SitesBLAST
Comparing WP_053938289.1 NCBI__GCF_001294205.1:WP_053938289.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4ebuA Crystal structure of a sugar kinase (target efi-502312) from oceanicola granulosus, with bound amp/adp crystal form i
41% identity, 96% coverage: 4:302/312 of query aligns to 15:304/306 of 4ebuA
- active site: A263 (= A261), A264 (= A262), G265 (= G263), D266 (= D264)
- binding adenosine-5'-diphosphate: S202 (≠ T198), K233 (≠ Q231), G235 (= G233), V255 (= V253), A264 (= A262), G265 (= G263), F268 (= F266), A293 (= A291)
4eumA Crystal structure of a sugar kinase (target efi-502132) from oceanicola granulosus with bound amp, crystal form ii
41% identity, 94% coverage: 4:296/312 of query aligns to 15:294/294 of 4eumA
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
34% identity, 95% coverage: 4:299/312 of query aligns to 2:286/300 of 1v1bA
- active site: G248 (≠ A261), A249 (= A262), G250 (= G263), D251 (= D264)
- binding adenosine-5'-triphosphate: K219 (= K230), G221 (= G232), A238 (= A251), F239 (≠ P252), V241 (≠ A254), G248 (≠ A261), A249 (= A262), G250 (= G263), N275 (= N288), A279 (≠ G292)
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
34% identity, 95% coverage: 4:299/312 of query aligns to 2:286/309 of Q53W83
- GAEVN 34:38 (≠ GDTLN 30:34) binding substrate
- YYR 103:105 (≠ YWR 104:106) binding substrate
- R167 (= R171) binding substrate
- S193 (≠ D200) binding ATP
- 219:225 (vs. 230:236, 29% identical) binding ATP
- GAGD 248:251 (≠ AAGD 261:264) binding ATP
- D251 (= D264) binding substrate
- N275 (= N288) binding ATP
Sites not aligning to the query:
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
34% identity, 95% coverage: 4:299/312 of query aligns to 2:286/301 of 1v1aA
- active site: G248 (≠ A261), A249 (= A262), G250 (= G263), D251 (= D264)
- binding adenosine-5'-diphosphate: K219 (= K230), G221 (= G232), A222 (≠ G233), A249 (= A262), G250 (= G263), N275 (= N288), A279 (≠ G292)
- binding 2-keto-3-deoxygluconate: L11 (≠ M13), G34 (= G30), A35 (≠ D31), N38 (= N34), Y89 (= Y90), R105 (= R106), R167 (= R171), G248 (≠ A261), D251 (= D264)
Sites not aligning to the query:
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
26% identity, 86% coverage: 5:271/312 of query aligns to 6:259/319 of Q8ZKR2
- D16 (≠ E15) binding 5-amino-1-(beta-D-ribosyl)imidazole
- G31 (= G30) binding 5-amino-1-(beta-D-ribosyl)imidazole
- Y101 (= Y104) binding 5-amino-1-(beta-D-ribosyl)imidazole
- R162 (= R171) binding 5-amino-1-(beta-D-ribosyl)imidazole
- A180 (≠ F189) binding K(+)
- A181 (= A190) binding K(+)
- A183 (≠ S192) binding K(+)
- G213 (≠ P223) binding K(+)
- D246 (= D258) binding K(+)
- T248 (= T260) binding K(+)
- D252 (= D264) binding 5-amino-1-(beta-D-ribosyl)imidazole
Sites not aligning to the query:
- 287 binding K(+)
- 290 binding K(+)
- 292 binding K(+)
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
27% identity, 87% coverage: 5:276/312 of query aligns to 3:260/306 of 5eynA
- active site: G246 (≠ A261), A247 (= A262), G248 (= G263), D249 (= D264)
- binding adenosine-5'-diphosphate: H91 (= H97), T217 (≠ K230), G219 (= G232), A220 (≠ G233), A238 (≠ V253), V239 (≠ A254), T244 (= T259), G246 (≠ A261), A247 (= A262), G248 (= G263), F251 (= F266)
- binding beryllium trifluoride ion: G246 (≠ A261), G248 (= G263), D249 (= D264)
- binding beta-D-fructofuranose: D9 (≠ E11), D13 (≠ E15), G28 (= G30), A29 (≠ D31), N32 (= N34), F96 (= F102), F98 (≠ Y104), R159 (= R171), D249 (= D264)
Sites not aligning to the query:
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
26% identity, 86% coverage: 5:271/312 of query aligns to 2:248/297 of 1tz6A
- active site: C24 (≠ S27), F88 (= F102), G238 (≠ A261), A239 (= A262), G240 (= G263), D241 (= D264)
- binding phosphomethylphosphonic acid adenylate ester: N149 (= N169), K176 (≠ L196), E181 (≠ D201), S209 (≠ K230), G211 (= G233), A212 (= A234), G214 (≠ T236), A239 (= A262), G240 (= G263), F243 (= F266)
- binding 5-aminoimidazole ribonucleoside: D8 (≠ E11), D12 (≠ E15), G27 (= G30), F88 (= F102), Y90 (= Y104), R151 (= R171), M154 (≠ L174), D241 (= D264)
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
26% identity, 86% coverage: 5:271/312 of query aligns to 2:248/299 of 1tz3A
- active site: C24 (≠ S27), F88 (= F102), G238 (≠ A261), A239 (= A262), G240 (= G263), D241 (= D264)
- binding 5-aminoimidazole ribonucleoside: D8 (≠ E11), S10 (≠ M13), D12 (≠ E15), G27 (= G30), L83 (= L91), F88 (= F102), Y90 (= Y104), R151 (= R171), M154 (≠ L174), D241 (= D264)
3in1A Crystal structure of a putative ribokinase in complex with adp from e.Coli
25% identity, 87% coverage: 29:300/312 of query aligns to 39:294/312 of 3in1A
- active site: R106 (= R100), G255 (≠ A261), A256 (= A262), G257 (= G263), D258 (= D264)
- binding adenosine-5'-diphosphate: N194 (= N193), K225 (= K230), G227 (= G232), G230 (≠ D235), A244 (≠ P250), T253 (= T259), N282 (= N288), A285 (= A291)
7fcaD Pfkb(mycobacterium marinum) (see paper)
29% identity, 85% coverage: 8:271/312 of query aligns to 6:237/282 of 7fcaD
2varA Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
25% identity, 94% coverage: 6:299/312 of query aligns to 3:292/311 of 2varA
- active site: G254 (≠ A261), A255 (= A262), G256 (= G263), D257 (= D264)
- binding adenosine monophosphate: G227 (= G232), G230 (≠ D235), M259 (≠ F266), S284 (≠ A291), I288 (= I295)
- binding phosphoaminophosphonic acid-adenylate ester: K225 (= K230), G227 (= G232), S228 (≠ G233), G230 (≠ D235), G254 (≠ A261), A255 (= A262), G256 (= G263), D257 (= D264), M259 (≠ F266), I281 (≠ N288), S284 (≠ A291), I288 (= I295)
- binding 3-deoxy-alpha-D-erythro-hex-2-ulofuranosonic acid: L10 (≠ M13), G33 (= G30), S34 (≠ D31), Y89 (= Y90), Y105 (= Y104), R107 (= R106), I136 (= I137), R165 (= R171), G254 (≠ A261), D257 (= D264)
- binding 2-keto-3-deoxygluconate: G33 (= G30), S34 (≠ D31), Y89 (= Y90), L103 (≠ F102), Y105 (= Y104), R107 (= R106), I136 (= I137), R165 (= R171), T253 (= T260), G254 (≠ A261), D257 (= D264)
Sites not aligning to the query:
Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
25% identity, 94% coverage: 6:299/312 of query aligns to 4:293/313 of Q97U29
Sites not aligning to the query:
3lkiB Crystal structure of fructokinase with bound atp from xylella fastidiosa
26% identity, 85% coverage: 6:271/312 of query aligns to 5:260/322 of 3lkiB
Sites not aligning to the query:
4wjmA Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
26% identity, 86% coverage: 6:273/312 of query aligns to 8:264/312 of 4wjmA
- active site: G252 (≠ A261), A253 (= A262), G254 (= G263), D255 (= D264)
- binding phosphoaminophosphonic acid-adenylate ester: T223 (≠ Q231), G225 (= G233), A226 (= A234), G228 (≠ T236), G252 (≠ A261), A253 (= A262), G254 (= G263), V257 (≠ F266)
Sites not aligning to the query:
2dcnA Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
24% identity, 89% coverage: 5:283/312 of query aligns to 2:274/308 of 2dcnA