Comparing WP_057508383.1 NCBI__GCF_001431535.1:WP_057508383.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6k1lB E53a mutant of a putative cystathionine gamma-lyase (see paper)
92% identity, 97% coverage: 11:392/392 of query aligns to 1:382/382 of 6k1lB
6k1lA E53a mutant of a putative cystathionine gamma-lyase (see paper)
92% identity, 97% coverage: 11:392/392 of query aligns to 1:382/382 of 6k1lA
4iyoB Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
89% identity, 97% coverage: 12:391/392 of query aligns to 1:380/381 of 4iyoB
4iy7B Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
89% identity, 97% coverage: 12:391/392 of query aligns to 1:380/381 of 4iy7B
4iy7A Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
89% identity, 97% coverage: 12:391/392 of query aligns to 1:380/381 of 4iy7A
4ixzA Native structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae at ph 9.0 (see paper)
89% identity, 97% coverage: 12:391/392 of query aligns to 1:380/381 of 4ixzA
4iyoD Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
89% identity, 97% coverage: 12:391/392 of query aligns to 1:380/384 of 4iyoD
4ixsB Native structure of xometc at ph 5.2 (see paper)
87% identity, 97% coverage: 13:391/392 of query aligns to 1:371/372 of 4ixsB
7ba4A Structure of cystathionine gamma-lyase from pseudomonas aeruginosa
65% identity, 97% coverage: 12:391/392 of query aligns to 4:371/377 of 7ba4A
6cjaA Crystal structure of cystathionine beta-lyase from legionella pneumophila philadelphia 1 in complex with alanyl-plp and serine
67% identity, 96% coverage: 17:391/392 of query aligns to 6:380/381 of 6cjaA
4l0oH Structure determination of cystathionine gamma-synthase from helicobacter pylori
55% identity, 97% coverage: 13:391/392 of query aligns to 1:370/373 of 4l0oH
8j6nA Crystal structure of cystathionine gamma-lyase in complex with compound 1 (see paper)
55% identity, 96% coverage: 15:392/392 of query aligns to 9:386/390 of 8j6nA
7d7oB Crystal structure of cystathionine gamma-lyase from bacillus cereus atcc 14579 (see paper)
54% identity, 96% coverage: 17:391/392 of query aligns to 5:376/377 of 7d7oB
3cogD Crystal structure of human cystathionase (cystathionine gamma lyase) in complex with dl-propargylglycine (see paper)
55% identity, 92% coverage: 15:376/392 of query aligns to 9:370/392 of 3cogD
6nbaA Crystal structure of human cystathionine gamma lyase with s-3- carboxpropyl-l-cysteine (see paper)
55% identity, 92% coverage: 15:376/392 of query aligns to 9:370/389 of 6nbaA
P32929 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Homo sapiens (Human) (see 5 papers)
55% identity, 92% coverage: 15:376/392 of query aligns to 18:379/405 of P32929
Sites not aligning to the query:
5eigC Engineered human cystathionine gamma lyase (e59t, e339v) to deplet cysteine
55% identity, 92% coverage: 15:376/392 of query aligns to 9:368/388 of 5eigC
6ldoA Crystal structure of cystathionine gamma-lyase from lactobacillus plantarum complexed with l-serine (see paper)
51% identity, 97% coverage: 13:391/392 of query aligns to 1:375/381 of 6ldoA
6le4A Crystal structure of cystathionine gamma-lyase from lactobacillus plantarum complexed with cystathionine (see paper)
51% identity, 97% coverage: 13:391/392 of query aligns to 1:375/380 of 6le4A
7mcyH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl3 (see paper)
50% identity, 96% coverage: 17:392/392 of query aligns to 5:378/380 of 7mcyH
Sites not aligning to the query:
>WP_057508383.1 NCBI__GCF_001431535.1:WP_057508383.1
MSESSKPAHERALSLATLAIHGGQSPDPSTGAVMPPIYATSTYAQSSPGEHQGFEYSRTH
NPTRFAYERCVASLEGGSRGFAFASGMAATSTVMELLDAGSHVVAMDDIYGGTFRLFERV
RRRTAGLDFSFVDLTDLAAFEAAITPATKMVWIETPTNPMLKIVDIAAVAAIAKQHGLII
VVDNTFASPMLQRPLELGADLVLHSATKYLNGHSDMVGGMVVVGDNTGLAEQMAFLQNSI
GAVQGPFDSFLALRGLKTLPLRMKAHCANALALAQWLETQPSVEKVIYPGLTSHPQHELA
TRQMNGYGGIVSIVLKGGFEAAKRFCERTELFTLAESLGGVESLVNHPAVMTHASIPVER
RENLGISEGLVRLSVGVEELGDLMVDLERALQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory