SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_083763520.1 NCBI__GCF_000009985.1:WP_083763520.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 2 papers)
29% identity, 68% coverage: 46:261/316 of query aligns to 28:236/296 of P68183

query
sites
P68183

L

M

V

F

P

P

F

L

L

L

I

M

V

V

L

V

K

A

I

I

S

S

L

L

S

R

E

Q

P

G

Q

N

M

F

G

A

I

T

P

G

P

S

Y

L

M

I

P

P

-

E

L

Q

I

I

D

S

W

W

A

D

E

H

G

-

A

-

F

W

K

K

G

L

T

A

L

L

A

-

G

G

Y

F

N

S

T

V

L

E

L

Q

G

A

D

D

N

G

L

R

-

I

-

T

-

P

-

P

-

P

-

F

-

P

Y

V

L

L

L

L

A

W

Y

L

L

W

G

N

S

S

L

V

K

K

L

V

A

A

G

G

I

I

S

S

T

A

L

I

G

G

C

I

L

V

L

A

L

L

G

S

Y

T

P

T

A

C

A

A

Y

Y

A

A

I

F

A

A

R

R

-

M

-

R

-

F

-

P

A

G

P

K

Q

A

S

T

R

L

R

L

Q

K

A

G

L

M

L

L

M

I

L

F

V

Q

A

M

L

F

P

P

F

A

W

V

T

L

S

S

F

-

L

L

I

V

R

A

V

L

Y

Y

A

A

W

L

I

F

G

D

I

R

L

L

K

-

N

G

E

E

G

Y

L

I

L

P

N

F

M

I

A

G

L

L

Q

N

A

T

L

H

G

G

L

-

I

-

S

-

E

-

P

-

L

-

Q

-

I

-

L

-

E

-

T

-

S

-

T

-

A

-

V

-

V

-

I

-

G

G

M

V

V

I

Y

F

S

A

Y

Y

L

L

P

G

F

G

M

I

I

A

L

L

P

H

L

V

Y

W

A

T

T

I

-

K

-

G

-

Y

L

F

E

E

K

T

M

I

D

D

L

S

S

S

L

L

L

E

E
|
E

A

A

A
|
A

A

A

D

L

L

D

G
|
G

C

A

R

T

P

P

F

W

K

Q

A

A

F

F

L

R

A

L

V

V

T

L

L

L

P
|
P

L

L

S

S

M

V

P

P

G

I

V

L

I

A

A

V

G

V

C

F

M

I

L

L

V

S

F

F

I

I

P

A

A

A

V

I

G

T

E

E

F

V

V

P

I

V

P

A

D

S

L

L

L

L

E190 (= E215) mutation E->A,C,K,L: Reduction of transport rate.
A192 (= A217) mutation A->D,S,L: Loss of transport and MalK dissociation from the membrane.
G196 (= G221) mutation to A: No effect.; mutation to P: Loss of transport and MalK dissociation from the membrane.
P209 (= P234) mutation to A: No effect.

Query Sequence

>WP_083763520.1 NCBI__GCF_000009985.1:WP_083763520.1
MGGPGVPGLAPGRFPGADQMKTLLEGRGGRFLVGLAPYAWLLLFFLVPFLIVLKISLSEP
QMGIPPYMPLIDWAEGAFKGTLAGYNTLLGDNLYLLAYLGSLKLAGISTLGCLLLGYPAA
YAIARAPQSRRQALLMLVALPFWTSFLIRVYAWIGILKNEGLLNMALQALGLISEPLQIL
ETSTAVVIGMVYSYLPFMILPLYATLEKMDLSLLEAAADLGCRPFKAFLAVTLPLSMPGV
IAGCMLVFIPAVGEFVIPDLLGGPDTLVIGKVLWAEFFDNRDWPTASAVAVAMLVLLVVP
IMVFQHFEAKRQERGE

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory