SitesBLAST
Comparing WP_054255670.1 NCBI__GCF_001298675.1:WP_054255670.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6x9dA Structure of proline utilization a with trans-4-hydroxy-l-proline bound in the l-glutamate-gamma-semialdehyde dehydrogenase active site (see paper)
60% identity, 94% coverage: 78:1334/1335 of query aligns to 4:1217/1218 of 6x9dA
- active site: N692 (= N788), K715 (= K811), E795 (= E892), C829 (= C926), E925 (= E1022), A1007 (= A1104)
- binding flavin-adenine dinucleotide: D291 (= D368), A292 (= A369), V323 (= V400), Q325 (= Q402), R352 (= R429), V354 (= V431), K355 (= K432), G356 (= G433), A357 (= A434), Y358 (= Y435), W359 (= W436), F377 (≠ Y454), T378 (= T455), R379 (= R456), K380 (= K457), T383 (= T460), A406 (= A483), T407 (= T484), H408 (= H485), N409 (= N486), Q432 (= Q512), C433 (= C513), E477 (= E560), S483 (= S566), F484 (= F567)
- binding 4-hydroxyproline: E659 (= E754), F693 (= F789), I697 (= I793), R828 (= R925), S830 (= S927), G987 (= G1084), A988 (= A1085), F995 (= F1092)
- binding nicotinamide-adenine-dinucleotide: I688 (= I784), S689 (= S785), P690 (= P786), W691 (= W787), N692 (= N788), I697 (= I793), K715 (= K811), A717 (= A813), E718 (= E814), G748 (= G844), G751 (= G848), A752 (= A849), T766 (= T863), G767 (= G864), S768 (= S865), V771 (= V868), E795 (= E892), T796 (= T893), C829 (= C926), E925 (= E1022), F927 (= F1024), F995 (= F1092)
7mybA Structure of proline utilization a with tetrahydrothiophene-2- carboxylate bound in the proline dehydrogenase active site (see paper)
60% identity, 94% coverage: 78:1334/1335 of query aligns to 4:1216/1217 of 7mybA
- binding flavin-adenine dinucleotide: D290 (= D368), A291 (= A369), V322 (= V400), Q324 (= Q402), R351 (= R429), V353 (= V431), K354 (= K432), G355 (= G433), A356 (= A434), Y357 (= Y435), W358 (= W436), F376 (≠ Y454), T377 (= T455), R378 (= R456), K379 (= K457), T382 (= T460), A405 (= A483), T406 (= T484), H407 (= H485), N408 (= N486), C432 (= C513), L433 (= L514), E476 (= E560), S482 (= S566), F483 (= F567)
- binding nicotinamide-adenine-dinucleotide: I687 (= I784), S688 (= S785), P689 (= P786), W690 (= W787), N691 (= N788), I696 (= I793), K714 (= K811), E717 (= E814), G747 (= G844), G750 (= G848), T765 (= T863), G766 (= G864), S767 (= S865), V770 (= V868), I774 (= I872), E794 (= E892), T795 (= T893), C828 (= C926), E924 (= E1022), F926 (= F1024), F994 (= F1092)
- binding (2S)-thiolane-2-carboxylic acid: K249 (= K327), Y457 (= Y541), Y469 (= Y553), R472 (= R556), R473 (= R557)
- binding (2R)-thiolane-2-carboxylic acid: K249 (= K327), D290 (= D368), Y457 (= Y541), Y469 (= Y553), R472 (= R556), R473 (= R557)
7myaA Structure of proline utilization a with the fad covalently-modified by 1,3-dithiolane (see paper)
60% identity, 94% coverage: 78:1334/1335 of query aligns to 4:1216/1217 of 7myaA
- binding nicotinamide-adenine-dinucleotide: I687 (= I784), S688 (= S785), P689 (= P786), W690 (= W787), N691 (= N788), I696 (= I793), K714 (= K811), A716 (= A813), E717 (= E814), G747 (= G844), G750 (= G848), A751 (= A849), T765 (= T863), G766 (= G864), S767 (= S865), V770 (= V868), E794 (= E892), T795 (= T893), C828 (= C926), E924 (= E1022), F926 (= F1024), F994 (= F1092)
- binding [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[5-(1,3-dithiolan-2-yl)-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate: D290 (= D368), A291 (= A369), V322 (= V400), Q324 (= Q402), V353 (= V431), K354 (= K432), G355 (= G433), A356 (= A434), W358 (= W436), F376 (≠ Y454), T377 (= T455), R378 (= R456), K379 (= K457), T382 (= T460), A405 (= A483), T406 (= T484), H407 (= H485), N408 (= N486), Q431 (= Q512), C432 (= C513), L433 (= L514), Y457 (= Y541), E476 (= E560)
Sites not aligning to the query:
- binding [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[5-(1,3-dithiolan-2-yl)-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate: 1217
7mycA Structure of proline utilization a with the fad covalently modified by tetrahydrothiophene (see paper)
60% identity, 94% coverage: 78:1334/1335 of query aligns to 4:1216/1216 of 7mycA