Comparing WP_050654573.1 NCBI__GCF_002893965.1:WP_050654573.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
2xuaH Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
40% identity, 62% coverage: 5:246/393 of query aligns to 15:253/261 of 2xuaH
6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
32% identity, 61% coverage: 3:242/393 of query aligns to 9:244/268 of 6eb3B
6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
31% identity, 61% coverage: 3:242/393 of query aligns to 9:241/265 of 6eb3A
6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
31% identity, 61% coverage: 3:242/393 of query aligns to 9:238/262 of 6eb3C
4uhfA Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
31% identity, 62% coverage: 2:246/393 of query aligns to 14:261/278 of 4uhfA
4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound) (see paper)
31% identity, 62% coverage: 2:246/393 of query aligns to 14:261/272 of 4uheA
4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound) (see paper)
31% identity, 62% coverage: 2:246/393 of query aligns to 14:261/274 of 4uhdA
3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase (see paper)
31% identity, 56% coverage: 27:248/393 of query aligns to 31:265/271 of 3hi4A
Sites not aligning to the query:
3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog (see paper)
31% identity, 56% coverage: 27:248/393 of query aligns to 31:265/271 of 3ia2A
Sites not aligning to the query:
P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 5 papers)
31% identity, 56% coverage: 27:248/393 of query aligns to 32:266/272 of P22862
Sites not aligning to the query:
3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase (see paper)
31% identity, 56% coverage: 27:248/393 of query aligns to 31:265/271 of 3heaA
Sites not aligning to the query:
8pi1B Bicyclic incypro pseudomonas fluorescens esterase (see paper)
31% identity, 56% coverage: 27:248/393 of query aligns to 31:265/276 of 8pi1B
Sites not aligning to the query:
5h3hB Esterase (eaest) from exiguobacterium antarcticum (see paper)
26% identity, 60% coverage: 18:254/393 of query aligns to 24:268/269 of 5h3hB
7c4dA Marine microorganism esterase (see paper)
33% identity, 31% coverage: 2:122/393 of query aligns to 1:115/261 of 7c4dA
Sites not aligning to the query:
5yb5B The complex crystal structure of vreh2 mutant m263n with sno
34% identity, 31% coverage: 14:133/393 of query aligns to 23:143/318 of 5yb5B
Sites not aligning to the query:
5am2A Ligand complex structure of soluble epoxide hydrolase (see paper)
27% identity, 45% coverage: 3:178/393 of query aligns to 242:413/537 of 5am2A
Sites not aligning to the query:
5am5A Ligand complex structure of soluble epoxide hydrolase (see paper)
30% identity, 34% coverage: 3:136/393 of query aligns to 247:379/546 of 5am5A
Sites not aligning to the query:
5am4A Ligand complex structure of soluble epoxide hydrolase (see paper)
30% identity, 34% coverage: 3:136/393 of query aligns to 247:379/546 of 5am4A
Sites not aligning to the query:
5am1A Ligand complex structure of soluble epoxide hydrolase (see paper)
30% identity, 34% coverage: 3:136/393 of query aligns to 247:379/546 of 5am1A
Sites not aligning to the query:
5am0A Ligand complex structure of soluble epoxide hydrolase (see paper)
30% identity, 34% coverage: 3:136/393 of query aligns to 247:379/546 of 5am0A
Sites not aligning to the query:
>WP_050654573.1 NCBI__GCF_002893965.1:WP_050654573.1
MSVALNFQQTGNLDAPAVVLLGSLGSDLSMWQPQIHALSNRYRVIAVDHRGHGKSPVPAG
PYSIADLAGDVIALLDSLELESVHLVGLSLGGAVSQWIAAHHPTRVETLTLMCTSAQFAP
AQPWIDRAQAVRADGIASIAAAVVGRWFTPGLADNDPELVARHVAMVEATPDEGYAACCE
ALSVWDGRADLARIVAPTLLIAGEQDPATPPATLSAIADGIADAVLHVVDPGAHLANVEQ
AGRVTKLLATHIASHTSTLAQRSAAVSAGMTVRRQVLGDAHVDRSIAGATEFTAPFQDFI
TRTAWGDIWSRPGLDHHTRRLLTLAILTAVGNEHELDMHIRAALRAGIDPDELVEVFLHT
AVYAGVPNSNLAFALGKQALADLSAEPEENETT
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory