SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_078716121.1 NCBI__GCF_900167125.1:WP_078716121.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
43% identity, 94% coverage: 11:218/222 of query aligns to 9:215/215 of 4ymtC

query
sites
4ymtC
V
 
V
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K
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Y
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F
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I
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I
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M
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K
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F
G
 
L
G
 
A
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I
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G
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V
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L
L
 
M
G
 
G
A
 
L
L
 
F
F
 
I
G
 
A
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L
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M
K
 
K
L
 
M
S
 
S
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S
N
 
I
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K
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P
I
 
I
R
 
K
K
 
L
L
 
V
A
 
A
G
 
S
F
 
S
Y
 
Y
V
 
I
E
 
E
T
 
V
I
 
I
R
 
R
G
 
G
T
 
T
P
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P
M
x
L
L
 
L
V
 
V
Q
 
Q
A
 
L
M
 
L
F
 
L
L
 
I
Y
 
Y
F
 
N
G
 
G
V
 
L
P
 
-
M
 
M
A
 
Q
L
 
F
G
 
G
M
 
M
R
 
N
I
 
I
P
 
P
P
 
A
L
 
F
V
 
T
A
 
A
G
 
G
I
 
V
I
 
S
V
 
A
I
 
L
A
 
A
V
 
I
N
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N
S
 
S
G
 
S
A
 
A
Y
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Y
I
 
V
A
 
A
E
 
E
I
 
I
V
 
I
R
 
R
G
 
A
A
 
G
V
 
I
Q
 
Q
S
 
A
I
 
V
N
 
D
P
 
P
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G
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Q
M
 
N
E
 
E
A
 
A
A
 
A
R
 
R
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S
I
 
L
G
 
G
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M
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T
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H
G
 
A
Q
 
M
A
 
A
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M
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R
Y
 
Y
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V
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I
W
 
I
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A
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I
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I
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L
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A
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L
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G
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N
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E
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F
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I
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V
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x
M
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L
K
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K
D
x
E
T
 
S
S
 
A
L
 
I
L
 
V
M
 
S
V
 
V
I
 
I
G
 
G
V
 
F
G
 
A
E
 
D
L
 
L
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T
R
 
R
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Q
G
 
A
Q
 
D
E
 
I
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I
V
 
Q
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S
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V
N
 
T
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Y
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R
A
 
Y
F
 
F
E
 
E
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L
 
I
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I
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A
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A
M
 
I
Y
 
Y
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A
 
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M
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L
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F
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E
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R
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R
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L
Q
 
R

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
43% identity, 93% coverage: 11:217/222 of query aligns to 9:214/214 of 4ymwC

query
sites
4ymwC
V
 
V
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K
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Y
L
 
T
P
 
P
M
 
L
L
 
F
T
 
I
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S
G
 
G
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L
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I
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M
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L
Y
 
K
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L
T
 
T
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F
G
 
L
G
 
A
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V
A
 
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I
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G
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V
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L
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M
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G
A
 
L
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F
 
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A
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L
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M
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I
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K
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A
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A
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Y
I
 
V
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A
E
 
E
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A
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A
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E
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I
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Y
 
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M
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S
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L
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F
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E
R
 
R
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R
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L

Query Sequence

>WP_078716121.1 NCBI__GCF_900167125.1:WP_078716121.1
MAFQFEPRVVVDTLPMLTRGLELTIYITIGGLAFGFLLGALFGLMKLSRNILIRKLAGFY
VETIRGTPMLVQAMFLYFGVPMALGMRIPPLVAGIIVIAVNSGAYIAEIVRGAVQSINPG
QMEAARSIGLRRGQAMLYVVWPQAFKRMIPPLGNQFIISLKDTSLLMVIGVGELLRTGQE
IVAVNFRAFEVYLAVAIMYLAMTMSISWALRRLERRLQIQTR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory