SitesBLAST
Comparing WP_066329731.1 NCBI__GCF_900100165.1:WP_066329731.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6z1mA Structure of an ancestral glycosidase (family 1) bound to heme (see paper)
42% identity, 97% coverage: 13:462/465 of query aligns to 5:421/423 of 6z1mA
- binding protoporphyrin ix containing fe: P164 (= P178), N165 (≠ Y179), L194 (≠ E212), L195 (= L213), L218 (≠ F236), L220 (≠ F238), N244 (= N263), F247 (= F266), K253 (= K272), Y256 (= Y275), L288 (≠ K304), R318 (≠ K356), Y323 (= Y361)
- binding magnesium ion: H346 (≠ K387), K409 (≠ Q450)
9gcjA The crystal structure of beta-glucosidase from the thermophilic bacterium caldicellulosiruptor saccharolyticus in complex with beta- d-glucose determined at 1.95 a resolution (see paper)
41% identity, 97% coverage: 13:462/465 of query aligns to 10:457/458 of 9gcjA
- binding beta-D-glucopyranose: Q22 (= Q25), H123 (= H132), N167 (= N176), E168 (= E177), N306 (= N311), Y308 (= Y313), E366 (= E370), W413 (= W418), E420 (= E425), W421 (= W426), F429 (= F434)
1w3jA Family 1 b-glucosidase from thermotoga maritima in complex with tetrahydrooxazine (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 7:439/443 of 1w3jA
- active site: R74 (= R88), H118 (= H132), E163 (= E177), V166 (≠ I180), N290 (= N311), Y292 (= Y313), E348 (= E370)
- binding tetrahydrooxazine: Q17 (= Q25), H118 (= H132), E163 (= E177), Y292 (= Y313), E348 (= E370), W395 (= W418), E402 (= E425), W403 (= W426)
1oifA Family 1 b-glucosidase from thermotoga maritima (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 8:440/444 of 1oifA
- active site: R75 (= R88), H119 (= H132), E164 (= E177), V167 (≠ I180), N291 (= N311), Y293 (= Y313), E349 (= E370)
- binding 5-hydroxymethyl-3,4-dihydroxypiperidine: Q18 (= Q25), E164 (= E177), Y293 (= Y313), E349 (= E370), W396 (= W418), E403 (= E425), W404 (= W426), F412 (= F434)
2jalB Beta-glucosidase from thermotoga maritima in complex with cyclophellitol (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 9:441/444 of 2jalB
- active site: R76 (= R88), H120 (= H132), E165 (= E177), V168 (≠ I180), N292 (= N311), Y294 (= Y313), E350 (= E370)
- binding calcium ion: D277 (= D295), E281 (≠ I299)
- binding (1r,2s,3s,4s,5r,6r)-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol: Q19 (= Q25), H120 (= H132), E165 (= E177), E350 (= E370), W397 (= W418), E404 (= E425), W405 (= W426), F413 (= F434)
5ossB Beta-glucosidase from thermotoga maritima in complex with gluco-1h- imidazole (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 8:440/443 of 5ossB
- active site: R75 (= R88), H119 (= H132), E164 (= E177), V167 (≠ I180), N291 (= N311), Y293 (= Y313), E349 (= E370)
- binding (4~{S},5~{S},6~{R},7~{R})-7-(hydroxymethyl)-4,5,6,7-tetrahydro-1~{H}-benzimidazole-4,5,6-triol: Q18 (= Q25), H119 (= H132), E164 (= E177), Y293 (= Y313), E349 (= E370), W396 (= W418), E403 (= E425), W404 (= W426), F412 (= F434)
5n6tA Thermotoga maritima family 1 glycoside hydrolase complexed with a cyclophellitol analogue transition state mimic (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 8:440/443 of 5n6tA
- active site: R75 (= R88), H119 (= H132), E164 (= E177), V167 (≠ I180), N291 (= N311), Y293 (= Y313), E349 (= E370)
- binding [(1~{R},2~{R},3~{R},4~{S},5~{R},6~{S})-3,4,5-tris(oxidanyl)-7-oxabicyclo[4.1.0]heptan-2-yl]methanediazonium: Q18 (= Q25), H119 (= H132), N163 (= N176), E164 (= E177), Y293 (= Y313), E349 (= E370), W396 (= W418), E403 (= E425), W404 (= W426), F412 (= F434)
5n6sA Thermotoga maritima family 1 glycoside hydrolase complexed with carba- cyclophellitol transition state mimic (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 8:440/443 of 5n6sA
- active site: R75 (= R88), H119 (= H132), E164 (= E177), V167 (≠ I180), N291 (= N311), Y293 (= Y313), E349 (= E370)
- binding azanylidene-[4-[[(1~{S},2~{R},3~{R},4~{R},5~{S},6~{S},7~{S})-2-(hydroxymethyl)-3,4,5-tris(oxidanyl)-7-bicyclo[4.1.0]heptanyl]carbonylamino]butylimino]azanium: Q18 (= Q25), H119 (= H132), W120 (≠ F133), N163 (= N176), E164 (= E177), W166 (≠ Y179), V167 (≠ I180), E349 (= E370), W396 (= W418), E403 (= E425), W404 (= W426), F412 (= F434)
2wc4A Structure of family 1 beta-glucosidase from thermotoga maritima in complex with 3-imino-2-thia-(+)-castanospermine (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 8:440/443 of 2wc4A
- active site: R75 (= R88), H119 (= H132), E164 (= E177), V167 (≠ I180), N291 (= N311), Y293 (= Y313), E349 (= E370)
- binding (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol: Q18 (= Q25), H119 (= H132), N163 (= N176), E164 (= E177), Y293 (= Y313), W322 (≠ G343), E349 (= E370), W396 (= W418), E403 (= E425), W404 (= W426), F412 (= F434)
2wbgA Structure of family 1 beta-glucosidase from thermotoga maritima in complex with 3-imino-2-oxa-(+)-castanospermine (see paper)
39% identity, 96% coverage: 15:462/465 of query aligns to 8:440/443 of 2wbgA