SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_084934011.1 NCBI__GCF_002095475.1:WP_084934011.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
35% identity, 94% coverage: 10:210/214 of query aligns to 13:213/214 of 4ymwC

query
sites
4ymwC
P
 
P
I
 
L
L
 
F
L
 
I
K
 
S
G
 
G
L
 
L
G
 
I
I
 
M
T
 
T
L
 
L
L
 
K
L
 
L
S
 
T
I
 
F
A
 
L
A
 
A
I
 
V
I
 
T
G
 
I
S
 
G
T
 
V
L
 
L
L
 
M
G
 
G
L
 
L
L
 
F
A
 
I
A
 
A
V
 
L
L
 
M
R
 
K
T
 
M
S
 
S
R
 
S
L
 
I
P
 
K
V
 
P
A
 
I
K
 
K
Q
 
L
I
 
V
A
 
A
V
 
S
I
 
S
Y
 
Y
T
 
I
E
 
E
L
 
V
F
 
I
R
 
R
G
 
G
T
 
T
P
 
P
V
 
L
L
 
L
I
 
V
T
 
Q
L
 
L
M
 
L
F
 
L
I
 
I
Y
 
Y
F
 
N
G
 
G
V
 
L
A
 
M
Y
 
Q
F
 
F
G
 
G
Y
 
M
E
 
N
I
 
I
N
 
P
L
 
A
F
 
F
A
 
T
A
 
A
G
 
G
I
 
V
L
 
S
G
 
A
L
 
L
S
 
A
I
 
I
Y
x
N
Q
 
S
G
 
S
A
 
A
Y
|
Y
I
 
V
A
 
A
E
 
E
V
 
I
F
 
I
R
 
R
A
 
A
G
 
G
I
 
I
E
 
Q
A
 
A
V
 
V
P
 
D
K
 
P
G
 
G
Q
 
Q
W
 
N
E
 
E
V
 
A
S
 
A
W
 
R
I
 
S
L
 
L
G
 
G
L
 
M
S
 
T
K
 
H
R
 
A
Q
 
M
T
 
A
F
 
M
M
 
R
S
 
Y
V
 
V
V
 
I
L
 
I
P
 
P
Q
 
Q
T
 
A
R
 
I
G
 
K
I
 
N
V
 
I
L
 
L
P
 
P
P
 
A
L
 
L
A
 
G
G
 
N
Q
x
E
Y
 
F
L
 
I
S
 
V
L
 
M
I
 
L
K
 
K
D
x
E
T
 
S
S
 
A
I
 
I
V
 
V
S
 
S
M
 
V
I
 
I
G
 
G
M
 
F
S
 
A
E
 
D
L
 
L
M
 
T
H
 
R
Q
 
Q
G
 
A
-
 
D
-
 
I
-
 
I
Q
 
Q
A
 
S
I
 
V
V
 
T
D
 
Y
R
 
R
I
 
Y
G
 
F
Q
 
E
P
 
P
V
 
-
V
 
-
I
 
-
Y
 
Y
G
 
I
L
 
I
V
 
I
A
 
A
L
 
A
L
 
I
Y
 
Y
F
 
F
A
 
V
I
 
M
C
 
T
F
 
L
P
 
T
L
 
F
S
 
S
R
 
K
W
 
L
V
 
L
Q
 
S
H
 
L
H
 
F
Q
 
E
T
 
R
R
 
R

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
35% identity, 94% coverage: 10:210/214 of query aligns to 13:213/215 of 4ymtC

query
sites
4ymtC
P
 
P
I
 
L
L
 
F
L
 
I
K
 
S
G
 
G
L
 
L
G
 
I
I
 
M
T
 
T
L
 
L
L
 
K
L
 
L
S
 
T
I
 
F
A
 
L
A
 
A
I
 
V
I
 
T
G
 
I
S
 
G
T
 
V
L
 
L
L
 
M
G
 
G
L
 
L
L
 
F
A
 
I
A
 
A
V
 
L
L
 
M
R
 
K
T
 
M
S
 
S
R
 
S
L
 
I
P
 
K
V
 
P
A
 
I
K
 
K
Q
 
L
I
 
V
A
 
A
V
 
S
I
 
S
Y
 
Y
T
 
I
E
 
E
L
 
V
F
 
I
R
 
R
G
 
G
T
 
T
P
|
P
V
x
L
L
 
L
I
 
V
T
 
Q
L
 
L
M
 
L
F
 
L
I
 
I
Y
 
Y
F
 
N
G
 
G
V
 
L
A
 
M
Y
 
Q
F
 
F
G
 
G
Y
 
M
E
 
N
I
 
I
N
 
P
L
 
A
F
 
F
A
 
T
A
 
A
G
 
G
I
 
V
L
 
S
G
 
A
L
 
L
S
 
A
I
 
I
Y
x
N
Q
 
S
G
 
S
A
 
A
Y
|
Y
I
 
V
A
 
A
E
 
E
V
 
I
F
 
I
R
 
R
A
 
A
G
 
G
I
 
I
E
 
Q
A
 
A
V
 
V
P
 
D
K
 
P
G
 
G
Q
 
Q
W
 
N
E
 
E
V
 
A
S
 
A
W
 
R
I
 
S
L
 
L
G
 
G
L
 
M
S
 
T
K
 
H
R
 
A
Q
 
M
T
 
A
F
 
M
M
 
R
S
 
Y
V
 
V
V
 
I
L
 
I
P
 
P
Q
 
Q
T
 
A
R
 
I
G
 
K
I
 
N
V
 
I
L
 
L
P
 
P
P
 
A
L
 
L
A
 
G
G
 
N
Q
x
E
Y
 
F
L
 
I
S
 
V
L
x
M
I
 
L
K
|
K
D
x
E
T
 
S
S
 
A
I
 
I
V
 
V
S
 
S
M
 
V
I
 
I
G
 
G
M
 
F
S
 
A
E
 
D
L
 
L
M
 
T
H
 
R
Q
 
Q
G
 
A
-
 
D
-
 
I
-
 
I
Q
 
Q
A
 
S
I
 
V
V
 
T
D
 
Y
R
 
R
I
 
Y
G
 
F
Q
 
E
P
 
P
V
 
-
V
 
-
I
 
-
Y
 
Y
G
 
I
L
 
I
V
 
I
A
 
A
L
 
A
L
 
I
Y
 
Y
F
 
F
A
 
V
I
 
M
C
 
T
F
 
L
P
 
T
L
 
F
S
 
S
R
 
K
W
 
L
V
 
L
Q
 
S
H
 
L
H
 
F
Q
 
E
T
 
R
R
 
R

Query Sequence

>WP_084934011.1 NCBI__GCF_002095475.1:WP_084934011.1
MSELIISSFPILLKGLGITLLLSIAAIIGSTLLGLLAAVLRTSRLPVAKQIAVIYTELFR
GTPVLITLMFIYFGVAYFGYEINLFAAGILGLSIYQGAYIAEVFRAGIEAVPKGQWEVSW
ILGLSKRQTFMSVVLPQTRGIVLPPLAGQYLSLIKDTSIVSMIGMSELMHQGQAIVDRIG
QPVVIYGLVALLYFAICFPLSRWVQHHQTRSQIS

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory