

query
sites
6mbnA

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F
x
Y

D

K

G

G

F
x
R

K

R

A
x
V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N
|
N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M

L

N

H

E

A

S

R

Q

-

I

-

A

A

N

R

A

R

G

G

V

I

G

G

R

Y

K

L

F

P

Q

Q

K

E

P

A

T

S

V

I

I

F

E

R

C

R

L

L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A

V

M

L

S

Q

G

-

V

-

R

-

T

-

V

-

W

-

A

-

T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

Q

Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L

M

A

G

G

Q

N

S

L

L

S

S

H

G

G

G

Q

E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M

R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E

Q

P

P

V

F

A

A

G

G

M

V

T

D

H

P

Q

I

E

S

M

V

D

I

K

D

T

I

A

K

E

R

L

I

N

E

S

H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

I

V

T

E

D

H
|
H

D

N

M

V

D

R

F

E

V

T

R

L

S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

L

L

G

G

E

E

binding adenosine-5'-triphosphate: Y13 (≠ F52), R16 (≠ F55), V18 (≠ A57), N38 (= N77), G39 (= G78), G41 (= G80), K42 (= K81), T43 (= T82), T44 (= T83), H195 (= H241)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter (see paper)
28% identity, 85% coverage: 43:282/283 of query aligns to 3:235/235 of 6mhzA

query
sites
6mhzA

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F
x
Y

D

K

G

G

F

R

K

R

A

V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N
|
N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M

L

N

H

E

A

S

R

Q

-

I

-

A

A

N

R

A

R

G

G

V

I

G

G

R

Y

K

L

F

P

Q
|
Q

K

E

P

A

T

S

V

I

I

F

E

R

C

R

L

L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A

V

M

L

S

Q

G

-

V

-

R

-

T

-

V

-

W

-

A

-

T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

Q

Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L

M

A

G

G

Q

N
x
S

L

L

S
|
S

H
x
G

G
|
G

Q

E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M

R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E
|
E

P

P

V

F

A

A

G
|
G

M

V

T

D

H

P

Q

I

E

S

M

V

D

I

K

D

T

I

A

K

E

R

L

I

N

E

S

H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

I

V

T

E

D

H
|
H

D

N

M

V

D

R

F

E

V

T

R

L

S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

L

L

G

G

binding adp orthovanadate: Y12 (≠ F52), N37 (= N77), G38 (= G78), G40 (= G80), K41 (= K81), T42 (= T82), T43 (= T83), Q84 (= Q125), S136 (≠ N184), S138 (= S186), G139 (≠ H187), G140 (= G188), E162 (= E210), G166 (= G214), H194 (= H241)

6b89A E. Coli lptb in complex with adp and novobiocin (see paper)
28% identity, 84% coverage: 43:281/283 of query aligns to 3:234/234 of 6b89A

query
sites
6b89A

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F
x
Y

D

K

G

G

F
x
R

K

R

A
x
V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N
|
N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M
x
L

N
x
H

E

A

S

R

Q

-

I

-

A

A

N

R

A

R

G

G

V

I

G

G

R

Y

K

L

F
x
P

Q
|
Q

K

E

P
x
A

T
x
S

V

I

I
x
F

E
x
R

C
x
R

L
|
L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A
x
V

M

L

S

Q

G

-

V

-

R

-

T

-

V

-

W

-

A

-

T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

Q

Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L

M

A

G

G
x
Q

N

S

L

L

S

S

H

G

G

G

Q

E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M
x
R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E

E

P

P

V

F

A

A

G

G

M

V

T

D

H

P

Q

I

E

S

M

V

D

I

K

D

T

I

A

K

E

R

L

I

N

E

S

H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

I

V

T

E

D

H

H

D

N

M

V

D

R

F

E

V

T

R

L

S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

L

L

binding adenosine-5'-diphosphate: Y12 (≠ F52), R15 (≠ F55), V17 (≠ A57), N37 (= N77), G38 (= G78), G40 (= G80), K41 (= K81), T42 (= T82), T43 (= T83)
binding magnesium ion: T42 (= T82), Q84 (= Q125)
binding novobiocin: L71 (≠ M110), H72 (≠ N111), P83 (≠ F124), A86 (≠ P127), S87 (≠ T128), F89 (≠ I130), R90 (≠ E131), R91 (≠ C132), L92 (= L133), V101 (≠ A142), Q135 (≠ G183), R149 (≠ M197)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium (see paper)
28% identity, 84% coverage: 43:281/283 of query aligns to 3:234/234 of 4p31A

query
sites
4p31A

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F
x
Y

D

K

G

G

F
x
R

K

R

A
x
V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N

N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M

L

N

H

E

A

S

R

Q

-

I

-

A

A

N

R

A

R

G

G

V

I

G

G

R

Y

K

L

F

P

Q
|
Q

K

E

P

A

T

S

V

I

I

F

E

R

C

R

L

L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A

V

M

L

S

Q

G

-

V

-

R

-

T

-

V

-

W

-

A

-

T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

Q

Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L

M

A

G

G

Q

N

S

L

L

S

S

H

G

G

G

Q

E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M

R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E

E

P

P

V

F

A

A

G

G

M

V

T

D

H

P

Q

I

E

S

M

V

D

I

K

D

T

I

A

K

E

R

L

I

N

E

S

H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

I

V

T

E

D

H

H

D

N

M

V

D

R

F

E

V

T

R

L

S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

L

L

binding adenosine-5'-diphosphate: Y12 (≠ F52), R15 (≠ F55), V17 (≠ A57), G38 (= G78), G40 (= G80), K41 (= K81), T42 (= T82), T43 (= T83)
binding magnesium ion: T42 (= T82), Q84 (= Q125)

4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 81% coverage: 42:270/283 of query aligns to 1:223/240 of 4ymuJ

query
sites
4ymuJ

L

M

L

I

Y

F

V

V

E

N

G

D

V

V

N

Y

K

K

S

N

F
|
F

D

G

G

S

F

L

K

E

A
x
V

I

L

D

K

D

G

L

V

N

T

L

L

Y

K

V

V

R

N

E

K

G

G

E

E

L

V

R

V

C

V

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

M

L

D

R

I

C

I

I

T

N

G

L

K

L

T

E

K

E

P

P

D

T

S

K

G

G

Q

E

V

V

W

F

L

I

-

D

G

G

A

V

N

K

I

I

N

N

L

N

L

G

T

K

M

V

N

N

E

I

S

N

Q

K

I

V

A

R

N

Q

A

K

G

-

V

V

G

G

R

M

K

V

F

F

Q

Q

K

H

P

F

T

N

V

L

I

F

E

P

C

H

L

L

S

T

V

A

W

I

Q

E

N

N

L

I

E

T

L

L

A

A

M

P

S

V

G

K

V

V

R

K

T

K

V

M

W

N

A

K

T

K

Y

E

R

A

A

E

R

E

L

L

T

A

T

V

E

D

Q

-

K

-

D

-

K

-

L

-

E

-

S

-

V

L

L

L

A

A

L

K

I

V

N

G

L

L

A

L

D

D

N

K

A

K

A

D

L

Q

L

Y

A

P

G

I

N

K

L

L

S

S

H

G

G

G

Q

Q

K

K

Q

Q

W

R

L

L

E

A

I

I

G

A

M

R

L

A

L

L

M

A

Q

M

N

Q

P

P

K

E

L

V

L

M

L

L

V

F

D

D

E
|
E

P

P

V

T

A

S

G

A

M

L

T

D

H

P

Q

E

E

M

M

V

D

K

K

E

T

V

A

L

E

N

L

V

L

M

N

K

S

Q

L

L

A

A

G

N

K

E

-

G

H

M

S

T

V

M

V

V

E

T

H
|
H

D

E

M

M

D

G

F

F

V

A

R

R

S

E

I

V

A

G

S

D

E

R

V

V

T

I

V

F

L

M

H

D

Q

D

G

G

H

V

V

I

L

V

A

E

E

E

G

G

T

T

M

P

D

E

Q

E

V

I

binding adenosine-5'-triphosphate: F11 (= F52), V16 (≠ A57), S36 (≠ N77), G37 (= G78), S38 (≠ A79), G39 (= G80), K40 (= K81), S41 (≠ T82), T42 (= T83), E162 (= E210), H194 (= H241)
binding magnesium ion: S41 (≠ T82), E162 (= E210)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative (see paper)
27% identity, 84% coverage: 43:280/283 of query aligns to 3:233/233 of 6b8bA

query
sites
6b8bA

L

L

Y

T

V

A

E

K

G

N

V

L

N

A

K

K

S

A

F
x
Y

D

K

G

G

F
x
R

K

R

A
x
V

I

V

D

E

D

D

L

V

N

S

L

L

Y

T

V

V

R

N

E

S

G

G

E

E

L

I

R

V

C

G

I

L

G

G

P

P

N

N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

M

T

M

F

D

Y

I

M

I

V

T

V

G

G

K

I

T

V

K

P

P

R

D

D

S

A

G

G

Q

N

-

I

V

I

W

I

L

D

G

D

A

D

N

D

I

I

N

S

L

L

T

P

M

L

N

H

E

A

S

R

Q

-

I

-

A

A

N

R

A

R

G

G

V

I

G

G

R

Y

K

L

F

P

Q

Q

K

E

P

A

T

S

V

I

I
x
F

E
x
R

C
x
R

L

L

S

S

V

V

W

Y

Q

D

N

N

L

L

E

M

L

A

A

V

M

L

S

Q

G

-

V

-

R

-

T

-

V

-

W

-

A

-

T

-

Y

I

R

R

A

D

R

D

L

L

T

S

T

A

E

E

Q

Q

K

R

-

E

D

D

K

R

L

A

E

N

S

E

V

L

L

M

A

E

L

E

I

F

N

H

L

I

A

E

D

H

N

L

A

R

A

D

L

S

L

M

A

G

G

Q

N

S

L

L

S

S

H

G

G

G

Q

E

K

R

Q

R

W

R

L

V

E

E

I

I

G

A

M

R

L

A

L

L

M

A

Q

A

N

N

P

P

K

K

L

F

L

I

L

L

V

L

D

D

E

E

P

P

V

F

A

A

G

G

M

V

T

D

H

P

Q

I

E

S

M

V

D

I

K

D

T

I

A

K

E

R

L

I

N

E

S

H

L

L

A

R

G

D

K

S

H

G

-

L

S

G

V

V

V

L

V

I

V

T

E

D

H

H

D

N

M

V

D

R

F

E

V

T

R

L

S

A

I

V

A

C

S

E

E

R

V

A

T

Y

V

I

L

V

H

S

Q

Q

G

G

H

H

V

L

L

I

A

A

E

H

G

G

T

T

M

P

D

T

Q

E

V

I

Q

L

N

Q

H

D

P

E

E

H

V

V

K

K

R

R

V

V

Y

Y

binding adenosine-5'-diphosphate: Y12 (≠ F52), R15 (≠ F55), V17 (≠ A57), G38 (= G78), G40 (= G80), K41 (= K81), T42 (= T82), T43 (= T83)
binding (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide: F89 (≠ I130), R90 (≠ E131), R91 (≠ C132)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation (see paper)
31% identity, 84% coverage: 45:282/283 of query aligns to 5:242/263 of 7d0aB

query
sites
7d0aB

V

I

E

E

G

V

V

K

N

N

K

L

S

S

F

F

D

N

-

R

G

G

F

E

K

R

A

V

I

I

-

Y

D

D

D

N

L

I

N

S

L

L

Y

N

V

I

R

R

E

R

G

G

E

Q

L

I

R

T

C

A

I

I

I

M

G

G

P

P

N
x
S

G

G

A
x
T

G
|
G

K
|
K

T

T

M

L

D

R

I

L

I

I

T

G

G

G

K

Q

T

L

K

V

P

P

D

D

S

Q

G

G

Q

E

V

V

W

L

L

L

-

D

G

G

A

K

N

D

I

I

N

A

L

Q

L

M

T

S

M

R

N

Q

E

E

S

L

Q

F

I

A

A

A

N

R

A

A

G

R

V

M

G

G

R

M

K

L

F

F

Q

Q

K

S

P

G

T

A

V

L

I

F

E

T

C

D

L

M

S

S

V

V

W

Y

Q

E

N

N

L

V

E

A

L

F

A

P

M

I

S

R

G

A

V

H

R

T

T

K

V

L

W

S

A

E

T

N

Y

L

R

I

A

A

R

E

L

L

T

V

T

A

E

L

Q

-

K

-

D

-

K

K

L

L

E

E

S

S

V

V

L

-

A

-

L

-

I

-

N

G

L

L

A

R

D

G

N

T

A

E

A

Q

L

L

L

M

A

P

G

T

N
x
E

L

L

S
|
S

H

G

G

G

Q
x
M

K

N

Q

R

W

R

L

V

E

A

I

L

G

A

M

R

L

A

L

I

M

A

Q

L

N

D

P

P

K

D

L

L

L

I

L

M

V

Y

D

D

E

E

P

P

V

F

A

A

G

G

M

Q

T

D

H

P

Q

I

E

V

M

K

D

G

K

V

T

L

A

T

E

R

L

L

L

I

N

R

S

S

L

L

-

R

-

E

A

A

G

L

K

D

H

L

S

T

V

T

V

I

V

V

E

S

H

H

D

D

M

V

D

P

F

E

V

T

R

L

S

S

I

I

A

A

S

D

E

Y

V

I

T

Y

V

V

L

V

H

A

Q

E

G

G

H

K

V

I

L

Q

A

G

E

E

G

G

T

T

M

P

D

E

Q

E

V

L

Q

Q

N

A

H

Y

-

A

-

S

P

P

E

F

V

V

K

K

R

Q

V

F

Y

L

L

T

G

G

binding adenosine-5'-diphosphate: S39 (≠ N77), T41 (≠ A79), G42 (= G80), K43 (= K81), E140 (≠ N184), S142 (= S186), M145 (≠ Q189)

7d08B Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
31% identity, 84% coverage: 45:282/283 of query aligns to 5:242/263 of 7d08B

query
sites
7d08B

V

I

E

E

G

V

V

K

N

N

K

L

S

S

F

F

D

N

-
x
R

G

G

F

E

K
x
R

A

V

I

I

-

Y

D

D

D

N

L

I

N

S

L

L

Y

N

V

I

R

R

E

R

G

G

E

Q

L

I

R

T

C

A

I

I

I

M

G

G

P

P

N

S

G
|
G

A
x
T

G

G

K
|
K

T
|
T

M

L

D

R

I

L

I

I

T

G

G

G

K

Q

T

L

K

V

P

P

D

D

S

Q

G

G

Q

E

V

V

W

L

L

L

-

D

G

G

A

K

N

D

I

I

N

A

L

Q

L

M

T

S

M

R

N

Q

E

E

S

L

Q

F

I

A

A

A

N

R

A

A

G

R

V

M

G

G

R

M

K

L

F

F

Q

Q

K

S

P

G

T

A

V

L

I

F

E

T

C

D

L

M

S

S

V

V

W

Y

Q

E

N

N

L

V

E

A

L

F

A

P

M

I

S

R

G

A

V

H

R

T

T

K

V

L

W

S

A

E

T

N

Y

L

R

I

A

A

R

E

L

L

T

V

T

A

E

L

Q

-

K

-

D

-

K

K

L

L

E

E

S

S

V

V

L

-

A

-

L

-

I

-

N

G

L

L

A

R

D

G

N

T

A

E

A

Q

L

L

L

M

A

P

G

T

N

E

L

L

S

S

H

G

G

G

Q

M

K

N

Q

R

W

R

L

V

E

A

I

L

G

A

M

R

L

A

L

I

M

A

Q

L

N

D

P

P

K

D

L

L

L

I

L

M

V

Y

D

D

E
|
E

P

P

V

F

A

A

G

G

M

Q

T

D

H

P

Q

I

E

V

M

K

D

G

K

V

T

L

A

T

E

R

L

L

L

I

N

R

S

S

L

L

-

R

-

E

A

A

G

L

K

D

H

L

S

T

V

T

V

I

V

V

E

S

H

H

D

D

M

V

D

P

F

E

V

T

R

L

S

S

I

I

A

A

S

D

E

Y

V

I

T

Y

V

V

L

V

H

A

Q

E

G

G

H

K

V

I

L

Q

A

G

E

E

G

G

T

T

M

P

D

E

Q

E

V

L

Q

Q

N

A

H

Y

-

A

-

S

P

P

E

F

V

V

K

K

R

Q

V

F

Y

L

L

T

G

G

binding adenosine-5'-triphosphate: R14 (vs. gap), R17 (≠ K56), G40 (= G78), T41 (≠ A79), K43 (= K81), T44 (= T82), T45 (= T83), E166 (= E210)

P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
28% identity, 78% coverage: 55:275/283 of query aligns to 18:233/343 of P30750

query
sites
P30750

F

I

K

Q

A

A

I

L

D

N

L

V

N

S

L

L

Y

H

V

V

R

P

E

A

G

G

E

Q

L

I

R

Y

C

G

I

V

I

I

G

G

P

A

N
x
S

G
|
G

A
|
A

G
|
G

K
|
K

T
x
S

T
|
T

M

L

M

I

D

R

I

C

I

V

T

N

G

L

K

L

T

E

K

R

P

P

D

T

S

E

G

G

Q

S

V

V

W

L

L

V

G

D

A

G

N

Q

I

-

N

E

L

L

L

T

T

T

M

L

N

S

E

E

S

S

Q

E

I

L

A

T

N

K

A

A

-

R

G

Q

V

I

G

G

R

M

K

I

F

F

Q

Q

K

H

P

F

T

N

V

L

I

L

E

S

C

S

L

R

S

T

V

V

W

F

Q

G

N

N

L

V

E

A

L

L

A

P

M

L

S

E

G

L

V

D