Comparing WP_068464010.1 NCBI__GCF_001541235.1:WP_068464010.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate (see paper)
37% identity, 82% coverage: 4:162/195 of query aligns to 1:157/207 of 1h2fA
1h2eA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
37% identity, 82% coverage: 4:162/195 of query aligns to 1:157/207 of 1h2eA
P9WIC7 Glucosyl-3-phosphoglycerate phosphatase; Mannosyl-3-phosphoglycerate phosphatase; EC 3.1.3.85; EC 3.1.3.70 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
36% identity, 77% coverage: 7:157/195 of query aligns to 6:161/223 of P9WIC7
Sites not aligning to the query:
4qihA The structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c complexes with vo3 (see paper)
36% identity, 77% coverage: 7:157/195 of query aligns to 4:159/209 of 4qihA
4pzaB The complex structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c with inorganic phosphate (see paper)
36% identity, 77% coverage: 7:157/195 of query aligns to 5:160/217 of 4pzaB
1k6mA Crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (see paper)
26% identity, 93% coverage: 6:187/195 of query aligns to 214:386/432 of 1k6mA
Sites not aligning to the query:
5htkA Human heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2) (see paper)
27% identity, 93% coverage: 6:187/195 of query aligns to 221:393/425 of 5htkA
Sites not aligning to the query:
O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 2 papers)
27% identity, 93% coverage: 6:187/195 of query aligns to 251:423/505 of O60825
Sites not aligning to the query:
5hr5A Bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2) (see paper)
27% identity, 93% coverage: 6:187/195 of query aligns to 225:397/424 of 5hr5A
Sites not aligning to the query:
1fbtA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase (see paper)
27% identity, 93% coverage: 6:187/195 of query aligns to 2:174/190 of 1fbtA
1tipA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase (see paper)
27% identity, 93% coverage: 6:187/195 of query aligns to 3:175/191 of 1tipA
1c81A Michaelis complex of fructose-2,6-bisphosphatase
27% identity, 93% coverage: 6:187/195 of query aligns to 3:175/191 of 1c81A
1c80A Regulatory complex of fructose-2,6-bisphosphatase
27% identity, 93% coverage: 6:187/195 of query aligns to 3:175/191 of 1c80A
1c7zA Regulatory complex of fructose-2,6-bisphosphatase
27% identity, 93% coverage: 6:187/195 of query aligns to 3:175/191 of 1c7zA
P07953 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Rattus norvegicus (Rat) (see 3 papers)
27% identity, 93% coverage: 6:187/195 of query aligns to 253:425/471 of P07953
Sites not aligning to the query:
P26285 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Bos taurus (Bovine) (see paper)
27% identity, 93% coverage: 6:187/195 of query aligns to 252:424/531 of P26285
Sites not aligning to the query:
P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see paper)
26% identity, 93% coverage: 6:187/195 of query aligns to 253:425/471 of P16118
Sites not aligning to the query:
4ij6A Crystal structure of a novel-type phosphoserine phosphatase mutant (h9a) from hydrogenobacter thermophilus tk-6 in complex with l-phosphoserine (see paper)
28% identity, 77% coverage: 5:155/195 of query aligns to 2:150/207 of 4ij6A
Sites not aligning to the query:
6hvjA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 3 (see paper)
28% identity, 93% coverage: 6:187/195 of query aligns to 231:403/430 of 6hvjA
Sites not aligning to the query:
6ibxA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 5 (see paper)
28% identity, 93% coverage: 6:187/195 of query aligns to 230:402/429 of 6ibxA
Sites not aligning to the query:
>WP_068464010.1 NCBI__GCF_001541235.1:WP_068464010.1
MRAGVTIYFIRHGETDWNAQSRYQGQADVPLNDKGRGQARRNGETLRALAPETGALPFIA
SPLQRARETMEIVRSAMELPAEGYSLDPRLKEINYGAWQGTLAADLPQVDPDGLAARNLD
TFNWRPEGGESYADLTQRAVGWLDSIDRDCVVVAHGGISRVLRGHLYALEPLAVPDLPVP
QDRILILRRDGMEWI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory