Comparing WP_085635729.1 NCBI__GCF_002115805.1:WP_085635729.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
31% identity, 99% coverage: 3:387/388 of query aligns to 1:379/381 of 8uw6B
Sites not aligning to the query:
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
26% identity, 94% coverage: 10:372/388 of query aligns to 13:367/383 of 7uoiA
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
26% identity, 85% coverage: 10:339/388 of query aligns to 24:384/426 of 3pfoA
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
26% identity, 80% coverage: 74:384/388 of query aligns to 72:363/366 of Q8P8J5
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
26% identity, 80% coverage: 74:384/388 of query aligns to 73:358/360 of 2f7vA
7lgpB Dape enzyme from shigella flexneri
26% identity, 83% coverage: 66:388/388 of query aligns to 60:377/377 of 7lgpB
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
27% identity, 86% coverage: 57:388/388 of query aligns to 51:376/377 of 7t1qA
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
24% identity, 82% coverage: 69:388/388 of query aligns to 62:376/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
24% identity, 82% coverage: 69:386/388 of query aligns to 62:374/375 of 4pqaA
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
25% identity, 82% coverage: 69:386/388 of query aligns to 62:374/377 of P44514
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
25% identity, 82% coverage: 69:386/388 of query aligns to 66:378/380 of 5vo3A
Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human)
35% identity, 34% coverage: 69:200/388 of query aligns to 94:231/475 of Q96KP4
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
35% identity, 29% coverage: 69:179/388 of query aligns to 64:183/258 of 4h2kA
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
22% identity, 82% coverage: 69:388/388 of query aligns to 75:399/407 of P37111
Sites not aligning to the query:
Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 2 papers)
41% identity, 22% coverage: 69:153/388 of query aligns to 94:181/475 of Q9D1A2
Sites not aligning to the query:
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
41% identity, 22% coverage: 69:153/388 of query aligns to 98:185/478 of 2zogA
Sites not aligning to the query:
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
41% identity, 22% coverage: 69:153/388 of query aligns to 98:185/478 of 2zofA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
34% identity, 26% coverage: 52:150/388 of query aligns to 109:211/507 of Q96KN2
Sites not aligning to the query:
3dljA Crystal structure of human carnosine dipeptidase 1
34% identity, 26% coverage: 52:150/388 of query aligns to 78:180/471 of 3dljA
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
22% identity, 83% coverage: 67:388/388 of query aligns to 73:400/408 of Q03154
>WP_085635729.1 NCBI__GCF_002115805.1:WP_085635729.1
MPNRLTPRQILDQLVKFPTVSRDTNLPLIDWVEEYLSEHGVQSHRHVKSDDPTKAALFAH
VGPEVGGGVVLSGHTDVVPTDGQPWSTDPFTVIEKDGKLFGRGTTDMKGFDALAIWALVE
AQHRGVSRPVQVALSYDEEIGCTGAPPLIEAMQGVVPKAETVIVGEPTMLKAVTGHKGGN
TFWVHMHGFEVHSSIMHTGVSAIMYGAKLIEWANRMNAESAAAEPGPIAAQFNPPYTNVH
VGQIKGGTAHNITAKDCEFGLGFRVVPGETLEQWESKLREAAAEIEAEMKAVRPEAWIEI
TPVFSLPPFKPEDGGAAETLVRQLTGDNGTQYVSYGTEASHFQSAGYSVVVCGPGDIAVA
HQPDEYITVAQFNEGQAFMERLLEHLSA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory