SitesBLAST
Comparing WP_085126186.1 NCBI__GCF_900177295.1:WP_085126186.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
49% identity, 98% coverage: 6:398/400 of query aligns to 5:396/654 of P36204
- R36 (= R37) binding substrate
- R118 (= R120) binding substrate
- R151 (= R153) binding substrate
1vpeA Crystallographic analysis of phosphoglycerate kinase from the hyperthermophilic bacterium thermotoga maritima (see paper)
49% identity, 98% coverage: 6:396/400 of query aligns to 4:393/398 of 1vpeA
- active site: R35 (= R37), K196 (= K199), G353 (= G356), G376 (= G379)
- binding phosphoaminophosphonic acid-adenylate ester: G194 (= G197), A195 (= A198), K196 (= K199), K200 (= K203), G218 (= G221), A219 (≠ G222), N316 (= N318), P318 (= P320), G320 (= G322), V321 (≠ A323), E323 (= E325), G352 (= G355), G353 (= G356), D354 (= D357), S355 (≠ T358)
P40924 Phosphoglycerate kinase; EC 2.7.2.3 from Bacillus subtilis (strain 168) (see paper)
48% identity, 99% coverage: 5:398/400 of query aligns to 4:393/394 of P40924
- S183 (≠ E185) modified: Phosphoserine
- T299 (= T301) modified: Phosphothreonine
1phpA Structure of the adp complex of the 3-phosphoglycerate kinase from bacillus stearothermophilus at 1.65 angstroms (see paper)
48% identity, 99% coverage: 5:398/400 of query aligns to 4:393/394 of 1phpA
- active site: R36 (= R37), K197 (= K199), G351 (= G356), G374 (= G379)
- binding adenosine-5'-diphosphate: G195 (= G197), K201 (= K203), G219 (= G221), G220 (= G222), L237 (= L239), N316 (= N318), P318 (= P320), G320 (= G322), V321 (≠ A323), E323 (= E325), G350 (= G355), D352 (= D357), S353 (≠ T358)
P18912 Phosphoglycerate kinase; EC 2.7.2.3 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
48% identity, 99% coverage: 5:398/400 of query aligns to 4:393/394 of P18912
4feyA An x-ray structure of a putative phosphogylcerate kinase with bound adp from francisella tularensis subsp. Tularensis schu s4
45% identity, 99% coverage: 4:400/400 of query aligns to 3:390/392 of 4feyA
- active site: R36 (= R37), K193 (= K199), G346 (= G356), G369 (= G379)
- binding adenosine-5'-diphosphate: G191 (= G197), S192 (≠ A198), K197 (= K203), G215 (= G221), G316 (= G322), V317 (≠ A323), E319 (= E325), D347 (= D357)
4ng4B Structure of phosphoglycerate kinase (cbu_1782) from coxiella burnetii (see paper)
45% identity, 99% coverage: 4:400/400 of query aligns to 2:388/389 of 4ng4B
- active site: R35 (= R37), K191 (= K199), G344 (= G356), G367 (= G379)
- binding adenosine-5'-diphosphate: G189 (= G197), K195 (= K203), G213 (= G221), I286 (= I294), N310 (= N318), G311 (= G319), P312 (= P320), V315 (≠ A323), E317 (= E325), G343 (= G355), D345 (= D357), T346 (= T358)
- binding magnesium ion: D288 (= D296), G314 (= G322), F321 (= F329), S322 (≠ D330), T325 (= T333)
2wzcA The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp, 3pg and aluminium tetrafluoride (see paper)
45% identity, 98% coverage: 6:398/400 of query aligns to 6:404/405 of 2wzcA
- active site: R37 (= R37), K204 (= K199), G362 (= G356), G385 (= G379)
- binding adenosine-5'-diphosphate: G202 (= G197), A203 (= A198), K204 (= K199), K208 (= K203), G226 (= G221), G227 (= G222), N325 (= N318), P327 (= P320), G329 (= G322), V330 (≠ A323), E332 (= E325), G361 (= G355), D363 (= D357), T364 (= T358)
- binding tetrafluoroaluminate ion: R37 (= R37), K204 (= K199), K208 (= K203), G361 (= G355), G362 (= G356), G384 (= G378)
2wzbA The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp, 3pg and magnesium trifluoride (see paper)
45% identity, 98% coverage: 6:398/400 of query aligns to 6:404/405 of 2wzbA
- active site: R37 (= R37), K204 (= K199), G362 (= G356), G385 (= G379)
- binding adenosine-5'-diphosphate: G202 (= G197), A203 (= A198), K204 (= K199), K208 (= K203), G226 (= G221), G227 (= G222), N325 (= N318), P327 (= P320), G329 (= G322), V330 (≠ A323), E332 (= E325), G361 (= G355), D363 (= D357), T364 (= T358)
- binding trifluoromagnesate: K204 (= K199), K208 (= K203), G361 (= G355), G384 (= G378), G385 (= G379)
4axxA The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp 3-phosphoglycerate and beryllium trifluoride (see paper)
45% identity, 98% coverage: 6:398/400 of query aligns to 6:406/407 of 4axxA
- active site: R37 (= R37), K206 (= K199), G364 (= G356), G387 (= G379)
- binding adenosine-5'-diphosphate: G204 (= G197), A205 (= A198), K210 (= K203), G228 (= G221), G229 (= G222), N327 (= N318), P329 (= P320), G331 (= G322), V332 (≠ A323), E334 (= E325), G363 (= G355), G364 (= G356), D365 (= D357), T366 (= T358)
- binding beryllium trifluoride ion: K206 (= K199), K210 (= K203), G363 (= G355)
2x15A The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp and 1,3- bisphosphoglycerate
45% identity, 98% coverage: 6:398/400 of query aligns to 6:407/408 of 2x15A
- active site: R37 (= R37), K207 (= K199), G365 (= G356), G388 (= G379)
- binding adenosine-5'-diphosphate: G205 (= G197), A206 (= A198), K207 (= K199), K211 (= K203), G229 (= G221), G230 (= G222), N328 (= N318), P330 (= P320), G332 (= G322), V333 (≠ A323), E335 (= E325), G364 (= G355), G365 (= G356), D366 (= D357), T367 (= T358)
- binding adenosine-5'-triphosphate: G205 (= G197), A206 (= A198), K207 (= K199), K211 (= K203), G229 (= G221), G230 (= G222), N328 (= N318), G332 (= G322), V333 (≠ A323), E335 (= E325), G364 (= G355), G365 (= G356), D366 (= D357), T367 (= T358), G387 (= G378), G388 (= G379)
- binding 1,3-bisphosphoglyceric acid: D22 (= D22), N24 (= N24), R37 (= R37), H61 (= H60), R64 (= R63), R121 (= R120), R162 (= R153), K207 (= K199), K211 (= K203), G364 (= G355), G387 (= G378), G388 (= G379)
2wzdA The catalytically active fully closed conformation of human phosphoglycerate kinase k219a mutant in complex with adp, 3pg and aluminium trifluoride (see paper)
45% identity, 98% coverage: 6:398/400 of query aligns to 6:404/405 of 2wzdA