SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_047215060.1 NCBI__GCF_001931675.1:WP_047215060.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

Q54VI3 Glutamate dehydrogenase 2; NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Dictyostelium discoideum (Social amoeba) (see paper)
24% identity, 31% coverage: 702:1215/1639 of query aligns to 422:906/1042 of Q54VI3

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Q54VI3
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Query Sequence

>WP_047215060.1 NCBI__GCF_001931675.1:WP_047215060.1
MKPARSEDKVAQRLEEAAAFARERDGAAPAAFEAFLRHYFSQADADDVMSRAVPDLYGAA
MAHWQLAQTFPSGNARIRVYNPDVEQSGWYCEHTVVEIVNDDMPFLVDSVTTEINRLGLA
LHSAFHPVFRVWRDVDGQRRRAAPSSTPNREEASGGAPADAGRLESYIHLEVDRCTEAAR
LQALHAGIAKVLGDVRAAVEDWPQMRSAAQQAVAALSARERAAGRAPDEGEEIAEARAFL
AWMIDDHFTFLGQRDYQLVSEQGTYYLQPDQSPGLGILREALRAPGAAERTALAPEAVRV
IEDASPIFLTKANSRATVHRPGYLDYVGVKLFDAAGKVCGERRFLGLYTSSAYMEPTGEI
PLVRRKVAAVVQRAGFLPKGHLAKSLQTILEQYPRDELFQIDSDTLFEIAMGILRLQERQ
RTRLFVRRDRFDRFVSCLVFVPREKFNTDLRLRIQQLLQTAYQGSGVEFTPLLSESMLAR
IHITVRTEPGQVPEVDVRDLEARIVQAARRWQDELADALLERCGEEQGNRLLHRYGGSFP
AGFREDYAARGAVHDIQLMEQIVSQAGARDGALAMHLYRPIEAPPGTLRFKIYQVGRPIA
LSRSLPMLEHLGVLVNEERPYRIEPHDAEPIWIHDFGMQSADGAEVDLTHIKPLFEEAFA
RIWAGDAENDGLNRLVLRAGLKWPEVRILRAYARYMRQIGSTFSDAYMERALTGNPAIAR
LLVSLFQARFDPAMGETHAAAREARVQDLQQQIAAALDDVPNLDEDRILRQFLGVLEATL
RTNDFQRAAQHAPKPYLSLKFDPARVPGLPEPKPMFEIWVYSPRVEGVHLRGGKVARGGL
RWSDRREDFRTEVLGLVKAQMVKNTVIVPVGSKGGFVVKQAPAEREAYLKEGVACYQTFL
RGLLDLTDNLVEGRLVPPPDVVRFDPDDPYLVVAADKGTATFSDYANAISAEYGFWLDDA
FASGGSVGYDHKKMGITARGAWESVKRHFREMGVDTQQTDFTVAGIGDMSGDVFGNAMLL
SRHIRLVAAFDHRHIFLDPAPDPQVSFAERERLFKLPRSSWDDYDRAAISPGGGVFARTV
KSIVLSPQVRAALGVSEAELAPADLMRAILRAPVDLFYNGGIGTYVKASYESHAQVGDRA
NDAVRVDGADLRCKVVAEGGNLGCTQFGRIEFAQRGGRINTDAIDNSAGVDCSDHEVNIK
ILLGLVVADGEMTLKQRNALLASMADEVGELVLRDNYYQTRALSLARDRAPAWLDAEARL
MAMLEREGRLNRAIEFLPDDAEIERRRAGGQGLTSPERAVLMAYSKMWLSDLLLASDLLE
APFVARDLPLYFPQPLRSRFAQAMTRHPLQREILATMLANALVNRAGVTFVHRMTEETGA
EPAQVVRASLIARAVFRLDDVWQAIDALDDRVGHEAQAAMFADTSLLLERATLWFLHHQA
GGAQASRAIEDFGAAVADLAPALDGLLVEDEAQALAQRQSALVEGGVPDALALQLASTEA
LVATLDIAEVAAACGRSLRVSASVYFALDQLLGYAWLHDGIASLPARTHWQMLARAALFE
TLAQVKRGLTRSVLRLSPQGDDALVLIEAWRSQREEPLARYRRLAADQHAAGPADLAMLS
VTLKALGEIETFEPPLNSP

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory