SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_084935521.1 NCBI__GCF_002095475.1:WP_084935521.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
38% identity, 90% coverage: 13:211/222 of query aligns to 13:211/214 of 4ymwC

query
sites
4ymwC
P
 
P
F
 
L
L
 
F
L
 
I
K
 
S
G
 
G
A
 
L
L
 
I
F
 
M
T
 
T
L
 
L
Q
 
K
L
 
L
S
 
T
I
 
F
G
 
L
G
 
A
M
 
V
F
 
T
F
 
I
G
 
G
L
 
V
V
 
L
L
 
M
G
 
G
F
 
L
V
 
F
L
 
I
A
 
A
L
 
L
M
 
M
R
 
K
L
 
M
S
 
S
H
 
S
F
 
I
W
 
K
P
 
P
I
 
I
N
 
K
W
 
L
L
 
V
A
 
A
R
 
S
I
 
S
Y
 
Y
V
 
I
S
 
E
I
 
V
F
 
I
R
 
R
G
 
G
T
 
T
P
 
P
L
 
L
I
 
L
A
 
V
Q
 
Q
L
 
L
F
 
L
M
 
L
I
 
I
Y
 
Y
Y
 
N
G
 
G
L
 
L
P
 
M
Q
 
Q
F
 
F
G
 
G
I
 
M
E
 
N
L
 
I
D
 
P
P
 
A
I
 
F
P
 
T
S
 
A
A
 
G
M
 
V
I
 
S
G
 
A
L
 
L
S
 
A
L
 
I
N
|
N
T
 
S
A
 
S
A
 
A
Y
|
Y
A
 
V
S
 
A
E
 
E
S
 
I
L
 
I
R
 
R
G
 
A
A
 
G
I
 
I
A
 
Q
A
 
A
I
 
V
E
 
D
R
 
P
G
 
G
Q
 
Q
W
 
N
E
 
E
A
 
A
A
 
A
A
 
R
S
 
S
I
 
L
G
 
G
M
 
M
S
 
T
P
 
H
W
 
A
Q
 
M
T
 
A
L
 
M
R
 
R
R
 
Y
V
 
V
I
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
A
 
I
R
 
K
T
 
N
A
 
I
L
 
L
P
 
P
P
 
A
L
 
L
G
 
G
N
 
N
S
x
E
F
 
F
I
 
I
S
 
V
L
 
M
V
 
L
K
 
K
D
x
E
T
 
S
S
 
A
L
 
I
A
 
V
A
 
S
T
 
V
I
 
I
Q
 
G
V
 
F
P
 
A
E
 
D
L
 
L
F
 
T
R
 
R
Q
 
Q
A
 
A
Q
 
D
L
 
I
I
 
I
T
 
Q
S
 
S
R
 
V
T
 
T
L
 
Y
E
 
R
V
 
Y
F
 
F
T
 
E
M
 
P
Y
 
Y
L
 
I
A
 
I
A
 
I
S
 
A
L
 
A
I
 
I
Y
 
Y
W
 
F
V
 
V
M
 
M
A
 
T
T
 
L
V
 
T
L
 
F
S
 
S
A
 
K
L
 
L
Q
 
L
N
 
S
R
 
L
L
 
F
E
 
E

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
38% identity, 90% coverage: 13:211/222 of query aligns to 13:211/215 of 4ymtC

query
sites
4ymtC
P
 
P
F
 
L
L
 
F
L
 
I
K
 
S
G
 
G
A
 
L
L
 
I
F
 
M
T
 
T
L
 
L
Q
 
K
L
 
L
S
 
T
I
 
F
G
 
L
G
 
A
M
 
V
F
 
T
F
 
I
G
 
G
L
 
V
V
 
L
L
 
M
G
 
G
F
 
L
V
 
F
L
 
I
A
 
A
L
 
L
M
 
M
R
 
K
L
 
M
S
 
S
H
 
S
F
 
I
W
 
K
P
 
P
I
 
I
N
 
K
W
 
L
L
 
V
A
 
A
R
 
S
I
 
S
Y
 
Y
V
 
I
S
 
E
I
 
V
F
 
I
R
 
R
G
 
G
T
 
T
P
|
P
L
|
L
I
 
L
A
 
V
Q
 
Q
L
 
L
F
 
L
M
 
L
I
 
I
Y
 
Y
Y
 
N
G
 
G
L
 
L
P
 
M
Q
 
Q
F
 
F
G
 
G
I
 
M
E
 
N
L
 
I
D
 
P
P
 
A
I
 
F
P
 
T
S
 
A
A
 
G
M
 
V
I
 
S
G
 
A
L
 
L
S
 
A
L
 
I
N
|
N
T
 
S
A
 
S
A
 
A
Y
|
Y
A
 
V
S
 
A
E
 
E
S
 
I
L
 
I
R
 
R
G
 
A
A
 
G
I
 
I
A
 
Q
A
 
A
I
 
V
E
 
D
R
 
P
G
 
G
Q
 
Q
W
 
N
E
 
E
A
 
A
A
 
A
A
 
R
S
 
S
I
 
L
G
 
G
M
 
M
S
 
T
P
 
H
W
 
A
Q
 
M
T
 
A
L
 
M
R
 
R
R
 
Y
V
 
V
I
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
A
 
I
R
 
K
T
 
N
A
 
I
L
 
L
P
 
P
P
 
A
L
 
L
G
 
G
N
 
N
S
x
E
F
 
F
I
 
I
S
 
V
L
x
M
V
 
L
K
|
K
D
x
E
T
 
S
S
 
A
L
 
I
A
 
V
A
 
S
T
 
V
I
 
I
Q
 
G
V
 
F
P
 
A
E
 
D
L
 
L
F
 
T
R
 
R
Q
 
Q
A
 
A
Q
 
D
L
 
I
I
 
I
T
 
Q
S
 
S
R
 
V
T
 
T
L
 
Y
E
 
R
V
 
Y
F
 
F
T
 
E
M
 
P
Y
 
Y
L
 
I
A
 
I
A
 
I
S
 
A
L
 
A
I
 
I
Y
 
Y
W
 
F
V
 
V
M
 
M
A
 
T
T
 
L
V
 
T
L
 
F
S
 
S
A
 
K
L
 
L
Q
 
L
N
 
S
R
 
L
L
 
F
E
 
E

Query Sequence

>WP_084935521.1 NCBI__GCF_002095475.1:WP_084935521.1
MQESLQLVLDSAPFLLKGALFTLQLSIGGMFFGLVLGFVLALMRLSHFWPINWLARIYVS
IFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAYASESLRGAIAAIERGQWE
AAASIGMSPWQTLRRVILPQAARTALPPLGNSFISLVKDTSLAATIQVPELFRQAQLITS
RTLEVFTMYLAASLIYWVMATVLSALQNRLEAHVNRQDREVK

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory