SitesBLAST
Comparing WP_050655857.1 NCBI__GCF_002893965.1:WP_050655857.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3nf4A Crystal structure of acyl-coa dehydrogenase from mycobacterium thermoresistibile bound to flavin adenine dinucleotide (see paper)
76% identity, 99% coverage: 1:378/380 of query aligns to 1:368/369 of 3nf4A
- active site: L127 (= L127), S128 (= S128), G240 (= G243), E354 (= E364), R366 (= R376)
- binding flavin-adenine dinucleotide: Y125 (= Y125), L127 (= L127), S128 (= S128), G133 (= G133), S134 (= S134), W158 (= W158), T160 (= T160), I349 (= I359), T356 (= T366), Q358 (= Q368), I359 (= I369)
4n5fA Crystal structure of a putative acyl-coa dehydrogenase with bound fadh2 from burkholderia cenocepacia j2315
45% identity, 97% coverage: 9:378/380 of query aligns to 7:378/378 of 4n5fA
- active site: L126 (= L127), T127 (≠ S128), G243 (= G243), E364 (= E364), R376 (= R376)
- binding dihydroflavine-adenine dinucleotide: L126 (= L127), T127 (≠ S128), G132 (= G133), S133 (= S134), F157 (≠ W158), T159 (= T160), T210 (= T210), Y363 (≠ F363), T366 (= T366), E368 (≠ Q368), M372 (≠ L372)
2dvlA Crystal structure of project tt0160 from thermus thermophilus hb8
49% identity, 97% coverage: 9:378/380 of query aligns to 2:368/370 of 2dvlA
- active site: L121 (= L127), T122 (≠ S128), G233 (= G243), E354 (= E364), R366 (= R376)
- binding flavin-adenine dinucleotide: L121 (= L127), T122 (≠ S128), G127 (= G133), S128 (= S134), W152 (= W158), I153 (= I159), T154 (= T160), T356 (= T366), E358 (≠ Q368)
5lnxD Crystal structure of mmgc, an acyl-coa dehydrogenase from bacillus subtilis.
44% identity, 98% coverage: 7:380/380 of query aligns to 1:374/374 of 5lnxD
- active site: L122 (= L127), T123 (≠ S128), G239 (= G243), E358 (= E364), K370 (≠ R376)
- binding flavin-adenine dinucleotide: L122 (= L127), T123 (≠ S128), G128 (= G133), S129 (= S134), F153 (≠ W158), T155 (= T160), R265 (= R269), Q267 (≠ A271), F268 (= F272), I272 (= I276), N275 (≠ H279), I278 (≠ L282), Q331 (= Q337), I332 (≠ V338), G335 (= G341), Y357 (≠ F363), T360 (= T366), E362 (≠ Q368)
4l1fA Electron transferring flavoprotein of acidaminococcus fermentans: towards a mechanism of flavin-based electron bifurcation (see paper)
43% identity, 97% coverage: 9:378/380 of query aligns to 6:377/380 of 4l1fA
- active site: L125 (= L127), T126 (≠ S128), G242 (= G243), E363 (= E364), R375 (= R376)
- binding coenzyme a persulfide: T132 (≠ S134), H179 (≠ R180), F232 (≠ L233), M236 (≠ F237), E237 (≠ S238), L239 (= L240), D240 (= D241), R243 (= R244), Y362 (≠ F363), E363 (= E364), G364 (= G365), R375 (= R376)
- binding flavin-adenine dinucleotide: F123 (≠ Y125), L125 (= L127), T126 (≠ S128), G131 (= G133), T132 (≠ S134), F156 (≠ W158), I157 (= I159), T158 (= T160), R268 (= R269), Q270 (≠ A271), F271 (= F272), I275 (= I276), F278 (≠ H279), L281 (= L282), Q336 (= Q337), I337 (≠ V338), G340 (= G341), I358 (= I359), Y362 (≠ F363), T365 (= T366), Q367 (= Q368)
- binding 1,3-propandiol: Q10 (≠ R13)
Sites not aligning to the query:
4m9aB Crystal structure of acyl-coa dehydrogenase from burkholderia thailandensis e264
45% identity, 97% coverage: 9:378/380 of query aligns to 5:376/376 of 4m9aB
- active site: L124 (= L127), T125 (≠ S128), G241 (= G243), E362 (= E364), R374 (= R376)
- binding dihydroflavine-adenine dinucleotide: F122 (≠ Y125), T125 (≠ S128), G130 (= G133), S131 (= S134), F155 (≠ W158), T157 (= T160), T208 (= T210), Y361 (≠ F363), T364 (= T366), E366 (≠ Q368), M370 (≠ L372)
7w0jE Acyl-coa dehydrogenase, tfu_1647
44% identity, 98% coverage: 8:378/380 of query aligns to 7:380/382 of 7w0jE
- binding [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4S)-5-azanyl-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate: S127 (= S128), W157 (= W158), R270 (= R269), Q272 (≠ A271), F273 (= F272), I277 (= I276), F280 (≠ H279), I283 (≠ L282), Q339 (= Q337), L340 (≠ V338), G343 (= G341), Y365 (≠ F363), E366 (= E364), T368 (= T366), Q370 (= Q368), I371 (= I369)
8i4rA Crystal structure of acyl-coa dehydrogenase complexed with acetyl-coa from thermobifida fusca
44% identity, 98% coverage: 8:378/380 of query aligns to 6:379/381 of 8i4rA
- binding acetyl coenzyme *a: S132 (= S134), T134 (≠ A136), R180 (vs. gap), R234 (≠ P234), L237 (≠ F237), R238 (≠ S238), L240 (= L240), D241 (= D241), R244 (= R244), E365 (= E364), G366 (= G365), R377 (= R376)
- binding flavin-adenine dinucleotide: Y123 (= Y125), L125 (= L127), S126 (= S128), G131 (= G133), S132 (= S134), W156 (= W158), I157 (= I159), T158 (= T160), I360 (= I359), T367 (= T366), Q369 (= Q368)
8i4pA Crystal structure of acyl-coa dehydrogenase from thermobifida fusca
44% identity, 98% coverage: 8:378/380 of query aligns to 6:379/381 of 8i4pA
- binding flavin-adenine dinucleotide: Y123 (= Y125), L125 (= L127), S126 (= S128), G131 (= G133), S132 (= S134), W156 (= W158), I157 (= I159), T158 (= T160), I360 (= I359), Y364 (≠ F363), T367 (= T366), Q369 (= Q368)
3pfdC Crystal structure of an acyl-coa dehydrogenase from mycobacterium thermoresistibile bound to reduced flavin adenine dinucleotide solved by combined iodide ion sad mr (see paper)
44% identity, 96% coverage: 15:378/380 of query aligns to 4:367/369 of 3pfdC
- active site: L116 (= L127), S117 (= S128), T233 (≠ G243), E353 (= E364), R365 (= R376)
- binding dihydroflavine-adenine dinucleotide: Y114 (= Y125), L116 (= L127), S117 (= S128), G122 (= G133), S123 (= S134), W147 (= W158), I148 (= I159), T149 (= T160), R259 (= R269), F262 (= F272), V266 (≠ I276), N269 (≠ H279), Q326 (= Q337), L327 (≠ V338), G330 (= G341), I348 (= I359), Y352 (≠ F363), T355 (= T366), Q357 (= Q368)
5ol2F The electron transferring flavoprotein/butyryl-coa dehydrogenase complex from clostridium difficile (see paper)
42% identity, 98% coverage: 7:378/380 of query aligns to 3:376/378 of 5ol2F
- active site: L124 (= L127), T125 (≠ S128), G241 (= G243), G374 (≠ R376)
- binding calcium ion: E29 (= E33), E33 (≠ A37), R35 (≠ K39)
- binding coenzyme a persulfide: L238 (= L240), R242 (= R244), E362 (= E364), G363 (= G365)
- binding flavin-adenine dinucleotide: F122 (≠ Y125), L124 (= L127), T125 (≠ S128), P127 (≠ A130), T131 (≠ S134), F155 (≠ W158), I156 (= I159), T157 (= T160), E198 (= E200), R267 (= R269), F270 (= F272), L274 (≠ I276), F277 (≠ H279), Q335 (= Q337), L336 (≠ V338), G338 (= G340), G339 (= G341), Y361 (≠ F363), T364 (= T366), E366 (≠ Q368)
P15651 Short-chain specific acyl-CoA dehydrogenase, mitochondrial; SCAD; Butyryl-CoA dehydrogenase; EC 1.3.8.1 from Rattus norvegicus (Rat) (see 2 papers)
42% identity, 96% coverage: 15:378/380 of query aligns to 41:406/412 of P15651