SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_052296910.1 NCBI__GCF_000223395.1:WP_052296910.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

3al0C Crystal structure of the glutamine transamidosome from thermotoga maritima in the glutamylation state. (see paper)
29% identity, 95% coverage: 3:90/93 of query aligns to 4:92/564 of 3al0C

query
sites
3al0C

R

K

E

D

L

L

V

V

K

L

R

H

L

L

E

E

E

N

M

L

V

A

R

R

I

L

S

E

L

L

T

S

P

E

E

D

E

Q

E

R

E

E

R

S

M

L

I

M

S

K

E

D

L

F

S

Q

K

E

I

I

L

L

E

D

W

Y

M

V

R

E

V

L

L

L

L

N

D

E

A

V

K

D

V

V

V

E

G

G

-

V

D

E

P

P

L

M

Y

Y

H

T

P

P

S

V

D

E

V

D

E

S

G

A

L

K

L

L

R

R

R

K

D

G

D

D

P

P

K

R

P

F

S

F

L

E

P

M

R

R

E

D

E

L

A

I

L

K

R

K

N

N

A

F

V

P

E

E

V

E

I

K

D

D

G

G

F

H

V

I

K

K

A

V

P

P

K

G

L

I

Sites not aligning to the query:

active site: 110, 335
binding o5'-(l-glutamyl-sulfamoyl)-adenosine: 106, 108, 109, 118, 122, 142, 276, 294, 295, 297, 298, 324, 325, 333
binding : 144, 145, 148, 208, 213, 252, 255, 266, 269, 270, 276, 297, 298, 299, 300, 301, 304, 330, 332, 363, 364, 365, 370, 387, 389, 391, 392, 397, 400, 407, 446, 447, 453, 457, 509, 520, 524, 527, 535, 536, 538, 539

Query Sequence

>WP_052296910.1 NCBI__GCF_000223395.1:WP_052296910.1
MDRELVKRLEEMVRISLTPEEEERMISELSKILEWMRVLLDAKVVGDPLYHPSDVEGLLR
RDDPKPSLPREEALRNAVEVIDGFVKAPKLVEE

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory