Comparing WP_057508708.1 NCBI__GCF_001431535.1:WP_057508708.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
28% identity, 85% coverage: 47:338/343 of query aligns to 30:372/374 of D2Z028
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 68% coverage: 40:271/343 of query aligns to 94:358/504 of Q10341
Sites not aligning to the query:
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
27% identity, 85% coverage: 49:338/343 of query aligns to 26:344/346 of 5w8oB
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
27% identity, 83% coverage: 49:332/343 of query aligns to 36:358/366 of 6puxA
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
27% identity, 83% coverage: 49:332/343 of query aligns to 35:357/367 of 8f2lA
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
27% identity, 83% coverage: 49:332/343 of query aligns to 35:357/368 of 7rytB
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
23% identity, 79% coverage: 60:329/343 of query aligns to 47:340/350 of 2vavB
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
23% identity, 79% coverage: 60:329/343 of query aligns to 46:338/347 of 2vatA
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
26% identity, 85% coverage: 49:338/343 of query aligns to 36:364/375 of 6iohA
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
26% identity, 85% coverage: 49:338/343 of query aligns to 36:364/366 of 6ioiA
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
23% identity, 72% coverage: 83:329/343 of query aligns to 63:348/358 of P45131
Sites not aligning to the query:
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
24% identity, 54% coverage: 83:267/343 of query aligns to 75:290/387 of Q6FEQ3
Sites not aligning to the query:
>WP_057508708.1 NCBI__GCF_001431535.1:WP_057508708.1
MSFAPSTALRPDSFVPVSVPVEDRVHAARGEFAAVLDMRHAGPRPIRLRYEWVGPADAPV
VVLAGGISANRHVAANAQFVEKGWAEGLVGPGRTLDPQLLRVLAFDFIGADGALDVPIDT
ADQADALAILLDHLGIAQLQAFVGYSYGALVAQQFGVRHRPRVQRLVVVSGAHRAHPYAA
AWRALQRRAVALGQLQCSDENGLALARQFAMLSYRTPEEFSERFDAAPEVINGRVRVAAE
DYLDAAAAQYVARTPVTAWLRLSESIDLHRIEPAQLLLPTVVVAVEGDRLVPLADLVSLV
EGLGPRGSLRVLRSPYGHDAFLKETDRIDAILANAIRIPGETA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory