SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_082797879.1 NCBI__GCF_001584165.1:WP_082797879.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

8wm8B Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with nitrate (see paper)
32% identity, 42% coverage: 130:249/288 of query aligns to 107:226/265 of 8wm8B

query
sites
8wm8B
D
 
D
P
 
P
L
 
I
I
 
F
E
 
Q
F
 
V
Y
 
L
R
 
R
P
 
T
I
 
V
P
 
P
P
 
P
L
 
L
A
 
A
Y
 
W
L
 
L
P
 
P
L
 
I
I
 
S
V
 
L
I
 
A
W
 
A
F
 
F
G
 
Q
I
 
Q
G
 
A
E
 
N
L
 
P
S
 
S
K
 
A
V
 
I
L
 
F
L
 
V
I
 
I
Y
 
F
L
 
I
A
 
T
I
 
S
F
 
I
A
 
W
P
 
P
L
 
I
A
 
L
I
 
L
A
 
N
T
 
T
L
 
T
H
 
V
G
 
G
V
 
V
R
 
Q
R
 
Q
V
 
I
D
 
P
Q
 
Q
N
 
D
R
 
Y
L
 
I
R
 
N
A
 
V
A
 
A
Q
 
K
T
 
V
L
 
L
G
 
R
A
 
L
S
 
K
R
 
G
W
 
V
Q
 
K
L
 
Y
I
 
F
R
 
F
F
 
K
V
 
I
I
 
V
L
 
F
P
 
P
S
 
A
A
 
T
V
 
V
P
 
P
D
 
Y
I
 
I
L
 
F
T
 
T
G
 
G
V
 
L
R
 
R
I
 
I
G
 
G
L
 
I
G
 
G
V
 
L
G
 
S
W
 
W
S
x
L
T
 
A
L
 
I
V
 
V
A
|
A
A
 
A
E
 
E
L
 
M
I
 
L
A
 
V
A
 
G
T
 
G
R
 
V
G
 
G
L
 
I
G
 
G
F
 
S
M
 
F
I
 
I
Q
 
W
S
 
D
A
 
A
A
 
Y
Q
 
N

A0A0H2ZQB9 Ergothioneine transporter EgtUBC from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
33% identity, 50% coverage: 136:279/288 of query aligns to 61:203/506 of A0A0H2ZQB9

query
sites
A0A0H2ZQB9
Y
 
F
R
 
Q
P
 
T
I
 
I
P
 
P
P
 
S
L
 
L
A
 
A
Y
 
L
L
 
L
P
 
G
L
 
L
I
 
F
V
 
I
I
 
P
W
 
L
F
 
M
G
 
G
I
 
I
G
 
G
E
 
T
L
 
L
S
 
P
K
 
A
V
 
L
-
 
T
-
 
A
L
 
L
L
 
V
I
 
I
Y
 
Y
L
 
-
A
 
A
I
 
I
F
 
F
A
 
-
P
 
P
L
 
I
A
 
L
I
 
Q
A
 
N
T
 
T
L
 
I
H
 
T
G
 
G
V
 
L
R
 
K
R
 
G
V
 
I
D
 
D
Q
 
P
N
 
S
R
 
L
L
 
Q
R
 
E
A
 
A
A
 
G
Q
 
I
T
 
A
L
 
F
G
 
G
A
 
M
S
 
T
R
 
R
W
 
W
Q
 
E
L
 
R
I
 
L
R
 
K
F
 
K
V
 
F
I
 
E
L
 
I
P
 
P
S
 
L
A
 
A
V
 
M
P
 
P
D
 
V
I
 
I
L
 
M
T
 
S
G
 
G
V
 
I
R
 
R
I
 
T
G
 
A
-
 
A
-
 
V
L
 
L
G
 
I
V
 
I
G
 
G
W
 
T
S
 
A
T
 
T
L
 
L
V
 
-
A
 
-
A
 
A
E
 
T
L
 
L
I
 
I
A
 
G
A
 
A
T
 
G
R
 
-
G
 
G
L
 
L
G
 
G
F
 
S
M
 
F
I
 
I
Q
 
L
S
 
L
A
 
G
A
 
I
Q
 
D
F
 
R
L
 
N
V
 
N
T
 
A
D
 
S
V
 
L
V
 
I
I
 
L
M
 
I
G
 
G
I
 
A
L
 
L
V
 
S
I
 
S
A
 
A
L
 
V
I
 
L
A
 
A
S
 
I
A
 
A
F
 
F
E
 
N
Y
 
F
G
 
L
L
 
L
R
 
K
W
 
V
L
 
M
Q
 
E
R
 
K

Sites not aligning to the query:

B5Z7I3 Ergothioneine transport permease/ergothioneine binding protein EgtU from Helicobacter pylori (strain G27) (see paper)
28% identity, 40% coverage: 106:221/288 of query aligns to 69:184/553 of B5Z7I3

query
sites
B5Z7I3
L
 
F
L
 
L
A
 
V
I
 
L
A
 
V
T
 
F
A
 
G
I
 
V
P
 
L
I
 
I
G
 
G
I
 
V
L
 
F
I
 
A
G
 
F
L
 
Y
S
 
N
N
 
S
R
 
K
A
 
A
R
 
R
A
 
A
V
 
F
F
 
L
D
 
L
P
 
P
L
 
V
I
 
V
E
 
N
F
 
F
Y
 
L
R
 
Y
P
 
T
I
 
I
P
 
P
P
 
S
L
 
L
A
 
A
Y
 
L
L
 
F
P
 
A
L
 
L
I
 
F
V
 
I
I
 
P
W
 
V
F
 
I
G
 
G
I
 
V
G
 
G
E
 
L
L
 
K
S
 
N
K
 
A
V
 
L
L
 
L
L
 
V
I
 
L
Y
 
V
L
 
L
A
 
Y
I
 
G
F
 
L
A
 
L
P
 
P
L
 
I
A
 
V
I
 
Y
A
 
S
T
 
T
L
 
Y
H
 
N
G
 
A
V
 
L
R
 
K
R
 
E
V
 
V
D
 
R
Q
 
E
N
 
E
R
 
V
L
 
I
R
 
K
A
 
A
A
 
A
Q
 
I
T
 
G
L
 
L
G
 
G
A
 
C
S
 
N
R
 
P
W
 
K
Q
 
E
L
 
L
I
 
F
R
 
F
F
 
R
V
 
V
I
 
H
L
 
F
P
 
L
S
 
L
A
 
A
V
 
I
P
 
P
D
 
Q
I
 
I
L
 
L
T
 
A
G
 
G
V
 
L
R
 
R
I
 
I
G
 
A
L
 
V

Sites not aligning to the query:

Query Sequence

>WP_082797879.1 NCBI__GCF_001584165.1:WP_082797879.1
MSELSVTFAPLELPQDGGEQLSSLQQQRRAVPVRRLSDRSVTLLTVFCLLGLWWLVTASA
LVPPLFLPSPLAVLQKIKSVALDGFVDATLWQHTATSVARVLAALLLAIATAIPIGILIG
LSNRARAVFDPLIEFYRPIPPLAYLPLIVIWFGIGELSKVLLIYLAIFAPLAIATLHGVR
RVDQNRLRAAQTLGASRWQLIRFVILPSAVPDILTGVRIGLGVGWSTLVAAELIAATRGL
GFMIQSAAQFLVTDVVIMGILVIALIASAFEYGLRWLQRKYVPWEGRT

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory