Comparing WP_050654880.1 NCBI__GCF_002893965.1:WP_050654880.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 3 papers)
27% identity, 84% coverage: 14:232/261 of query aligns to 303:509/520 of Q29551
Sites not aligning to the query:
3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart. (see paper)
27% identity, 84% coverage: 14:232/261 of query aligns to 250:456/466 of 3k6mC
Sites not aligning to the query:
1o9lA Succinate:coenzyme-a transferase (pig heart)
27% identity, 84% coverage: 14:232/261 of query aligns to 251:457/468 of 1o9lA
Sites not aligning to the query:
3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa (see paper)
27% identity, 85% coverage: 12:232/261 of query aligns to 244:452/462 of 3oxoE
5mzzB Crystal structure of the decarboxylase aiba/aibb in complex with 3- methylglutaconate (see paper)
23% identity, 93% coverage: 9:250/261 of query aligns to 1:227/241 of 5mzzB
5mzxB Crystal structure of the decarboxylase aiba/aibb in complex with 4'- diphospho pantetheine (see paper)
23% identity, 93% coverage: 9:250/261 of query aligns to 1:227/241 of 5mzxB
5mzyB Crystal structure of the decarboxylase aiba/aibb in complex with a possible transition state analog (see paper)
23% identity, 93% coverage: 9:250/261 of query aligns to 4:230/244 of 5mzyB
Q0S7Q0 Cholesterol ring-cleaving hydrolase IpdB subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit; COCHEA-CoA hydrolase beta subunit; EC 4.1.99.- from Rhodococcus jostii (strain RHA1) (see paper)
27% identity, 95% coverage: 13:261/261 of query aligns to 2:249/253 of Q0S7Q0
6cojB Crystal structure of rhodococcus jostii rha1 ipdab e105a cochea-coa complex (see paper)
27% identity, 89% coverage: 30:261/261 of query aligns to 16:244/248 of 6cojB
8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
25% identity, 88% coverage: 11:240/261 of query aligns to 245:458/459 of 8i3yA
Sites not aligning to the query:
8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
23% identity, 87% coverage: 14:241/261 of query aligns to 254:467/467 of 8i40A
8i3yD Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
23% identity, 87% coverage: 14:241/261 of query aligns to 258:471/471 of 8i3yD
Sites not aligning to the query:
>WP_050654880.1 NCBI__GCF_002893965.1:WP_050654880.1
MTTTIVSGNTTSTETIVAVAARELAGKRRVFAGVGLPTLAVDLARHTSNPDVELIYESGV
CGAHPSAMAEGIADSVVVSGAESVLSMAALFGYVLQGGNVDVGFLGAAQIDRTGSLNTSF
IGDWKNPTVRLPGAGGAVEIIANAAEIFVVMRRHDLSSFPAALDFCTSPSPARAHASGKG
IMPAGAGVTKVFTNLGVLTHQGPGGELELTSVHEGISVHQVREATGWDLAVADHVTVTTP
PSGTEIDLLRNTIDKVRLYLR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory