Comparing WP_057506907.1 NCBI__GCF_001431535.1:WP_057506907.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
3triA Structure of a pyrroline-5-carboxylate reductase (proc) from coxiella burnetii (see paper)
40% identity, 99% coverage: 4:273/273 of query aligns to 3:272/272 of 3triA
2ag8A NADP complex of pyrroline-5-carboxylate reductase from neisseria meningitidis (see paper)
40% identity, 97% coverage: 5:269/273 of query aligns to 2:259/263 of 2ag8A
5bshA Crystal structure of medicago truncatula (delta)1-pyrroline-5- carboxylate reductase (mtp5cr) in complex with l-proline (see paper)
36% identity, 97% coverage: 5:269/273 of query aligns to 10:272/272 of 5bshA
5bsgA Crystal structure of medicago truncatula (delta)1-pyrroline-5- carboxylate reductase (mtp5cr) in complex with NADP+ (see paper)
36% identity, 97% coverage: 5:269/273 of query aligns to 10:272/272 of 5bsgA
5bsfA Crystal structure of medicago truncatula (delta)1-pyrroline-5- carboxylate reductase (mtp5cr) in complex with NAD+ (see paper)
36% identity, 97% coverage: 5:269/273 of query aligns to 10:272/272 of 5bsfA
5bseA Crystal structure of medicago truncatula (delta)1-pyrroline-5- carboxylate reductase (mtp5cr) (see paper)
36% identity, 97% coverage: 5:269/273 of query aligns to 10:272/272 of 5bseA
6xp0A Structure of human pycr1 complexed with n-formyl l-proline (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 4:272/272 of 6xp0A
Q96C36 Pyrroline-5-carboxylate reductase 2; P5C reductase 2; P5CR 2; EC 1.5.1.2 from Homo sapiens (Human) (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 2:273/320 of Q96C36
Sites not aligning to the query:
6xp3A Structure of human pycr1 complexed with cyclopentanecarboxylic acid (see paper)
35% identity, 99% coverage: 5:273/273 of query aligns to 5:276/276 of 6xp3A
5uatC Structure of human pycr-1 complexed with NADPH (see paper)
35% identity, 99% coverage: 5:273/273 of query aligns to 6:277/277 of 5uatC
8td1A Structure of pycr1 complexed with 3-(6-oxa-9-azaspiro(4.5)decane-9- carbonyl)benzoic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 9:280/280 of 8td1A
8td0A Structure of pycr1 complexed with 5-oxo-7a-phenyl-hexahydropyrrolo[2, 1-b][1,3]thiazole-3-carboxylic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 9:280/280 of 8td0A
8tczA Structure of pycr1 complexed with 2-(pyridin-2-yl)cyclopropane-1- carboxylic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 9:280/280 of 8tczA
8tcxA Structure of pycr1 complexed with 2,4-dioxo-1,2,3,4- tetrahydroquinazoline-6-carboxylic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 9:280/280 of 8tcxA
8tcvB Structure of pycr1 complexed with 4-bromobenzene-1,3-dicarboxylic acid (see paper)
35% identity, 99% coverage: 5:273/273 of query aligns to 8:279/279 of 8tcvB
8tcyA Structure of pycr1 complexed with 7-fluoro-2-oxo-1,2,3,4- tetrahydroquinoline-6-carboxylic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 9:280/281 of 8tcyA
5uavA Structure of human pycr-1 complexed with NADPH and l-tetrahydrofuroic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 6:277/278 of 5uavA
2graA Crystal structure of human pyrroline-5-carboxylate reductase complexed with NADP (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 4:275/277 of 2graA
2gr9A Crystal structure of p5cr complexed with nadh (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 4:275/277 of 2gr9A
8tcwA Structure of pycr1 complexed with 2-methyl-3-(2-oxoimidazolidin-1-yl) benzoic acid (see paper)
34% identity, 99% coverage: 5:273/273 of query aligns to 9:280/282 of 8tcwA
>WP_057506907.1 NCBI__GCF_001431535.1:WP_057506907.1
MTDSSIAFIGGGNMARSLIAGLVRQGTPAADIHVAEPVAALRDALAADFGVSPHATASEA
AAQAGAWLLAVKPQVLREVCATLHALATAKRPLLVSIAAGITSAQLDRWLGGNIAVVRAM
PNTPALLGAGVTGLYATAQVTAAQRAQADRVLSSAGRTVWVDDEALMDSVTAVSGSGPAY
VFLLAEAMEAAGIAQGLPPEAARTLVQQTLLGASRMLDEAGEAPAELRRRVTSPGGTTHA
AIEAFQAGGFEPLVAKALAAAQARGRELSAAND
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory