SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_068108588.1 NCBI__GCF_001653335.1:WP_068108588.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
34% identity, 94% coverage: 10:212/216 of query aligns to 14:214/214 of 4ymwC

query
sites
4ymwC
L
 
L
Y
 
F
W
 
I
Q
 
S
G
 
G
F
 
L
L
 
I
T
 
M
S
 
T
L
 
L
G
 
K
I
 
L
I
 
T
G
 
F
W
 
L
A
 
A
L
 
V
V
 
T
G
 
I
S
 
G
L
 
V
L
 
L
L
 
M
G
 
G
T
 
L
L
 
F
I
 
I
A
 
A
A
 
L
F
 
M
R
 
K
V
 
M
S
 
S
P
 
S
V
 
I
A
 
K
S
 
P
L
 
I
R
 
K
A
 
L
F
 
V
G
 
A
S
 
S
A
 
S
W
 
Y
V
 
I
T
 
E
V
 
V
V
 
I
R
 
R
N
 
G
C
 
T
P
 
P
L
 
L
T
 
L
I
 
V
V
 
Q
L
 
L
F
 
L
F
 
L
M
 
I
A
 
Y
F
 
N
G
 
G
L
 
L
P
 
M
E
 
Q
V
 
F
G
 
G
I
 
M
N
 
N
V
 
I
S
 
P
F
 
A
Y
 
F
T
 
T
F
 
A
G
 
G
V
 
V
I
 
S
G
 
A
L
 
L
I
 
A
I
 
I
Y
x
N
T
 
S
S
 
S
A
 
A
F
x
Y
V
 
V
C
 
A
E
 
E
A
 
I
I
 
I
R
 
R
S
 
A
G
 
G
I
 
I
N
 
Q
S
 
A
V
 
V
S
 
D
A
 
P
G
 
G
Q
 
Q
A
 
N
E
 
E
A
 
A
A
 
A
R
 
R
A
 
S
I
 
L
G
 
G
L
 
M
P
 
T
F
 
H
T
 
A
K
 
M
T
 
A
L
 
M
T
 
R
Q
 
Y
V
 
V
V
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
L
 
I
R
 
K
A
 
N
T
 
I
V
 
L
P
 
P
P
 
A
L
 
L
G
 
G
S
 
N
V
x
E
Q
 
F
I
 
I
A
 
V
M
 
M
F
 
L
K
 
K
N
x
E
S
 
S
A
 
A
V
 
I
V
 
V
G
 
S
A
 
V
F
 
I
G
 
G
V
 
F
G
 
-
G
 
A
D
 
D
L
 
L
W
 
T
S
 
R
V
 
Q
G
 
A
R
 
D
N
 
I
L
 
I
T
 
Q
S
 
S
A
 
V
Q
 
T
G
 
Y
Y
 
R
A
 
Y
F
 
F
I
 
E
P
 
P
V
 
Y
L
 
I
T
 
I
G
 
I
V
 
A
A
 
A
I
 
I
G
 
-
Y
 
Y
L
 
F
I
 
V
I
 
M
T
 
T
L
 
L
T
 
T
A
 
F
G
 
S
A
 
K
L
 
L
L
 
L
A
 
S
V
 
L
L
 
F
E
 
E
R
 
R
K
 
R
V
 
L

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
34% identity, 94% coverage: 10:212/216 of query aligns to 14:214/215 of 4ymtC

query
sites
4ymtC
L
 
L
Y
 
F
W
 
I
Q
 
S
G
 
G
F
 
L
L
 
I
T
 
M
S
 
T
L
 
L
G
 
K
I
 
L
I
 
T
G
 
F
W
 
L
A
 
A
L
 
V
V
 
T
G
 
I
S
 
G
L
 
V
L
 
L
L
 
M
G
 
G
T
 
L
L
 
F
I
 
I
A
 
A
A
 
L
F
 
M
R
 
K
V
 
M
S
 
S
P
 
S
V
 
I
A
 
K
S
 
P
L
 
I
R
 
K
A
 
L
F
 
V
G
 
A
S
 
S
A
 
S
W
 
Y
V
 
I
T
 
E
V
 
V
V
 
I
R
 
R
N
 
G
C
 
T
P
|
P
L
|
L
T
 
L
I
 
V
V
 
Q
L
 
L
F
 
L
F
 
L
M
 
I
A
 
Y
F
 
N
G
 
G
L
 
L
P
 
M
E
 
Q
V
 
F
G
 
G
I
 
M
N
 
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P
F
 
A
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T
 
T
F
 
A
G
 
G
V
 
V
I
 
S
G
 
A
L
 
L
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A
I
 
I
Y
x
N
T
 
S
S
 
S
A
 
A
F
x
Y
V
 
V
C
 
A
E
 
E
A
 
I
I
 
I
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R
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A
G
 
G
I
 
I
N
 
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S
 
A
V
 
V
S
 
D
A
 
P
G
 
G
Q
 
Q
A
 
N
E
 
E
A
 
A
A
 
A
R
 
R
A
 
S
I
 
L
G
 
G
L
 
M
P
 
T
F
 
H
T
 
A
K
 
M
T
 
A
L
 
M
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R
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Y
V
 
V
V
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
L
 
I
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K
A
 
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I
V
 
L
P
 
P
P
 
A
L
 
L
G
 
G
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N
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E
Q
 
F
I
 
I
A
 
V
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|
M
F
 
L
K
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E
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S
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A
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I
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V
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S
A
 
V
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I
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F
G
 
-
G
 
A
D
 
D
L
 
L
W
 
T
S
 
R
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Q
G
 
A
R
 
D
N
 
I
L
 
I
T
 
Q
S
 
S
A
 
V
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T
G
 
Y
Y
 
R
A
 
Y
F
 
F
I
 
E
P
 
P
V
 
Y
L
 
I
T
 
I
G
 
I
V
 
A
A
 
A
I
 
I
G
 
-
Y
 
Y
L
 
F
I
 
V
I
 
M
T
 
T
L
 
L
T
 
T
A
 
F
G
 
S
A
 
K
L
 
L
L
 
L
A
 
S
V
 
L
L
 
F
E
 
E
R
 
R
K
 
R
V
 
L

Query Sequence

>WP_068108588.1 NCBI__GCF_001653335.1:WP_068108588.1
MSPVLDNLDLYWQGFLTSLGIIGWALVGSLLLGTLIAAFRVSPVASLRAFGSAWVTVVRN
CPLTIVLFFMAFGLPEVGINVSFYTFGVIGLIIYTSAFVCEAIRSGINSVSAGQAEAARA
IGLPFTKTLTQVVLPQALRATVPPLGSVQIAMFKNSAVVGAFGVGGDLWSVGRNLTSAQG
YAFIPVLTGVAIGYLIITLTAGALLAVLERKVAIAR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory