SitesBLAST
Comparing WP_048082853.1 NCBI__GCF_000745485.1:WP_048082853.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
5exeA Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-tpp adduct (see paper)
39% identity, 97% coverage: 4:376/383 of query aligns to 6:390/394 of 5exeA
5exdD Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-di-oxido-methyl-tpp (coom-tpp) intermediate (see paper)
39% identity, 97% coverage: 4:376/383 of query aligns to 6:390/394 of 5exdD
- active site: R30 (≠ T28), E58 (= E56), R108 (= R106)
- binding [2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-[1,1,2-tris(oxidanyl)-2-oxidanylidene-ethyl]-1,3-thiazol-3-ium-5-yl]ethoxy-oxidanyl-phosphoryl] hydrogen phosphate: Y27 (= Y25), P28 (= P26), I29 (= I27), R30 (≠ T28), E58 (= E56), R108 (= R106), D115 (≠ S113)
5c4iA Structure of an oxalate oxidoreductase (see paper)
39% identity, 97% coverage: 4:376/383 of query aligns to 6:390/394 of 5c4iA
6ciqA Pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with coenzyme a bound (see paper)
29% identity, 91% coverage: 2:350/383 of query aligns to 3:358/1169 of 6ciqA
Sites not aligning to the query:
- active site: 999
- binding coenzyme a: 423, 424, 427, 428, 553, 586, 999
- binding magnesium ion: 966, 994, 996
- binding iron/sulfur cluster: 678, 680, 685, 686, 688, 689, 691, 695, 696, 700, 734, 741, 742, 743, 744, 745, 747, 751, 757, 807, 808, 811, 813, 836, 998, 1074, 1075
- binding thiamine diphosphate: 813, 835, 836, 865, 965, 966, 967, 996, 997, 998, 999, 1000
6cinB Crystal structure of pyruvate:ferredoxin oxidoreductase from moorella thermoacetica (see paper)
29% identity, 91% coverage: 2:350/383 of query aligns to 3:358/1169 of 6cinB
Sites not aligning to the query:
- active site: 999
- binding magnesium ion: 966, 994, 996
- binding iron/sulfur cluster: 455, 678, 685, 686, 687, 688, 689, 691, 695, 700, 741, 742, 743, 744, 745, 746, 747, 751, 752, 757, 758, 807, 808, 811, 813, 836, 998, 1074, 1075
- binding thiamine diphosphate: 834, 835, 836, 865, 965, 966, 967, 996, 997, 998, 999, 1000
Q2RMD6 Pyruvate:ferredoxin oxidoreductase; PFOR; Pyruvate synthase; EC 1.2.7.1 from Moorella thermoacetica (strain ATCC 39073 / JCM 9320) (see paper)
29% identity, 91% coverage: 2:350/383 of query aligns to 4:359/1171 of Q2RMD6
Sites not aligning to the query:
- 424:428 binding CoA
- 456 binding CoA
- 556 binding CoA
- 598 binding CoA
- 686 binding [4Fe-4S] cluster
- 689 binding [4Fe-4S] cluster
- 692 binding [4Fe-4S] cluster
- 696 binding [4Fe-4S] cluster
- 742 binding [4Fe-4S] cluster
- 745 binding [4Fe-4S] cluster
- 748 binding [4Fe-4S] cluster
- 752 binding [4Fe-4S] cluster
- 809 binding [4Fe-4S] cluster
- 812 binding [4Fe-4S] cluster
- 814 binding thiamine diphosphate
- 837 binding [4Fe-4S] cluster; binding thiamine diphosphate
- 967 binding Mg(2+)
- 967:969 binding thiamine diphosphate
- 995 binding Mg(2+)
- 995:1000 binding thiamine diphosphate
- 997 binding Mg(2+)
- 1075 binding [4Fe-4S] cluster
6cioA Pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with lactyl-tpp bound (see paper)
29% identity, 91% coverage: 2:350/383 of query aligns to 3:358/1164 of 6cioA
Sites not aligning to the query:
- active site: 999
- binding magnesium ion: 966, 994, 996
- binding iron/sulfur cluster: 455, 678, 680, 685, 686, 688, 689, 691, 695, 699, 700, 734, 741, 742, 744, 745, 747, 751, 757, 758, 807, 808, 811, 813, 836, 1074, 1075
- binding 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-(1-carboxy-1-hydroxyethyl)-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium: 813, 834, 835, 836, 865, 965, 966, 967, 996, 997, 998, 999, 1000
6cipA Pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with acetyl-tpp bound (see paper)
29% identity, 91% coverage: 2:350/383 of query aligns to 3:358/1165 of 6cipA
Sites not aligning to the query:
- active site: 999
- binding 2-acetyl-thiamine diphosphate: 813, 834, 835, 836, 865, 965, 966, 967, 996, 998, 999
- binding magnesium ion: 966, 994, 996
- binding iron/sulfur cluster: 455, 678, 680, 685, 686, 688, 689, 691, 695, 699, 700, 734, 741, 742, 744, 745, 747, 751, 757, 758, 807, 808, 811, 813, 836, 998, 1074
7plmA Cryoem reconstruction of pyruvate ferredoxin oxidoreductase (pfor) in anaerobic conditions (see paper)
30% identity, 85% coverage: 1:326/383 of query aligns to 4:336/1177 of 7plmA
Sites not aligning to the query:
- binding calcium ion: 950, 952, 1026, 1028
- binding magnesium ion: 930, 958, 960, 962
- binding iron/sulfur cluster: 458, 657, 659, 664, 665, 666, 667, 668, 670, 674, 675, 679, 708, 715, 716, 717, 718, 719, 721, 725, 726, 731, 732, 781, 782, 785, 787, 810, 962, 1038, 1039
- binding thiamine diphosphate: 787, 808, 809, 810, 839, 929, 930, 931, 960, 961, 962, 963, 964
2c3uA Crystal structure of pyruvate-ferredoxin oxidoreductase from desulfovibrio africanus, oxygen inhibited form (see paper)
30% identity, 85% coverage: 1:326/383 of query aligns to 4:336/1231 of 2c3uA
Sites not aligning to the query:
- active site: 995
- binding 2-(3-{[4-(hydroxyamino)-2-methylpyrimidin-5-yl]methyl}-4-methyl-2,3-dihydro-1,3-thiazol-5-yl)ethyl trihydrogen diphosphate: 816, 837, 839, 868, 869, 961, 962, 963, 964, 992, 993, 994, 995, 996
- binding calcium ion: 982, 984, 1055, 1056, 1058, 1060, 1062
- binding magnesium ion: 962, 990, 992
- binding pyruvic acid: 995
- binding iron/sulfur cluster: 458, 681, 683, 688, 689, 691, 692, 694, 698, 699, 702, 703, 744, 745, 746, 747, 748, 750, 754, 755, 760, 761, 811, 814, 816, 839, 1070, 1071
2c3pA Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase from desulfovibrio africanus (see paper)
30% identity, 85% coverage: 1:326/383 of query aligns to 4:336/1231 of 2c3pA
- active site: T30 (= T28), E63 (= E56), R113 (= R106)
- binding 1-(2-{(2s,4r,5r)-3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-[(1s)-1-carboxy-1-hydroxyethyl]-4-methyl-1,3-thiazolidin-5-yl}ethoxy)-1,1,3,3-tetrahydroxy-1lambda~5~-diphosphox-1-en-2-ium 3-oxide: P28 (= P26), I29 (= I27), T30 (= T28), E63 (= E56), Q87 (= Q80), R113 (= R106)
Sites not aligning to the query:
- active site: 995
- binding 1-(2-{(2s,4r,5r)-3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-[(1s)-1-carboxy-1-hydroxyethyl]-4-methyl-1,3-thiazolidin-5-yl}ethoxy)-1,1,3,3-tetrahydroxy-1lambda~5~-diphosphox-1-en-2-ium 3-oxide: 816, 837, 838, 839, 868, 869, 961, 962, 963, 992, 993, 994, 995, 996
- binding calcium ion: 982, 983, 984, 1055, 1056, 1058, 1060, 1062
- binding magnesium ion: 962, 990, 992
- binding iron/sulfur cluster: 458, 681, 683, 688, 689, 690, 691, 692, 694, 698, 699, 702, 703, 744, 745, 746, 747, 748, 750, 754, 755, 760, 761, 810, 811, 814, 816, 839, 994, 1070, 1071
2c3oA Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase from desulfovibrio africanus (see paper)
30% identity, 85% coverage: 1:326/383 of query aligns to 4:336/1231 of 2c3oA
Sites not aligning to the query:
- active site: 995
- binding calcium ion: 982, 984, 1056, 1058, 1060
- binding magnesium ion: 962, 990, 992
- binding pyruvic acid: 996
- binding iron/sulfur cluster: 458, 681, 688, 689, 691, 692, 694, 698, 699, 702, 703, 744, 746, 747, 748, 749, 750, 754, 760, 761, 810, 811, 814, 816, 839, 1070, 1071
- binding thiamine diphosphate: 816, 837, 838, 839, 868, 961, 962, 963, 992, 993, 994, 995, 996
1kekA Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase (see paper)
30% identity, 85% coverage: 1:326/383 of query aligns to 4:336/1231 of 1kekA