Comparing WP_084936660.1 NCBI__GCF_002095475.1:WP_084936660.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
43% identity, 75% coverage: 70:278/278 of query aligns to 63:277/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
43% identity, 75% coverage: 70:278/278 of query aligns to 63:277/280 of 6j5xA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
40% identity, 77% coverage: 65:277/278 of query aligns to 59:274/277 of 6iymA
O06724 Oxaloacetate tautomerase YisK; Oxaloacetate decarboxylase YisK; EC 5.3.2.2; EC 4.1.1.112 from Bacillus subtilis (strain 168) (see paper)
33% identity, 78% coverage: 60:277/278 of query aligns to 76:300/301 of O06724
Sites not aligning to the query:
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
33% identity, 78% coverage: 60:277/278 of query aligns to 76:300/303 of 8skyB
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
33% identity, 78% coverage: 60:277/278 of query aligns to 77:301/303 of 8sutA
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
34% identity, 77% coverage: 65:277/278 of query aligns to 51:278/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
34% identity, 77% coverage: 65:277/278 of query aligns to 51:278/290 of 8gsrA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
32% identity, 94% coverage: 18:278/278 of query aligns to 12:276/279 of 6v77B
3r6oA Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
31% identity, 86% coverage: 38:277/278 of query aligns to 24:260/265 of 3r6oA
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
38% identity, 78% coverage: 61:278/278 of query aligns to 49:267/269 of 4dbhA
1gttA Crystal structure of hpce (see paper)
33% identity, 72% coverage: 47:247/278 of query aligns to 209:391/421 of 1gttA
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
34% identity, 78% coverage: 61:278/278 of query aligns to 49:248/252 of 3qdfA
P76004 Oxaloacetate tautomerase YcgM; EC 5.3.2.2 from Escherichia coli (strain K12)
36% identity, 62% coverage: 76:248/278 of query aligns to 18:197/219 of P76004
Q6P587 Oxaloacetate tautomerase FAHD1, mitochondrial; Acylpyruvase FAHD1; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; ODx; YisK-like protein; EC 5.3.2.2; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 4 papers)
35% identity, 62% coverage: 76:248/278 of query aligns to 16:194/221 of Q6P587
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
35% identity, 62% coverage: 76:248/278 of query aligns to 14:192/218 of 6fogA
Sites not aligning to the query:
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
33% identity, 72% coverage: 77:277/278 of query aligns to 14:213/216 of 6sbiA
Q8R0F8 Oxaloacetate tautomerase FAHD1, mitochondrial; Acylpyruvase FAHD1; Acylpyruvate hydrolase; ApH; Fumarylacetoacetate hydrolase domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; ODx; EC 5.3.2.2; EC 3.7.1.5; EC 4.1.1.112 from Mus musculus (Mouse) (see paper)
33% identity, 72% coverage: 77:277/278 of query aligns to 17:216/221 of Q8R0F8
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
29% identity, 94% coverage: 17:278/278 of query aligns to 12:261/264 of 6jvwB
6j5yA Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
32% identity, 62% coverage: 76:248/278 of query aligns to 25:208/233 of 6j5yA
>WP_084936660.1 NCBI__GCF_002095475.1:WP_084936660.1
MQLCSFYLIDQERKSYGIVREEGVIDVGSRLGAECPDLKSLLQRGAVSDLEAFSSLPADH
PYSAIRFLPVVENPGKVFCVGMNYADKRKEFAETLDAPTLFVRFADSLAGHEQPLLKPAT
TQEFDYEGELAVIIGKAAYQVKAADALQHVAGYSCFMDATVRDMQFTWFTAGKNWQQTGG
FGPWMTTADEIPDPQQLAIKTWLNEREVQNDTTASMVHPVAKIIEYISAFSPLSPGDVII
TGSPGGVGKKRTPPLFMFPGDVIEVEIEKIGRLRHTVV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory