SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_085217773.1 NCBI__GCF_900177405.1:WP_085217773.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

1qwrA Crystal structure analysis of the mannose 6-phosphate isomerase from bacillus subtilis
34% identity, 47% coverage: 55:185/277 of query aligns to 81:217/315 of 1qwrA

query
sites
1qwrA
L
 
L
L
 
L
V
 
T
K
 
K
H
 
L
L
 
L
F
 
D
A
 
V
A
 
K
E
 
E
K
 
D
L
 
T
S
 
S
V
 
I
Q
 
K
V
 
V
H
|
H
P
 
P
G
 
D
D
 
D
A
 
Y
Y
 
Y
A
 
A
Q
 
G
A
 
E
L
 
N
G
 
E
H
 
E
A
 
G
G
 
E
-
 
L
G
 
G
K
 
K
D
 
T
E
|
E
A
 
C
W
 
W
I
 
Y
I
 
I
T
 
I
N
 
D
A
 
C
E
 
K
P
 
E
G
 
N
A
 
A
A
 
E
I
 
I
G
 
I
L
 
Y
G
 
G
-
 
H
-
 
T
L
 
A
R
 
R
R
 
S
P
 
K
L
 
T
D
 
E
A
 
L
E
 
V
A
 
T
L
 
M
R
 
I
N
 
N
A
 
S
A
 
G
L
 
-
D
 
-
G
 
-
S
 
-
I
 
-
E
 
-
Q
 
-
E
 
-
I
 
-
D
 
D
W
 
W
Q
 
E
P
 
G
V
 
L
Q
 
L
R
 
R
-
 
R
-
 
I
-
 
K
-
 
I
-
 
K
-
 
P
G
 
G
D
 
D
V
 
F
I
 
Y
C
 
Y
V
 
V
P
 
P
A
 
S
G
 
G
T
 
T
I
 
L
H
|
H
A
 
A
I
 
L
G
 
C
P
 
K
G
 
G
V
 
A
S
 
L
L
 
V
I
 
L
E
 
E
M
 
T
Q
 
Q
Q
 
Q
P
 
N
N
 
S
D
 
D
I
 
A
T
 
T
Y
 
Y
R
 
R
L
 
V
Y
 
Y
D
 
D
Y
 
Y
-
 
D
-
 
R
-
 
L
-
 
D
-
 
S
-
 
N
G
 
G
R
 
S
G
 
P
R
 
R
D
 
E
L
 
L
H
 
H
L
 
F
E
 
A
D
 
K
A
 
A
L
 
V
A
 
N
V
 
A
A
 
A

P39841 Putative mannose-6-phosphate isomerase YvyI; Phosphohexomutase; Phosphomannose isomerase; PMI; EC 5.3.1.8 from Bacillus subtilis (strain 168)
34% identity, 47% coverage: 55:185/277 of query aligns to 82:218/316 of P39841

query
sites
P39841
L
 
L
L
 
L
V
 
T
K
 
K
H
 
L
L
 
L
F
 
D
A
 
V
A
 
K
E
 
E
K
 
D
L
 
T
S
 
S
V
 
I
Q
 
K
V
 
V
H
|
H
P
 
P
G
 
D
D
 
D
A
 
Y
Y
 
Y
A
 
A
Q
 
G
A
 
E
L
 
N
G
 
E
H
 
E
A
 
G
G
 
E
-
 
L
G
 
G
K
 
K
D
 
T
E
|
E
A
 
C
W
 
W
I
 
Y
I
 
I
T
 
I
N
 
D
A
 
C
E
 
K
P
 
E
G
 
N
A
 
A
A
 
E
I
 
I
G
 
I
L
 
Y
G
 
G
-
 
H
-
 
T
L
 
A
R
 
R
R
 
S
P
 
K
L
 
T
D
 
E
A
 
L
E
 
V
A
 
T
L
 
M
R
 
I
N
 
N
A
 
S
A
 
G
L
 
-
D
 
-
G
 
-
S
 
-
I
 
-
E
 
-
Q
 
-
E
 
-
I
 
-
D
 
D
W
 
W
Q
 
E
P
 
G
V
 
L
Q
 
L
R
 
R
-
 
R
-
 
I
-
 
K
-
 
I
-
 
K
-
 
P
G
 
G
D
 
D
V
 
F
I
 
Y
C
 
Y
V
 
V
P
 
P
A
 
S
G
 
G
T
 
T
I
 
L
H
|
H
A
 
A
I
 
L
G
 
C
P
 
K
G
 
G
V
 
A
S
 
L
L
 
V
I
 
L
E
 
E
M
 
T
Q
 
Q
Q
 
Q
P
 
N
N
 
S
D
 
D
I
 
A
T
 
T
Y
 
Y
R
 
R
L
 
V
Y
 
Y
D
 
D
Y
 
Y
-
 
D
-
 
R
-
 
L
-
 
D
-
 
S
-
 
N
G
 
G
R
 
S
G
 
P
R
 
R
D
 
E
L
 
L
H
 
H
L
 
F
E
 
A
D
 
K
A
 
A
L
 
V
A
 
N
V
 
A
A
 
A

Query Sequence

>WP_085217773.1 NCBI__GCF_900177405.1:WP_085217773.1
MATARKALSATARQLQPRATERVWGCSTLPAPFAALAASDRPTGEIWFDPPPGALLVKHL
FAAEKLSVQVHPGDAYAQALGHAGGKDEAWIITNAEPGAAIGLGLRRPLDAEALRNAALD
GSIEQEIDWQPVQRGDVICVPAGTIHAIGPGVSLIEMQQPNDITYRLYDYGRGRDLHLED
ALAVARREPFRNACPPRPSGPGRTVFSGLAFTLERLEGAQTLHVGGHSRPPLTLAVVAGA
GRLDGVAIGAGEVWSIDAPAHLRLDSGADAILAYYPA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory